Manteia

ID	Phenotype	Definition	Genetic BG
MP:0000026	abnormal inner ear morphology	"malformation or malfunction of any components of the labyrinth, including the semicircular canals, vestibule and cochlea" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:1776]	Show Allelic Composition: Ednrb^s-l/Ednrb^s-l Genetic Background: involves: C3H/HeJ * C57BL/6
MP:0000031	abnormal cochlea morphology	"any anomaly, deformity, malformation, impairment or dysfunction of the cochlea" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, cml:Cathleen M. Lutz , Mouse Genome Informatics Curator, J:21484]	Show Allelic Composition: Ednrb^WS4/Ednrb^WS4 Genetic Background: involves: BALB/c * MSM
MP:0000043	organ of Corti degeneration	"a retrogressive impairment of function or destruction of the highly specialized epithelium in the floor of the ductus cochlearis" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Ednrb^WS4/Ednrb^WS4 Genetic Background: involves: BALB/c * MSM
MP:0000048	abnormal stria vascularis	"anomalous structure of the layer of highly vascularized pigmented granular cells on the outer wall of the cochlear duct" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003]	Show Allelic Composition: Ednrb^WS4/Ednrb^WS4 Genetic Background: involves: BALB/c * MSM Allelic Composition: Ednrb^s-l/Ednrb^s-l Genetic Background: involves: C3H/HeJ * C57BL/6
MP:0000163	abnormal cartilage morphology	"anomalous structure or development of the nonvascular, resilient, flexible connective tissue found primarily in joints, walls of the throax, and tubular structures, but which also comprises most of the skeleton in early fetal life " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Ednrb^s/Ednrb^s-4Pub Genetic Background: involves: 101/Rl * C3H/Rl
MP:0000291	enlarged pericardium	"extended fibroserous membrane covering the heart and beginning of the great vessels" [J:29971]	Show Allelic Composition: Ednrb^s-24Pub/Ednrb⁺,Mycbp2^m274-4Tpo/Mycbp2⁺ Genetic Background: involves: 101/Rl * C3H/Rl * C57BL/6J * SSL/LeJ
MP:0000351	increased cell proliferation	"greater than the normal growth and reproduction of similar cells" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Cdk2^tm2Sgo/Cdk2^tm2Sgo,Cdk4^tm2.1Bbd/Cdk4^tm2.1Bbd,Polr2a^{tm1(cre/ERT2)Bbd}/? Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL
MP:0000373	belly spot	"the appearance of a round area of white fur on the belly" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Tyrp1^b/Tyrp1^b-65H Genetic Background: involves: 101/H * C3H/HeH
MP:0000431	absent palatine shelf	"missing outgrowth of the palatine bone; normally fuses with maxillary shelf to form secondary palate " [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:17489]	Show Allelic Composition: Cdk2^tm2Sgo/Cdk2^tm2Sgo,Cdk4^tm2.1Bbd/Cdk4^tm2.1Bbd,Polr2a^{tm1(cre/ERT2)Bbd}/? Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL
MP:0000432	abnormal head morphology	"anomalous structure or development of the portion of the body containing the brain and organs of sight, hearing, taste, and smell " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Ednrb^s-24Pub/Ednrb⁺,Mycbp2^m274-4Tpo/Mycbp2⁺ Genetic Background: involves: 101/Rl * C3H/Rl * C57BL/6J * SSL/LeJ
MP:0000495	abnormal colon morphology	"malformation of the portion of the large intestine between the cecum and the rectum" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Slc26a4^loop/Slc26a4^loop Genetic Background: C3HeB/FeJ-Slc26a4^loop
MP:0000511	abnormal intestinal mucosa morphology	"structural or developmental anomalies of the mucous lining of the intestine; this consists of epithelium, lamina, propria, and a layer of smooth muscle cells" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Slc26a4^loop/Slc26a4^loop Genetic Background: C3HeB/FeJ-Slc26a4^loop
MP:0000689	abnormal spleen morphology	"atypical structure of the organ that functions to filter blood and to store red corpuscles and platelets" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:27463]	Show Allelic Composition: Ednrb^tm1Nrd/Ednrb^tm1Nrd,Gt(ROSA)26Sor^{tm14(CAG-tdTomato)Hze}/Gt(ROSA)26Sor⁺,H2afv^{Tg(Wnt1-cre)11Rth}/0 Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6 * CBA/J
MP:0000692	small spleen	"decreased spleen size" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Ednrb^tm1Nrd/Ednrb^tm1Nrd,Gt(ROSA)26Sor^{tm14(CAG-tdTomato)Hze}/Gt(ROSA)26Sor⁺,H2afv^{Tg(Wnt1-cre)11Rth}/0 Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6 * CBA/J
MP:0000696	abnormal Peyer s patches morphology	"anomalous structure, development, or cellular make-up of the lymphoid tissue located on the mucosa of the small intestine" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Ednrb^tm1Nrd/Ednrb^tm1Nrd,Gt(ROSA)26Sor^{tm14(CAG-tdTomato)Hze}/Gt(ROSA)26Sor⁺,H2afv^{Tg(Wnt1-cre)11Rth}/0 Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6 * CBA/J
MP:0001044	abnormal enteric nervous system morphology	"malformation or absence of the part of the autonomic nervous system that innervates the esophagus, stomach, small and large bowel" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Ednrb^s-l/Ednrb^s-l Genetic Background: involves: C3H/HeJ * C57BL/6
MP:0001046	abnormal enteric neuron morphology	"malformed or absent neurons that innervate the esophagus, stomach, small and large bowel" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Ednrb^{tm2(rtTA)Tilg}/Ednrb^{tm3(tetO)Tilg} Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv Allelic Composition: Ednrb^tm1(tTA)Tilg/Ednrb^{tm3(tetO)Tilg} Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv
MP:0001048	absent enteric neurons	"missing neurons that innervate the esophagus, stomach, small and large bowel" [Principles of Neural Science:ISBN 0-8385-8034-3, J:49471]	Show Allelic Composition: Ednrb^s-l/Ednrb^s-l Genetic Background: involves: C3H/HeJ * C57BL/6
MP:0001053	abnormal neuromuscular synapse	"malformed or absent membrane to membrane contact of a motor axon and a muscle myofiber resulting in aberrant transmission of nerve impulses" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:60159, J:47439]	Show Allelic Composition: Ednrb^s-15DttMb/Ednrb^s-15DttMb Genetic Background: involves: 101/Rl * C3H/Rl
MP:0001078	abnormal phrenic nerve	"malformed or misprojection of motor and sensory neuron axons to the diaphragm and other tissues" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:60159]	Show Allelic Composition: Ednrb^s-15DttMb/Ednrb^s-15DttMb Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Ednrb^s-15DttMb/Ednrb^s-15DttMb Genetic Background: involves: 101/Rl * C3H/Rl * C57BL/6J
