ENSMUSG00000020062


Mus musculus

Features
Gene ID: ENSMUSG00000020062
  
Biological name :Slc5a8
  
Synonyms : Q8BYF6 / Slc5a8 / Sodium-coupled monocarboxylate transporter 1
  
Possible biological names infered from orthology : Q8N695 / solute carrier family 5 member 8
  
Species: Mus musculus
  
Chr. number: 10
Strand: 1
Band: C1
Gene start: 88885992
Gene end: 88929515
  
Corresponding Affymetrix probe sets: 10365640 (MoGene1.0st)   1425606_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000020255
NCBI entrez gene - 216225     See in Manteia.
MGI - MGI:2384916
RefSeq - NM_145423
RefSeq Peptide - NP_663398
swissprot - Q8BYF6
Ensembl - ENSMUSG00000020062
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 slc5a8ENSDARG00000087120Danio rerio
 SLC5A8ENSGALG00000011633Gallus gallus
 Q8N695ENSG00000256870Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q49B93 / Slc5a12 / solute carrier family 5 (sodium/glucose cotransporter), member 12 / Q1EHB4* / solute carrier family 5 member 12*ENSMUSG0000004164452
Slc5a5 / solute carrier family 5 member 5 / Q92911*ENSMUSG0000000079248
Q5U4D8 / Slc5a6 / Sodium-dependent multivitamin transporter / Q9Y289* / solute carrier family 5 member 6*ENSMUSG0000000664143
Q8K0E3 / Slc5a11 / Sodium/myo-inositol cotransporter 2 / Q8WWX8* / solute carrier family 5 member 11*ENSMUSG0000003076923
Slc5a1 / solute carrier family 5 (sodium/glucose cotransporter), member 1 / P13866* / solute carrier family 5 member 1*ENSMUSG0000001103422
Q8VDT1 / Slc5a9 / Sodium/glucose cotransporter 4 / Q2M3M2* / solute carrier family 5 member 9*ENSMUSG0000002854421
Q5SWY8 / Slc5a10 / Sodium/glucose cotransporter 5 / A0PJK1* / solute carrier family 5 member 10*ENSMUSG0000004237121
Slc5a4b / solute carrier family 5 (neutral amino acid transporters, system A), member 4b / Q9NY91* / SLC5A4* / solute carrier family 5 member 4*ENSMUSG0000002022621
Slc5a4a / Q9NY91* / SLC5A4* / solute carrier family 5 member 4*ENSMUSG0000002022920
Q9JKZ2 / Slc5a3 / Sodium/myo-inositol cotransporter / P53794* / solute carrier family 5 member 3*ENSMUSG0000008977420
Q923I7 / Slc5a2 / Sodium/glucose cotransporter 2 / P31639* / solute carrier family 5 member 2*ENSMUSG0000003078120
Gm5134ENSMUSG0000003325518


Protein motifs (from Interpro)
Interpro ID Name
 IPR001734  Sodium/solute symporter


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006814 sodium ion transport IEA
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0055085 transmembrane transport IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0016324 apical plasma membrane IEA
 molecular_functionGO:0015293 symporter activity IEA
 molecular_functionGO:0022857 transmembrane transporter activity IEA


Pathways (from Reactome)
Pathway description
Nicotinamide salvaging
Organic anion transporters


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002044 colonic adenoma "benign tumors of the large intestine" [J:38772]
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Allelic Composition: Bmp5se/Bmp5se,Bmp6tm1Rob/Bmp6tm1Rob
Genetic Background: involves: 129S/SvEv

 MP:0005310 abnormal salivary gland physiology "anomalous function of any of the glands in the mouth that secrete saliva" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Tg(Pomc-MAPT/Topaz)1Rck/0,Ucp2Gt(S20-3G1)Sor/Ucp2Gt(S20-3G1)Sor
Genetic Background: involves: C57BL/6 * CBA

 MP:0009643 abnormal urine homeostasis "anomaly in the processes involved in the maintenance of an internal equilibrium of various functions and chemical or protein composition of the urine" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Tg(Pomc-MAPT/Topaz)1Rck/0,Ucp2Gt(S20-3G1)Sor/Ucp2Gt(S20-3G1)Sor
Genetic Background: involves: C57BL/6 * CBA

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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