ENSMUSG00000020437


Mus musculus

Features
Gene ID: ENSMUSG00000020437
  
Biological name :Myo1g
  
Synonyms : Myo1g / Q5SUA5 / Unconventional myosin-Ig
  
Possible biological names infered from orthology : B0I1T2 / myosin IG
  
Species: Mus musculus
  
Chr. number: 11
Strand: -1
Band: A1
Gene start: 6506548
Gene end: 6520965
  
Corresponding Affymetrix probe sets: 10384154 (MoGene1.0st)   1427892_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000003459
Ensembl peptide - ENSMUSP00000122438
Ensembl peptide - ENSMUSP00000122356
Ensembl peptide - ENSMUSP00000120975
NCBI entrez gene - 246177     See in Manteia.
MGI - MGI:1927091
RefSeq - XM_006514702
RefSeq - NM_178440
RefSeq - XM_006514700
RefSeq Peptide - NP_848534
swissprot - D6RHL4
swissprot - Q5SUA5
swissprot - A8Y5I5
swissprot - D6RGA2
Ensembl - ENSMUSG00000020437
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 MYO1GENSDARG00000036104Danio rerio
 MYO1GENSGALG00000005644Gallus gallus
 MYO1GENSG00000136286Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Myo1d / Q5SYD0 / Unconventional myosin-Id / O94832* / myosin ID*ENSMUSG0000003544159
Myo1h / Q9D6A1 / Unconventional myosin-Ih / Q8N1T3* / myosin IH*ENSMUSG0000006695239
Myo1c / Q9WTI7 / Unconventional myosin-Ic / O00159* / myosin IC*ENSMUSG0000001777438
Myo1a / O88329 / Unconventional myosin-Ia / Q9UBC5* / myosin IA*ENSMUSG0000002540138
Myo1b / P46735 / myosin IB / O43795*ENSMUSG0000001841737
Myo1f / myosin IF / O00160*ENSMUSG0000002430033
Myo1e / E9Q634 / Unconventional myosin-Ie / Q12965* / myosin IE*ENSMUSG0000003222032
Myo15 / Q9QZZ4 / Unconventional myosin-XV / MYO15A* / Q9UKN7* / myosin XVA*ENSMUSG0000004267831
Myo15b / myosin XVBENSMUSG0000003442725


Protein motifs (from Interpro)
Interpro ID Name
 IPR001609  Myosin head, motor domain
 IPR010926  Class I myosin tail homology domain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR036072  Class I myosin, motor domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002250 adaptive immune response IEA
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0002456 T cell mediated immunity IMP
 biological_processGO:0006887 exocytosis IMP
 biological_processGO:0006909 phagocytosis IMP
 biological_processGO:0007018 microtubule-based movement IEA
 biological_processGO:0031589 cell-substrate adhesion IMP
 biological_processGO:0038096 Fc-gamma receptor signaling pathway involved in phagocytosis IMP
 biological_processGO:0071976 cell gliding IMP
 biological_processGO:0072678 T cell migration IMP
 cellular_componentGO:0001891 phagocytic cup IEA
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0005902 microvillus IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016459 myosin complex IEA
 cellular_componentGO:0030027 lamellipodium IDA
 cellular_componentGO:0030175 filopodium IDA
 cellular_componentGO:0031256 leading edge membrane IDA
 cellular_componentGO:0042995 cell projection IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003774 motor activity IEA
 molecular_functionGO:0003777 microtubule motor activity IEA
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0005516 calmodulin binding IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0005546 phosphatidylinositol-4,5-bisphosphate binding IDA
 molecular_functionGO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding IDA
 molecular_functionGO:0008017 microtubule binding IEA
 molecular_functionGO:0008289 lipid binding IEA
 molecular_functionGO:0043325 phosphatidylinositol-3,4-bisphosphate binding IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002444 abnormal T cell physiology "anomalous response of T lymphocytes" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Myoz2tm1Eno/Myoz2+,Tg(Myh6-MYOZ2*I246M)#Ajm/0
Genetic Background: involves: 129/Sv * FVB/N

Allelic Composition: Myo1gtm1.2Mfk/Myo1gtm1.2Mfk,Tg(TcraTcrb)1100Mjb/0
Genetic Background: involves: C57BL/6 * FVB/N * SJL

 MP:0002459 abnormal B cell physiology "abnormal function of B lymphocytes" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Slc39a5tm1Gka/Slc39a5tm1Gka,Tg(Cela1-cre/ERT)1Lgdn/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0005014 increased B cell number "greater than normal B cell numbers" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Slc39a5tm1Gka/Slc39a5tm1Gka,Tg(Cela1-cre/ERT)1Lgdn/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0005017 decreased B cell number "fewer than normal B cell numbers" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Slc39a5tm1Gka/Slc39a5tm1Gka,Tg(Cela1-cre/ERT)1Lgdn/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0008561 decreased tumor necrosis factor secretion "reduction in the production or release of a serum glycoprotein produced by activated macrophages and NK cells and involved in initiating local inflammatory responses, particularly by its action on the endothelium of local blood vessels; its actions result in increased vascular permeability and induction of expression of adhesion molecules on the endothelium" [ISBN:0-8153-1691-7 "Immunobiology, The Immune System in Health and Disease", MESH:D12.644.276.374.500.800]
Show

Allelic Composition: Slc39a5tm1Gka/Slc39a5tm1Gka,Tg(Cela1-cre/ERT)1Lgdn/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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