MP:0001265	reduced body size	"smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170]	Show Allelic Composition: Myo5a^d-nBtlr/Myo5a^d-nBtlr Genetic Background: C57BL/6J-Myo5a^d-nBtlr Allelic Composition: Ednrb^s/Ednrb^s-13Pub Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Ednrb^s-17Pub/Ednrb⁺ Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Ednrb^s/Ednrb^s-17Pub Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Ednrb^s-1Acrg/Ednrb⁺ Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Ednrb^s/Ednrb^s-1Acrg Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Ednrb^s-1MLPf/Ednrb⁺ Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Ednrb^s/Ednrb^s-1MLPf Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Ednrb^s-1Pu/Ednrb⁺ Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Ednrb^s/Ednrb^s-1Pu Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Ednrb^s-1XMLP/Ednrb⁺ Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Ednrb^s/Ednrb^s-1XMLP Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Ednrb^s-1XMLPc/Ednrb⁺ Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Ednrb^s/Ednrb^s-1XMLPc Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Ednrb^s-24Pub/Ednrb⁺ Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Ednrb^s/Ednrb^s-24Pub Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Ednrb^s-27Pu/Ednrb⁺ Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Ednrb^s/Ednrb^s-27Pu Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Ednrb^s-29Pub/Ednrb⁺ Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Ednrb^s/Ednrb^s-29Pub Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Ednrb^s-2CHLd/Ednrb⁺ Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Ednrb^s/Ednrb^s-2CHLd Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Ednrb^s/Ednrb^s-2Etopc Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Ednrb^s-2Etopc/Ednrb⁺ Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Ednrb^s/Ednrb^s-2MLPl Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Ednrb^s-2MLPl/Ednrb⁺ Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Ednrb^s-15DttMb/Ednrb⁺ Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Ednrb^s-15DttMb/Ednrb^s Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Ednrb^s-4Chlc/Ednrb⁺ Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Ednrb^s/Ednrb^s-4Chlc Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Ednrb^s-4Pub/Ednrb⁺ Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Ednrb^s/Ednrb^s-4Pub Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Ednrb^s-36Pub/Ednrb⁺ Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Ednrb^s/Ednrb^s-36Pub Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Ednrb^s-31Pub/Ednrb⁺ Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Ednrb^s/Ednrb^s-31Pub Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Ednrb^s-3Etopf/Ednrb⁺ Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Ednrb^s/Ednrb^s-3Etopf Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Ednrb^s/Ednrb^s-48UThc Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Ednrb^s-48UThc/Ednrb⁺ Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Ednrb^s/Ednrb^s-4Blec Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Ednrb^s-4Blec/Ednrb⁺ Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Ednrb^s/Ednrb^s-52Pub Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Ednrb^s-52Pub/Ednrb⁺ Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Ednrb^s/Ednrb^s-9ThW Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Ednrb^s-9ThW/Ednrb⁺ Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Ednrb^s-162H/Ednrb^s-162H Genetic Background: involves: C3H/HeH Allelic Composition: Ednrb^tm1.1Nrd/Ednrb^tm1.1Nrd Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
MP:0001270	distended abdomen	"abdomen appears curved outward or swollen; can be due to skeletal axial defects, enlarged visceral organs or megacolon" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Atp8a2^agil-2J/Atp8a2^agil-2J Genetic Background: AKR/J-Atp8a2^agil-2J/J
MP:0001272	increased metastatic potential		Show Allelic Composition: Ednrb^tm1Ywa/Ednrb⁺,Tg(Mt1-RET)304Ina/0 Genetic Background: involves: 129S7/SvEvBrd * BALB/c * C57BL/6
MP:0001324	abnormal eye pigmentation	"change in the normal black pigmentation of the eye to another color, or lack of color" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Lyst^bg-slt/Lyst^bg-slt,Myo5a^d/Myo5a^d,Oca2^p/Oca2^p,Tyrp1^b/Tyrp1^b Genetic Background: involves: CT/Ch * YZ57/Ch
MP:0001574	abnormal oxygen level	"anomalous concentration of this gaseous element, essential for animal and plant life " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Ednrb^tm1.1Nrd/Ednrb^tm1.1Nrd Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
MP:0001701	incomplete embryo turning	"arrest of the axial rotation of the germ layers of the embryo during the primitive streak/early somite stage (E8.5-E9.5)" [J:62571]	Show Allelic Composition: Ednrb^s-24Pub/Ednrb⁺,Mycbp2^m274-4Tpo/Mycbp2⁺ Genetic Background: involves: 101/Rl * C3H/Rl * C57BL/6J * SSL/LeJ
MP:0001732	postnatal growth retardation	"slow or limited development after birth " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Apoe^tm1Lmh/Apoe⁺ Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
MP:0001807	decreased IgA	"less than normal immunoglobulin class A level" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Ednrb^tm1Nrd/Ednrb^tm1Nrd,Gt(ROSA)26Sor^{tm14(CAG-tdTomato)Hze}/Gt(ROSA)26Sor⁺,H2afv^{Tg(Wnt1-cre)11Rth}/0 Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6 * CBA/J
MP:0001954	respiratory distress	"physical difficulty or inability to breathe" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:54931]	Show Allelic Composition: Ednrb^s-15DttMb/Ednrb^s-15DttMb Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Ednrb^s-24Pub/Ednrb⁺,Mycbp2^m274-4Tpo/Mycbp2⁺ Genetic Background: involves: 101/Rl * C3H/Rl * C57BL/6J * SSL/LeJ
MP:0001963	abnormal hearing	"anomaly in the ability to receive auditory stimuli" [Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8]	Show Allelic Composition: Ednrb^WS4/Ednrb^WS4 Genetic Background: involves: BALB/c * MSM
MP:0001967	deafness	"inability to hear" [J:57651]	Show Allelic Composition: Ednrb^WS4/Ednrb^WS4 Genetic Background: involves: BALB/c * MSM
MP:0002075	abnormal coat color	"irregular or unusual pigmentation pattern of the hair in relation to control animals" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Apoe^tm1Lmh/Apoe⁺ Genetic Background: involves: 129S7/SvEvBrd * C57BL/6 Allelic Composition: Ednrb^s-l/Ednrb^s-l Genetic Background: involves: C3H/HeJ * C57BL/6 Allelic Composition: Ednrb^s-l/Ednrb^s-l Genetic Background: involves: C57BL/6J * SSL/Le Allelic Composition: Ednrb^tm1.1Nrd/Ednrb^tm1.1Nrd Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
MP:0002080	prenatal lethality	"death anytime between fertilization and E18.5" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Ccnd1^tm1Wbg/Ccnd1^tm1Wbg,Ccnd3^tm1Pisc/Ccnd3^tm1Pisc Genetic Background: Not Specified
MP:0002082	postnatal lethality	"premature death anytime after postnatal day 1 to weaning age (3 weeks)" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Ednrb^s-l/Ednrb^s-l Genetic Background: involves: C3H/HeJ * C57BL/6
