ENSMUSG00000019872


Mus musculus

Features
Gene ID: ENSMUSG00000019872
  
Biological name :Smpdl3a
  
Synonyms : P70158 / Smpdl3a / sphingomyelin phosphodiesterase, acid-like 3A
  
Possible biological names infered from orthology : Q92484
  
Species: Mus musculus
  
Chr. number: 10
Strand: 1
Band: B4
Gene start: 57794335
Gene end: 57811830
  
Corresponding Affymetrix probe sets: 10363231 (MoGene1.0st)   1416635_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000122041
Ensembl peptide - ENSMUSP00000020022
NCBI entrez gene - 57319     See in Manteia.
MGI - MGI:1931437
RefSeq - NM_020561
RefSeq Peptide - NP_065586
swissprot - D3Z1B4
swissprot - P70158
Ensembl - ENSMUSG00000019872
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 smpdl3aENSDARG00000053119Danio rerio
 ENSGALG00000030275Gallus gallus
 Q92484ENSG00000172594Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P58242 / Smpdl3b / sphingomyelin phosphodiesterase, acid-like 3B / Q92485*ENSMUSG0000002888537
Smpd1 / Q04519 / sphingomyelin phosphodiesterase 1, acid lysosomal / P17405* / sphingomyelin phosphodiesterase 1*ENSMUSG0000003704928


Protein motifs (from Interpro)
Interpro ID Name
 IPR004843  Calcineurin-like phosphoesterase domain, ApaH type
 IPR017064  Acid sphingomyelinase-like phosphodiesterase, predicted
 IPR029052  Metallo-dependent phosphatase-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006685 sphingomyelin catabolic process IEA
 biological_processGO:0008150 biological_process ND
 biological_processGO:0009143 nucleoside triphosphate catabolic process IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space ISO
 molecular_functionGO:0004767 sphingomyelin phosphodiesterase activity IEA
 molecular_functionGO:0008081 phosphoric diester hydrolase activity IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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