ENSMUSG00000066952


Mus musculus

Features
Gene ID: ENSMUSG00000066952
  
Biological name :Myo1h
  
Synonyms : Myo1h / Q9D6A1 / Unconventional myosin-Ih
  
Possible biological names infered from orthology : myosin IH / Q8N1T3
  
Species: Mus musculus
  
Chr. number: 5
Strand: 1
Band: F
Gene start: 114289166
Gene end: 114365357
  
Corresponding Affymetrix probe sets: 10524515 (MoGene1.0st)   1450543_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000118824
Ensembl peptide - ENSMUSP00000144682
Ensembl peptide - ENSMUSP00000144492
Ensembl peptide - ENSMUSP00000144133
Ensembl peptide - ENSMUSP00000144110
Ensembl peptide - ENSMUSP00000132905
NCBI entrez gene - 231646     See in Manteia.
MGI - MGI:1914674
RefSeq - XM_011248195
RefSeq - NM_001164573
RefSeq Peptide - NP_001158045
swissprot - A0A0J9YUC4
swissprot - B7ZMY2
swissprot - A0A0J9YUE0
swissprot - Q9D6A1
swissprot - A0A0J9YV53
swissprot - E9PWM9
Ensembl - ENSMUSG00000066952
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 myo1haENSDARG00000061968Danio rerio
 myo1hbENSDARG00000078603Danio rerio
 MYO1HENSGALG00000005122Gallus gallus
 MYO1HENSG00000174527Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Myo1c / Q9WTI7 / Unconventional myosin-Ic / O00159* / myosin IC*ENSMUSG0000001777461
Myo1b / P46735 / myosin IB / O43795*ENSMUSG0000001841741
Myo1a / O88329 / Unconventional myosin-Ia / Q9UBC5* / myosin IA*ENSMUSG0000002540140
Myo1d / Q5SYD0 / Unconventional myosin-Id / O94832* / myosin ID*ENSMUSG0000003544139
Myo1g / Q5SUA5 / Unconventional myosin-Ig / B0I1T2* / myosin IG*ENSMUSG0000002043739
Myo1e / E9Q634 / Unconventional myosin-Ie / Q12965* / myosin IE*ENSMUSG0000003222035
Myo1f / myosin IF / O00160*ENSMUSG0000002430035
Myo15 / Q9QZZ4 / Unconventional myosin-XV / MYO15A* / Q9UKN7* / myosin XVA*ENSMUSG0000004267832
Myo15b / myosin XVBENSMUSG0000003442727


Protein motifs (from Interpro)
Interpro ID Name
 IPR000048  IQ motif, EF-hand binding site
 IPR001609  Myosin head, motor domain
 IPR010926  Class I myosin tail homology domain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR036072  Class I myosin, motor domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007018 microtubule-based movement IEA
 cellular_componentGO:0016459 myosin complex IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003774 motor activity IEA
 molecular_functionGO:0003777 microtubule motor activity IEA
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008017 microtubule binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001516 abnormal motor coordination/ balance "altered ability of an animal to maintain skillful and effective interaction of movements or maintenance of equilibrium" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Mmachctm1.1(NCOM)Mfgc/Mmachctm1.1(NCOM)Mfgc
Genetic Background: C57BL/6N-Mmachctm1.1(NCOM)Mfgc/Tcp

 MP:0003961 decreased lean body mass "less than average fat-free physical bulk or volume of the body including all its components except adipose tissue" [honda:Hiraoki Onda, Mouse GEnome Informatics Curator]
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Allelic Composition: Mmachctm1.1(NCOM)Mfgc/Mmachctm1.1(NCOM)Mfgc
Genetic Background: C57BL/6N-Mmachctm1.1(NCOM)Mfgc/Tcp

 MP:0011100 complete preweaning lethality "death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
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Allelic Composition: Myo18atm1b(KOMP)Wtsi/Myo18a+
Genetic Background: C57BL/6N-Myo18atm1b(KOMP)Wtsi/Ucd

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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