MP:0002083	premature death	"death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Apoe^tm1Lmh/Apoe⁺ Genetic Background: involves: 129S7/SvEvBrd * C57BL/6 Allelic Composition: Ednrb^WS4/Ednrb^WS4 Genetic Background: involves: BALB/c * MSM Allelic Composition: Ednrb^s-l/Ednrb^s-l Genetic Background: involves: C3H/HeJ * C57BL/6 Allelic Composition: Ednrb^{tm2(rtTA)Tilg}/Ednrb^{tm3(tetO)Tilg} Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv Allelic Composition: Ednrb^tm1Myks/Ednrb^tm1Myks Genetic Background: involves: 129P2/OlaHsd Allelic Composition: Ednrb^tm1Nrd/Ednrb^tm1Nrd,Gt(ROSA)26Sor^tm1(EYFP)Cos/Gt(ROSA)26Sor⁺,H2afv^{Tg(Wnt1-cre)11Rth}/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA/J Allelic Composition: Ednrb^tm1Ywa/Ednrb⁺,Tg(Mt1-RET)304Ina/0 Genetic Background: involves: 129S7/SvEvBrd * BALB/c * C57BL/6
MP:0002152	abnormal brain morphology	"anomalous structure of or abnormal development of the brain, one of the two components of the central nervous system and the center of thought and emotion; controls coordination, bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.)" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, http://cancerweb.ncl.ac.uk]	Show Allelic Composition: Ednrb^s-15DttMb/Ednrb⁺,Mycbp2^tm1.1Adia/Mycbp2⁺ Genetic Background: involves: 101/Rl * C3H/Rl * C57BL/6 * FVB/N
MP:0002191	abnormal artery morphology	"malformation of the blood vessels that carry blood away from the heart" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Ccnd1^tm1Wbg/Ccnd1^tm1Wbg,Ccnd3^tm1Pisc/Ccnd3^tm1Pisc Genetic Background: Not Specified
MP:0002279	abnormal diaphragm morphology	"structural defect in the thin musculomebraneous barrier that separates the abdominal and thoracic cavities; these muscles often used for breathing control" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Ednrb^s-15DttMb/Ednrb^s-15DttMb Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Ednrb^s-15DttMb/Ednrb^s-15DttMb Genetic Background: involves: 101/Rl * C3H/Rl * C57BL/6J
MP:0002318	hypercapnia	"elevated concentration of CO2 in the blood, alveoli or other tissues resulting in the increased pressure of this component of body gases" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Ednrb^tm1Ywa/Ednrb⁺ Genetic Background: involves: 129S/SvEvBrd
MP:0002329	abnormal blood gas	"anomaly in the amount of oxygen and carbon dioxide in the blood" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Ednrb^tm1Ywa/Ednrb⁺ Genetic Background: involves: 129S/SvEvBrd
MP:0002622	abnormal cochlear hair cell morphology	"malformation of the sensory epithelial cells of the cochlea; these cells are in synaptic contact with the auditory nerve" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]	Show Allelic Composition: Ednrb^s-l/Ednrb^s-l Genetic Background: involves: C3H/HeJ * C57BL/6
MP:0002731	megacolon	"extreme dilation of the colon" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:40722]	Show Allelic Composition: Ednrb^WS4/Ednrb^WS4 Genetic Background: involves: BALB/c * MSM Allelic Composition: Ednrb^s-l/Ednrb^s-l Genetic Background: involves: C3H/HeJ * C57BL/6 Allelic Composition: Ednrb^{tm2(rtTA)Tilg}/Ednrb^{tm3(tetO)Tilg} Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv Allelic Composition: Ednrb^tm1(tTA)Tilg/Ednrb^{tm3(tetO)Tilg} Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv Allelic Composition: Ednrb^tm1Myks/Ednrb^tm1Myks Genetic Background: involves: 129P2/OlaHsd Allelic Composition: Ednrb^s-17FrS/Ednrb^s-17FrS Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Ednrb^s-1Chlc/Ednrb^s-1Chlc Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Ednrb^s-27Pub/Ednrb^s-27Pub Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Ednrb^s-3CHLo/Ednrb^s-3CHLo Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Ednrb^s/Ednrb^s Genetic Background: Not Specified Allelic Composition: Ednrb^tm1.1Nrd/Ednrb^tm1.1Nrd Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
MP:0002792	abnormal retinal vascularization	"malformation or disorganization of the blood vessels supplying the retina" [cml:Cathleen M. Lutz , Mouse Genome Informatics Curator]	Show Allelic Composition: Xcr1^tm1Ksho/Xcr1⁺ Genetic Background: involves: C57BL/6 * C57BL/6J
MP:0002842	increased blood pressure	"increased tension of the blood within the systemic arteries" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Pctp^tm1Bor/Pctp^tm1Bor Genetic Background: involves: 129P2/OlaHsd * FVB/NJ
MP:0002884	abnormal branchial arches	"malformation or anomaly in the transient structures of the embryo that develop into regions of the head, neck and ears" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Ednrb^s-24Pub/Ednrb⁺,Mycbp2^m274-4Tpo/Mycbp2⁺ Genetic Background: involves: 101/Rl * C3H/Rl * C57BL/6J * SSL/LeJ
MP:0002926	aganglionic megacolon	"extreme dilation of the colon due to defects in innervation from the ganglia, or absence of the ganglia of the myenteric plexus" [RGD:Rat Genome Database submission, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]	Show Allelic Composition: Apoe^tm1Lmh/Apoe⁺ Genetic Background: involves: 129S7/SvEvBrd * C57BL/6 Allelic Composition: Ednrb^tm1Nrd/Ednrb^tm1Nrd,Gt(ROSA)26Sor^tm1(EYFP)Cos/Gt(ROSA)26Sor⁺,H2afv^{Tg(Wnt1-cre)11Rth}/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA/J
MP:0002938	white spotting	"the appearance of patches of white fur" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Apoe^tm1Lmh/Apoe⁺ Genetic Background: involves: 129S7/SvEvBrd * C57BL/6 Allelic Composition: Ednrb^s/Ednrb^s,Mc1r^e/Mc1r^e Genetic Background: Not Specified Allelic Composition: Ednrb^s/Ednrb^s-13Pub Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Ednrb^s-17FrS/Ednrb^s-17FrS Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Ednrb^s/Ednrb^s-17FrS Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Ednrb^s/Ednrb^s-17Pub Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Ednrb^s/Ednrb^s-1Acrg Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Ednrb^s/Ednrb^s-1Chlc Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Ednrb^s-1Chlc/Ednrb^s-1Chlc Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Ednrb^s/Ednrb^s-1MLPf Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Ednrb^s/Ednrb^s-1Pu Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Ednrb^s/Ednrb^s-1XMLP Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Ednrb^s/Ednrb^s-1XMLPc Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Ednrb^s/Ednrb^s-24Pub Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Ednrb^s/Ednrb^s-27Pu Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Ednrb^s-27Pub/Ednrb^s-27Pub Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Ednrb^s/Ednrb^s-27Pub Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Ednrb^s/Ednrb^s-29Pub Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Ednrb^s/Ednrb^s-2CHLd Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Ednrb^s/Ednrb^s-2Etopc Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Ednrb^s/Ednrb^s-2MLPl Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Ednrb^tm1.1Yko/Ednrb^tm1.1Yko Genetic Background: involves: 129P2/OlaHsd * Bkl:BKW * C57BL/6 * SJL Allelic Composition: Ednrb^tm1Nrd/Ednrb^tm1Nrd,Gt(ROSA)26Sor^tm1(EYFP)Cos/Gt(ROSA)26Sor⁺,H2afv^{Tg(Wnt1-cre)11Rth}/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA/J Allelic Composition: Ednrb^s-12MNURn/Ednrb^s-12MNURn Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Ednrb^s/Ednrb^s-12MNURn Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Ednrb^s-15DttMb/Ednrb^s Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Ednrb^s/Ednrb^s-3CHLo Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Ednrb^s-3CHLo/Ednrb^s-3CHLo Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Ednrb^s/Ednrb^s-4Chlc Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Ednrb^s/Ednrb^s-4Pub Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Ednrb^s/Ednrb^s-36Pub Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Ednrb^s/Ednrb^s-31Pub Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Ednrb^s/Ednrb^s-3Etopf Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Ednrb^s/Ednrb^s-48UThc Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Ednrb^s/Ednrb^s-4Blec Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Ednrb^s/Ednrb^s-52Pub Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Ednrb^s/Ednrb^s-9ThW Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Ednrb^s/Ednrb^s Genetic Background: Not Specified Allelic Composition: Ednrb^s-136H/Ednrb^s-136H Genetic Background: involves: 101/H * C3H/HeH Allelic Composition: Ednrb^s-162H/Ednrb^s-162H Genetic Background: involves: C3H/HeH Allelic Composition: Ednrb^s-160H/Ednrb^s-160H Genetic Background: involves: C3H/HeH Allelic Composition: Ednrb^s-161H/Ednrb^s-161H Genetic Background: involves: C3H/HeH Allelic Composition: Ednrb^tm1.1Nrd/Ednrb^tm1.1Nrd Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
MP:0002939	head spot	"the appearance of a round area of white fur on the head" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Ednrb^s-136H/Ednrb^s-136H Genetic Background: involves: 101/H * C3H/HeH
MP:0002940	variable body spotting	"the appearance of patches of white fur at random on the coat" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Ednrb^WS4/Ednrb^WS4 Genetic Background: involves: BALB/c * MSM Allelic Composition: Ednrb^s/Ednrb^s Genetic Background: Not Specified Allelic Composition: A^y/a,Ednrb^s/Ednrb^s Genetic Background: Not Specified Allelic Composition: Ednrb^s-Btlr/Ednrb^s-Btlr Genetic Background: C57BL/6J-Ednrb^s-Btlr Allelic Composition: Ednrb^s-2Btlr/Ednrb^s-2Btlr Genetic Background: C57BL/6J-Ednrb^s-2Btlr
MP:0003027	abnormal blood pH regulation	"anomaly in the function of the buffer systems of the blood in combination with the respiratory and renal systems that control the relative acidity or alkalinity of the blood, as measured by the concentration of the hydrogen ion" [RGD:Rat Genome Database submission, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Ednrb^tm1.1Nrd/Ednrb^tm1.1Nrd Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
MP:0003032	hypocapnia	"reduced concentration of CO2 in the blood, alveoli or other tissues resulting in the decreased pressure of this component of body gases" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]	Show Allelic Composition: Ednrb^tm1.1Nrd/Ednrb^tm1.1Nrd Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
MP:0003043	hypoalgesia	"decreased sensation to painful stimuli that may follow damage to soft tissue containing nociceptors or injury to a peripheral nerve; it can be primary (at the site of the injury) or secondary (in the surrounding undamaged area)" [ava:Anna V. Anagnostopoulos, Mouse Genome Informatics Curator, MeSH:National Library of Medicine - Medical Subject Headings, 2003]	Show Allelic Composition: Apoe^tm1Lmh/Apoe⁺ Genetic Background: involves: 129S7/SvEvBrd * C57BL/6 Allelic Composition: Ednrb^tm1Ywa/Ednrb⁺ Genetic Background: involves: 129S/SvEvBrd
MP:0003091	abnormal cell migration	"defect in the movement of cells during developmental processes" [smb:Susan M. Bello, Mouse Genome Informatics Curator]	Show Allelic Composition: Ednrb^tm1Myks/Ednrb^tm1Myks Genetic Background: involves: 129P2/OlaHsd
MP:0003136	yellow coat color	"amount and distribution of yellow pigment (phaeomelanin) relative to black or brown pigment (eumelanin) is increased compared to wild-type agouti" [llw2:Linda L. Washburn, Mouse Genome Informatics Curator]	Show Allelic Composition: Ednrb^s/Ednrb^s,Mc1r^e/Mc1r^e Genetic Background: Not Specified
MP:0003154	abnormal soft palate	"abnormality in the musculomembranous fold that partly separates the mouth and pharynx, located behind the hard palate" [smb:Susan M Bello, Mouse Genome Informatics Curator]	Show Allelic Composition: Cdk2^tm2Sgo/Cdk2^tm2Sgo,Cdk4^tm2.1Bbd/Cdk4^tm2.1Bbd,Polr2a^{tm1(cre/ERT2)Bbd}/? Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL
MP:0003229	abnormal vitelline vasculature	"malformation in the vessels of the yolk sac" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:93257]	Show Allelic Composition: Ednrb^s-24Pub/Ednrb⁺,Mycbp2^m274-4Tpo/Mycbp2⁺ Genetic Background: involves: 101/Rl * C3H/Rl * C57BL/6J * SSL/LeJ
MP:0003270	intestinal obstruction	"any impediment, blockage, or reversal of the normal flow of the intestinal contents toward the anus " [MeSH:National Library of Medicine - Medical Subject Headings , 2003, ncbi:Matthew Mailman, NCBI request]	Show Allelic Composition: Apoe^tm1Lmh/Apoe⁺ Genetic Background: involves: 129S7/SvEvBrd * C57BL/6 Allelic Composition: Ednrb^tm1.1Yko/Ednrb^tm1.1Yko Genetic Background: involves: 129P2/OlaHsd * Bkl:BKW * C57BL/6 * SJL
MP:0003304	large intestinal inflammation	"local accumulation of fluid, plasma proteins, and leukocytes in the large intestine" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, ncbi:Matthew Mailman, NCBI request]	Show Allelic Composition: Ednrb^tm1Nrd/Ednrb^tm1Nrd,Gt(ROSA)26Sor^{tm14(CAG-tdTomato)Hze}/Gt(ROSA)26Sor⁺,H2afv^{Tg(Wnt1-cre)11Rth}/0 Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6 * CBA/J
MP:0003308	abnormal cochlear sensory epithelium		Show Allelic Composition: Ednrb^s-l/Ednrb^s-l Genetic Background: involves: C3H/HeJ * C57BL/6
MP:0003394	increased cardiac output	"greater than normal blood volume pumped by each ventricle per minute" [ncbi:Matthew Mailman, NCBI request, smb:Susan M Bello, Mouse Genome Informatics Curator]	Show Allelic Composition: Ednrb^tm1.1Nrd/Ednrb^tm1.1Nrd Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
MP:0003620	decreased urine output	"decreased volume of urine produced and excreted" [ncbi:Matthew Mailman, NCBI request]	Show Allelic Composition: Pctp^tm1Bor/Pctp^tm1Bor Genetic Background: involves: 129P2/OlaHsd * FVB/NJ
MP:0003632	abnormal nervous system morphology		Show Allelic Composition: Map3k12^{Gt(RRN366)Byg}/Map3k12^{Gt(RRN366)Byg},Mycbp2^tm1.1Adia/Mycbp2^tm1.1Adia Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * FVB/N Allelic Composition: Ednrb^s-15DttMb/Ednrb^s-15DttMb Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Ednrb^s-36Pub/Ednrb^s-36Pub Genetic Background: involves: 101/Rl * C3H/Rl
MP:0003868	abnormal feces composition	"increase or decrease in the amount of compunds normally found in the feces (fat, protein etc) or presence of material not normally seen in the feces" [smb:Susan M Bello, Mouse Genome Informatics Curator]	Show Allelic Composition: Slc26a4^loop/Slc26a4^loop Genetic Background: C3HeB/FeJ-Slc26a4^loop
MP:0003957	abnormal nitric oxide homeostasis	"anomaly in the state of equilibrium in the body of nitric oxide, a free radical gas and a potent vasodilator" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Mib1^tm1Kong/Mib1^tm1Kong Genetic Background: involves: 129P2/OlaHsd
MP:0004252	abnormal direction of looping morphogenesis	"deviation from the normal rightward direction of cardiac looping" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]	Show Allelic Composition: Ednrb^s-24Pub/Ednrb⁺,Mycbp2^m274-4Tpo/Mycbp2⁺ Genetic Background: involves: 101/Rl * C3H/Rl * C57BL/6J * SSL/LeJ
MP:0004302	abnormal Dieters cell morphology	"any structural abnormality in the supporting cells of the spiral organ which are attached to the basement membrane and receive the hair cells between their free extremities" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]	Show Allelic Composition: Ednrb^s-l/Ednrb^s-l Genetic Background: involves: C3H/HeJ * C57BL/6
MP:0004362	cochlear hair cell degeneration	"degeneration or loss of the sensory epithelial cells of the cochlea; these cells are in synaptic contact with the auditory nerve" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Ednrb^WS4/Ednrb^WS4 Genetic Background: involves: BALB/c * MSM
MP:0004364	thin stria vascularis	"reduced thickness of the stratified, secretory epithelium which lines the upper part of the cochlear spiral ligament and maintains potassium ion homeostasis in the endolymph" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]	Show Allelic Composition: Ednrb^WS4/Ednrb^WS4 Genetic Background: involves: BALB/c * MSM
MP:0004381	abnormal hair follicle melanocyte morphology	"any structural anomaly of the cells that produce pigment in the hair follicles" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]	Show Allelic Composition: Apoe^tm1Lmh/Apoe⁺ Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
MP:0004486	decreased response of heart to induced stress	"decrease in severity of the physiological response of the heart to induced stress such as cardiac hypertrophy due to mechanical pressure overload from aortic banding" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Ednrb^tm1.1Nrd/Ednrb^tm1.1Nrd Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
MP:0004760	increased mitotic index	"increased number of cells in G2/M phase" [Bertram_Weiss:Bayer_Schering_Pharma_AG]	Show Allelic Composition: Cdk2^tm2Sgo/Cdk2^tm2Sgo,Cdk4^tm2.1Bbd/Cdk4^tm2.1Bbd,Polr2a^{tm1(cre/ERT2)Bbd}/? Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL
MP:0004842	abnormal large intestine crypts of Lieberkuhn morphology	"any structural anomaly in the tubular intestinal glands found in the mucosal membranes of the large intestine" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]	Show Allelic Composition: Slc26a4^loop/Slc26a4^loop Genetic Background: C3HeB/FeJ-Slc26a4^loop
MP:0004875	increased mean arterial blood pressure	"increase in the average arterial pressure during a single cardiac cycle" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Ednrb^tm1Ywa/Ednrb⁺ Genetic Background: involves: 129S/SvEvBrd Allelic Composition: Ednrb^tm1.1Nrd/Ednrb⁺ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
MP:0004953	decreased spleen weight	"reduction in the average weight of the organ that functions to filter blood and to store red corpuscles and platelets" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Ednrb^tm1Nrd/Ednrb^tm1Nrd,Gt(ROSA)26Sor^{tm14(CAG-tdTomato)Hze}/Gt(ROSA)26Sor⁺,H2afv^{Tg(Wnt1-cre)11Rth}/0 Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6 * CBA/J
MP:0005017	decreased B cell number	"fewer than normal B cell numbers" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Ednrb^tm1Nrd/Ednrb^tm1Nrd,Gt(ROSA)26Sor^{tm14(CAG-tdTomato)Hze}/Gt(ROSA)26Sor⁺,H2afv^{Tg(Wnt1-cre)11Rth}/0 Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6 * CBA/J
MP:0005039	hypoxia	"reduced concentration of O2 in the blood, alveoli or other tissues resulting in the decreased pressure of this component of body gases" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Ednrb^tm1Ywa/Ednrb⁺ Genetic Background: involves: 129S/SvEvBrd
MP:0005087	reduced acute inflammation	"less than the expected early reaction of the microcirculation, characterized by movement of fluid and leukocytes from the blood into extravascular tissues; initiated by injury, infection, or local immune response " [Pathology:ISBN 0-397-51047-0, J:74478]	Show Allelic Composition: Apoe^tm1Lmh/Apoe⁺ Genetic Background: involves: 129S7/SvEvBrd * C57BL/6 Allelic Composition: Ednrb^tm1Ywa/Ednrb⁺ Genetic Background: involves: 129S/SvEvBrd
MP:0005100	abnormal choroid pigmentation	"anomalous coloring of the thin, highly vascularized membrane covering most of the posterior of the eye between the retina and the sclera" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Apoe^tm1Lmh/Apoe⁺ Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
MP:0005150	cachexia	"general weight loss and wasting occurring in the course of chronic disease" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Apoe^tm1Lmh/Apoe⁺ Genetic Background: involves: 129S7/SvEvBrd * C57BL/6 Allelic Composition: Ednrb^tm1.1Nrd/Ednrb^tm1.1Nrd Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
MP:0005170	cleft lip	"defect in the upper lip where the maxillary prominence fails to merge with the merged medial nasal prominences" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]	Show Allelic Composition: Cdk2^tm2Sgo/Cdk2^tm2Sgo,Cdk4^tm2.1Bbd/Cdk4^tm2.1Bbd,Polr2a^{tm1(cre/ERT2)Bbd}/? Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL
MP:0005171	lack of coat pigmentation	"fur is devoid of coloration and appears white " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, J:83500]	Show Allelic Composition: Ednrb^{tm2(rtTA)Tilg}/Ednrb^{tm3(tetO)Tilg} Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv Allelic Composition: Ednrb^tm1(tTA)Tilg/Ednrb^{tm3(tetO)Tilg} Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv Allelic Composition: Ednrb^tm1Myks/Ednrb^tm1Myks Genetic Background: involves: 129P2/OlaHsd
MP:0005174	abnormal tail pigmentation	"anomalous color of the tail in relation to control animals" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Ednrb^s/Ednrb^s Genetic Background: Not Specified
MP:0005244	hemopericardium	"bleeding into the pericardial space" [Pathology:ISBN 0-397-51047-0]	Show Allelic Composition: Ednrb^s-24Pub/Ednrb⁺,Mycbp2^m274-4Tpo/Mycbp2⁺ Genetic Background: involves: 101/Rl * C3H/Rl * C57BL/6J * SSL/LeJ
MP:0005312	pericardial effusion	"escape of fluid from blood vessels or lymphatics into the fibrous sac surrounding the heart" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Ccnd1^tm1Wbg/Ccnd1^tm1Wbg,Ccnd3^tm1Pisc/Ccnd3^tm1Pisc Genetic Background: Not Specified
MP:0005508	abnormal skeleton morphology	"malformation of the bony framework of the body in vertebrates" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Ednrb^s-15DttMb/Ednrb⁺,Mycbp2^tm1.1Adia/Mycbp2⁺ Genetic Background: involves: 101/Rl * C3H/Rl * C57BL/6 * FVB/N Allelic Composition: Ednrb^s-36Pub/Ednrb^s-36Pub Genetic Background: involves: 101/Rl * C3H/Rl
MP:0005583	decreased renin activity	"less than the normal ability of this enzyme to cleave angiotensinogen and create angiotensin I" [RGD:Rat Genome Database submission, MeSH:National Library of Medicine - Medical Subject Headings , 2003]	Show Allelic Composition: Pctp^tm1Bor/Pctp^tm1Bor Genetic Background: involves: 129P2/OlaHsd * FVB/NJ
MP:0005591	decreased vasodilation	"less than the expected or normal widening of the lumen of the blood vessels" [RGD:Rat Genome Database submission, Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Mib1^tm1Kong/Mib1^tm1Kong Genetic Background: involves: 129P2/OlaHsd Allelic Composition: Ednrb^tm1.1Yko/Ednrb^tm1.1Yko Genetic Background: involves: 129P2/OlaHsd * Bkl:BKW * C57BL/6 * SJL
MP:0005599	increased cardiac muscle contractility	"greater than the normal ability of the heart muscle to shorten or to develop increased tension " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, RGD:Rat Genome Database submission]	Show Allelic Composition: Ednrb^tm1.1Nrd/Ednrb^tm1.1Nrd Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
MP:0006010	absent cochlear melanocytes	"absence of cochlear melanocytes (neural crest-derived intermediate cells of the stria vascularis) that are required for normal cochlear development." [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator, smb:Susan M Bello, Mouse Genome Informatics Curator]	Show Allelic Composition: Ednrb^WS4/Ednrb^WS4 Genetic Background: involves: BALB/c * MSM
MP:0006143	increased diastolic blood pressure	"abnormal increase in the pressure in the arteries between heart beats when the heart is relaxed" [ncbi:Matthew Mailman, NCBI request, smb:Susan M Bello, Mouse Genome Informatics Curator]	Show Allelic Composition: Pctp^tm1Bor/Pctp^tm1Bor Genetic Background: involves: 129P2/OlaHsd * FVB/NJ
MP:0006144	increased systolic blood pressure	"abnormal increase in the pressure in the arteries as the heart contracts and pumps blood into the arteries" [ncbi:Matthew Mailman, NCBI request, smb:Susan M Bello, Mouse Genome Informatics Curator]	Show Allelic Composition: Pctp^tm1Bor/Pctp^tm1Bor Genetic Background: involves: 129P2/OlaHsd * FVB/NJ
MP:0006274	abnormal urine sodium level	"any change in the level of excretion of sodium in the urine" [smb:Susan M Bello, Mouse Genome Informatics Curator]	Show Allelic Composition: Pctp^tm1Bor/Pctp^tm1Bor Genetic Background: involves: 129P2/OlaHsd * FVB/NJ
MP:0008135	small Peyer s patches	"reduced size of the protruding lymphoid tissue located on the mucosa of the small intestine that is composed of densly packed B cell follicles" [PMID:15841100]	Show Allelic Composition: Ednrb^tm1Nrd/Ednrb^tm1Nrd,Gt(ROSA)26Sor^{tm14(CAG-tdTomato)Hze}/Gt(ROSA)26Sor⁺,H2afv^{Tg(Wnt1-cre)11Rth}/0 Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6 * CBA/J
MP:0008178	decreased germinal center B cell number	"reduced number of rapidly cycling mature B cells which have downregulated IgD expression and exhibit high levels of binding by peanut agglutinin (PNA), and are involved in T-dependent immune responses; germinal center B cells are found typically in the germinal centers of lymph nodes and spleen" [CL:0000844, GO:0002314, ISBN:0781735149]	Show Allelic Composition: Ednrb^tm1Nrd/Ednrb^tm1Nrd,Gt(ROSA)26Sor^{tm14(CAG-tdTomato)Hze}/Gt(ROSA)26Sor⁺,H2afv^{Tg(Wnt1-cre)11Rth}/0 Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6 * CBA/J
MP:0008182	decreased marginal zone B cell number	"reduced number of CD23-negative, CD21-positive B cells of the marginal zone of the spleen expressing a B cell receptor usually reactive to bacterial cell wall components or senescent self components such as oxidized-LDL" [CL:0000845, ISBN:0781735149]	Show Allelic Composition: Ednrb^tm1Nrd/Ednrb^tm1Nrd,Gt(ROSA)26Sor^{tm14(CAG-tdTomato)Hze}/Gt(ROSA)26Sor⁺,H2afv^{Tg(Wnt1-cre)11Rth}/0 Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6 * CBA/J
MP:0008271	abnormal bone ossification	"any anomaly in the formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone or a bony substance" [GO:0001503]	Show Allelic Composition: Cdk2^tm2Sgo/Cdk2^tm2Sgo,Cdk4^tm2.1Bbd/Cdk4^tm2.1Bbd,Polr2a^{tm1(cre/ERT2)Bbd}/? Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL
MP:0008477	decreased spleen red pulp amount	"reduction in the quantity of the parenchymatous tissue network of the spleen that consists of loose plates or cords (sinuses) infiltrated with red blood cells where most of the blood filtration occurs and degenerate erythrocytes are removed from the circulation" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Ednrb^tm1Nrd/Ednrb^tm1Nrd,Gt(ROSA)26Sor^{tm14(CAG-tdTomato)Hze}/Gt(ROSA)26Sor⁺,H2afv^{Tg(Wnt1-cre)11Rth}/0 Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6 * CBA/J
MP:0008479	decreased spleen white pulp amount	"reduction in the quantity of the parenchymatous tissue of the spleen that surrounds splenic blood vessels, consists of compact masses of lymphatic cells and is where foreign material removed from the blood is used to initiate an immune reaction that results in the production of antibodies" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Ednrb^tm1Nrd/Ednrb^tm1Nrd,Gt(ROSA)26Sor^{tm14(CAG-tdTomato)Hze}/Gt(ROSA)26Sor⁺,H2afv^{Tg(Wnt1-cre)11Rth}/0 Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6 * CBA/J
MP:0008489	postnatal slow weight gain	"the weight gain over a span of postnatal developmental time is slower than controls, with or without ever attaining a similar weight to controls as adults" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Ednrb^tm1Nrd/Ednrb^tm1Nrd,Gt(ROSA)26Sor^tm1(EYFP)Cos/Gt(ROSA)26Sor⁺,H2afv^{Tg(Wnt1-cre)11Rth}/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA/J
MP:0008569	lethality at weaning	"premature death at weaning age usually due to the inability to make the transition to solid food" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator", MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]	Show Allelic Composition: Ednrb^s-2Btlr/Ednrb^s-2Btlr Genetic Background: C57BL/6J-Ednrb^s-2Btlr
MP:0008786	abnormal hindgut morphology	"any structural anomaly of the caudal portion of the primitive digestive tube of the embryo" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]	Show Allelic Composition: Ednrb^s-l/Ednrb^s-l Genetic Background: involves: C3H/HeJ * C57BL/6
MP:0008826	abnormal splenic cell ratio	"deviation from the standard ratios of splenocyte subpopulations compared to control samples" [MGI:mberry "Melissa Berry, Genetics Resources Curator"]	Show Allelic Composition: Ednrb^tm1Nrd/Ednrb^tm1Nrd,Gt(ROSA)26Sor^{tm14(CAG-tdTomato)Hze}/Gt(ROSA)26Sor⁺,H2afv^{Tg(Wnt1-cre)11Rth}/0 Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6 * CBA/J
MP:0009379	abnormal foot pigmentation	"anomaly in the coloration of the foot" [MGI:mberry "Melissa Berry, Genetics Resources Curator"]	Show Allelic Composition: Ednrb^s/Ednrb^s Genetic Background: Not Specified
MP:0009642	abnormal blood homeostasis	"anomaly in the processes involved in the maintenance of an internal equilibrium of various functions or chemical or protein composition of the blood" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Mib1^tm1Kong/Mib1^tm1Kong Genetic Background: involves: 129P2/OlaHsd
MP:0009643	abnormal urine homeostasis	"anomaly in the processes involved in the maintenance of an internal equilibrium of various functions and chemical or protein composition of the urine" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Pctp^tm1Bor/Pctp^tm1Bor Genetic Background: involves: 129P2/OlaHsd * FVB/NJ
MP:0009652	abnormal palatal rugae	"any structural anomaly in the transversal ridges that develop on the secondary (hard) palate" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]	Show Allelic Composition: Cdk2^tm2Sgo/Cdk2^tm2Sgo,Cdk4^tm2.1Bbd/Cdk4^tm2.1Bbd,Polr2a^{tm1(cre/ERT2)Bbd}/? Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL Allelic Composition: Ednrb^s-36Pub/Ednrb^s-36Pub Genetic Background: B6.Cg-Ednrb^s-36Pub
MP:0009655	abnormal secondary palate development	"any anomaly in the formation of the part of the palate that is formed during embryonic development when palatal projections from the inner part of the maxillary processes emerge, extend and elevate into a horizontal position above the tongue" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator", PMID:16942766]	Show Allelic Composition: Ednrb^s-36Pub/Ednrb^s-36Pub Genetic Background: B6.Cg-Ednrb^s-36Pub
MP:0009886	failure of palatal shelf elevation	"the palatal shelves fail to move from a vertical position in the orofacial cavity to a horizontal apposition above the developing tongue" [PMID:16680722]	Show Allelic Composition: Ednrb^s-36Pub/Ednrb^s-36Pub Genetic Background: B6.Cg-Ednrb^s-36Pub
MP:0009890	cleft secondary palate	"congenital fissure of the tissues normally uniting to form the secondary palate" [PMID:16680722]	Show Allelic Composition: Cdk2^tm2Sgo/Cdk2^tm2Sgo,Cdk4^tm2.1Bbd/Cdk4^tm2.1Bbd,Polr2a^{tm1(cre/ERT2)Bbd}/? Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL Allelic Composition: Ednrb^s-36Pub/Ednrb^s-36Pub Genetic Background: B6.Cg-Ednrb^s-36Pub Allelic Composition: Ednrb^s-36Pub/Ednrb^s-36Pub,Tg(Spry2)2Tpo/0 Genetic Background: B6.Cg-Ednrb^s-36Pub Tg(Spry2)2Tpo Allelic Composition: Ednrb^s-36Pub/Ednrb^s-36Pub,Tg(Spry2)69Tpo/0 Genetic Background: B6.Cg-Ednrb^s-36Pub Tg(Spry2)69Tpo
MP:0009891	abnormal palate bone morphology	"any structural anomaly of the maxillary or palatine shelves that comprise the bones of the hard palate" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Ednrb^s-36Pub/Ednrb^s-36Pub,Tg(Spry2)2Tpo/0 Genetic Background: B6.Cg-Ednrb^s-36Pub Tg(Spry2)2Tpo Allelic Composition: Ednrb^s-36Pub/Ednrb^s-36Pub,Tg(Spry2)69Tpo/0 Genetic Background: B6.Cg-Ednrb^s-36Pub Tg(Spry2)69Tpo
MP:0009898	maxillary shelf hypoplasia	"underdevelopment, usually due to a deficiency in the number of cells, of the bony projection of the maxilla that normally fuses with palatine shelf to form secondary (hard) palate" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Ednrb^s-36Pub/Ednrb^s-36Pub Genetic Background: B6.Cg-Ednrb^s-36Pub Allelic Composition: Ednrb^s-36Pub/Ednrb^s-36Pub,Tg(Spry2)2Tpo/0 Genetic Background: B6.Cg-Ednrb^s-36Pub Tg(Spry2)2Tpo Allelic Composition: Ednrb^s-36Pub/Ednrb^s-36Pub,Tg(Spry2)69Tpo/0 Genetic Background: B6.Cg-Ednrb^s-36Pub Tg(Spry2)69Tpo
MP:0010016	variable depigmentation	"absence or loss of normal pigment in the skin in various and irregular patterns" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]	Show Allelic Composition: Apoe^tm1Lmh/Apoe⁺ Genetic Background: involves: 129S7/SvEvBrd * C57BL/6 Allelic Composition: Ednrb^s/Ednrb^s Genetic Background: Not Specified
MP:0010155	abnormal intestine physiology	"any functional anomaly of the digestive tube passing from the stomach to the anus" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Slc26a4^loop/Slc26a4^loop Genetic Background: C3HeB/FeJ-Slc26a4^loop
MP:0010275	increased melanoma incidence	"greater than the expected number of malignant neoplasms, derived from melanocytes and occuring in pigmented tissues, in a specific population in a given time period" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]	Show Allelic Composition: Ednrb^tm1Ywa/Ednrb⁺,Tg(Mt1-RET)304Ina/0 Genetic Background: involves: 129S7/SvEvBrd * BALB/c * C57BL/6
MP:0010741	abnormal melanocyte proliferation	"anomaly in the ability of the a melanocyte cell population to undergo expansion by cell division" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Ednrb^s-l/Ednrb^s-l Genetic Background: involves: C57BL/6J * SSL/Le
MP:0011083	complete lethality at weaning	"premature death at weaning age of all organisms of a given genotype in a population, often due to the inability to make the transition to solid food" [MGI:csmith]	Show Allelic Composition: Ednrb^s-Btlr/Ednrb^s-Btlr Genetic Background: C57BL/6J-Ednrb^s-Btlr Allelic Composition: Ednrb^tm1.1Nrd/Ednrb^tm1.1Nrd Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
MP:0011085	complete postnatal lethality	"premature death anytime between the neonatal period and weaning age of all organisms of a given genotype in a population (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith]	Show Allelic Composition: Ednrb^s-17FrS/Ednrb^s-17FrS Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Ednrb^s-27Pub/Ednrb^s-27Pub Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Ednrb^tm1.1Yko/Ednrb^tm1.1Yko Genetic Background: involves: 129P2/OlaHsd * Bkl:BKW * C57BL/6 * SJL Allelic Composition: Ednrb^s-12MNURn/Ednrb^s-12MNURn Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Ednrb^s-3CHLo/Ednrb^s-3CHLo Genetic Background: involves: 101/Rl * C3H/Rl
MP:0011086	partial postnatal lethality	"the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms anytime between the neonatal period and weaning age (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith]	Show Allelic Composition: Ednrb^s-1Chlc/Ednrb^s-1Chlc Genetic Background: involves: 101/Rl * C3H/Rl
MP:0011087	complete neonatal lethality	"death of all organisms of a given genotype in a population within the neonatal period after birth (Mus: P0)" [MGI:csmith]	Show Allelic Composition: Ednrb^s-15DttMb/Ednrb^s-15DttMb Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Ednrb^s-24Pub/Ednrb⁺,Mycbp2^m274-4Tpo/Mycbp2⁺ Genetic Background: involves: 101/Rl * C3H/Rl * C57BL/6J * SSL/LeJ Allelic Composition: Ednrb^s-36Pub/Ednrb^s-36Pub Genetic Background: involves: 101/Rl * C3H/Rl
MP:0011091	complete prenatal lethality	"death of all organisms of a given genotype in a population between fertilization and birth (Mus: approximately E18.5)" [MGI:csmith]	Show Allelic Composition: Myo5a^d-nBtlr/Myo5a^d-nBtlr Genetic Background: C57BL/6J-Myo5a^d-nBtlr Allelic Composition: Ednrb^s-1Acrg/Ednrb^s-1Acrg Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Ednrb^s-1MLPf/Ednrb^s-1MLPf Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Ednrb^s-1Pu/Ednrb^s-1Pu Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Ednrb^s-1XMLP/Ednrb^s-1XMLP Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Ednrb^s-1XMLPc/Ednrb^s-1XMLPc Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Ednrb^s-27Pu/Ednrb^s-27Pu Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Ednrb^s-29Pub/Ednrb^s-29Pub Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Ednrb^s-2Etopc/Ednrb^s-2Etopc Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Ednrb^s-2MLPl/Ednrb^s-2MLPl Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Ednrb^s-31Pub/Ednrb^s-31Pub Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Ednrb^s-3Etopf/Ednrb^s-3Etopf Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Ednrb^s-48UThc/Ednrb^s-48UThc Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Ednrb^s-4Blec/Ednrb^s-4Blec Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Ednrb^s-52Pub/Ednrb^s-52Pub Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Ednrb^s-9ThW/Ednrb^s-9ThW Genetic Background: involves: 101/Rl * C3H/Rl
MP:0011092	complete embryonic lethality	"death of all organisms of a given genotype in a population within the embryonic period prior to organogenesis (Mus: prior to E14)" [MGI:csmith]	Show Allelic Composition: Ednrb^s-24Pub/Ednrb⁺,Mycbp2^m274-4Tpo/Mycbp2⁺ Genetic Background: involves: 101/Rl * C3H/Rl * C57BL/6J * SSL/LeJ
MP:0011096	complete embryonic lethality before somite formation	"death of all organisms of a given genotype in a population between the point of implantation and somite formation (Mus: E4.5 to less than E8)" [MGI:csmith]	Show Allelic Composition: Ednrb^s-24Pub/Ednrb⁺,Mycbp2^m274-4Tpo/Mycbp2⁺ Genetic Background: involves: 101/Rl * C3H/Rl * C57BL/6J * SSL/LeJ
MP:0011099	complete lethality throughout fetal growth and development	"death of all organisms of a given genotype in a population between the completion of organogenesis and birth (Mus: E14 to approximately E18.5)" [MGI:csmith]	Show Allelic Composition: Ednrb^s-24Pub/Ednrb⁺,Mycbp2^m274-4Tpo/Mycbp2⁺ Genetic Background: involves: 101/Rl * C3H/Rl * C57BL/6J * SSL/LeJ
MP:0011100	complete preweaning lethality	"death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]	Show Allelic Composition: Ednrb^s/Ednrb^s-17FrS Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Ednrb^s-24Pub/Ednrb^s-24Pub Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Ednrb^s-2CHLd/Ednrb^s-2CHLd Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Ednrb^s-24Pub/Ednrb⁺,m251-2Tpo/m251-2Tpo⁺ Genetic Background: involves: 101/Rl * C3H/Rl * C57BL/6J * SSL/LeJ Allelic Composition: Ednrb^s-24Pub/Ednrb⁺,m283-1Tpo/m283-1Tpo⁺ Genetic Background: involves: 101/Rl * C3H/Rl * C57BL/6J * SSL/LeJ Allelic Composition: Ednrb^s-24Pub/Ednrb^s-24Pub,m289-5Tpo/m289-5Tpo⁺ Genetic Background: involves: 101/Rl * C3H/Rl * C57BL/6J * SSL/LeJ Allelic Composition: Ednrb^s-4Chlc/Ednrb^s-4Chlc Genetic Background: involves: 101/Rl * C3H/Rl Allelic Composition: Ednrb^s-4Pub/Ednrb^s-4Pub Genetic Background: involves: 101/Rl * C3H/Rl
MP:0011110	partial preweaning lethality	"the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]	Show Allelic Composition: Ednrb^s-l/Ednrb^s-l Genetic Background: involves: C3H/HeJ * C57BL/6
MP:0011494	abnormal pigmentation pattern	"hair and/or skin coloration shows specific and consistent deviations from an expected display" [MGI:llw2]	Show Allelic Composition: Ednrb^s-l/Ednrb^s-l Genetic Background: involves: C3H/HeJ * C57BL/6 Allelic Composition: Ednrb^s-l/Ednrb^s-l Genetic Background: involves: C57BL/6J * SSL/Le
MP:0013006	abnormal enteric neural crest cell migration	"any anomaly in the migratory path or behavior of the neural crest cells (NCCs) that arise predominantly from the vagal (neck) region of the neural tube (vagal neural crest), adjacent to somites 1-7, and migrate rostro-caudally along the gastrointestinal tract to form two ganglionated plexuses of neurons and glial cells that comprise the enteric nervous system (ENS); a smaller proportion of ENCCs come from the sacral neural crest, caudal to somite 28, and migrate caudo-rostrally to colonize the distal gut; NCCs are termed enteric neural crest-derived cells upon entering the foregut at E9-9.5 in mice (after 4 weeks gestation in humans) and the colonization process is complete by E15.5 (after 7 weeks gestation in humans)" [MGI:anna, PMID:17514199]	Show Allelic Composition: Ednrb^tm1Nrd/Ednrb^tm1Nrd,Gt(ROSA)26Sor^tm1(EYFP)Cos/Gt(ROSA)26Sor⁺,H2afv^{Tg(Wnt1-cre)11Rth}/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA/J
MP:0013404	decreased circulating lactate level	"reduced amount of lactate in the blood which is produced from pyruvate by lactate dehydrogenase" [MPD:Molly]	Show Allelic Composition: Ednrb^tm1.1Nrd/Ednrb⁺ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
MP:0013701	abnormal mature B cell number	"anomaly in the number of the mature form of B cells, a type of lymphocyte whose defining characteristic is the expression of an immunoglobulin complex" [CL:0000785]	Show Allelic Composition: Ednrb^tm1Nrd/Ednrb^tm1Nrd,Gt(ROSA)26Sor^{tm14(CAG-tdTomato)Hze}/Gt(ROSA)26Sor⁺,H2afv^{Tg(Wnt1-cre)11Rth}/0 Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6 * CBA/J
MP:0013795	abnormal colon goblet cell morphology	"any structural anomaly of the glandular simple columnar epithelial cell found in the mucosal lining of the colon, whose primary function is to secrete gel-forming mucins, the major components of mucus" [MGI:Anna, PMID:25872481]	Show Allelic Composition: Slc26a4^loop/Slc26a4^loop Genetic Background: C3HeB/FeJ-Slc26a4^loop

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		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr

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