ENSMUSG00000020495


Mus musculus

Features
Gene ID: ENSMUSG00000020495
  
Biological name :Smg8
  
Synonyms : Protein SMG8 / Q8VE18 / Smg8
  
Possible biological names infered from orthology : Q8ND04 / SMG8, nonsense mediated mRNA decay factor
  
Species: Mus musculus
  
Chr. number: 11
Strand: -1
Band: C
Gene start: 87077732
Gene end: 87086774
  
Corresponding Affymetrix probe sets: 10389601 (MoGene1.0st)   1427737_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000020801
Ensembl peptide - ENSMUSP00000119011
NCBI entrez gene - 74133     See in Manteia.
MGI - MGI:1921383
RefSeq - NM_024262
RefSeq Peptide - NP_077224
swissprot - Q8VE18
swissprot - Q99LS6
Ensembl - ENSMUSG00000020495
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 smg8ENSDARG00000061378Danio rerio
 ENSGALG00000005093Gallus gallus
 SMG8ENSG00000167447Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR019354  Smg8/Smg9
 IPR028802  Protein SMG8


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay IEA
 biological_processGO:0045859 regulation of protein kinase activity IEA
 cellular_componentGO:0005575 cellular_component ND
 molecular_functionGO:0003674 molecular_function ND


Pathways (from Reactome)
Pathway description
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000002210 Smg9 / Q9DB90 / Protein SMG9 / Q9H0W8* / SMG9, nonsense mediated mRNA decay factor*  / complex
 ENSMUSG00000030655 Smg1 / Q8BKX6 / Serine/threonine-protein kinase SMG1 / Q96Q15* / SMG1, nonsense mediated mRNA decay associated PI3K related kinase*  / complex
 ENSMUSG00000058301 Upf1 / Q9EPU0 / UPF1 regulator of nonsense transcripts homolog (yeast) / Q92900* / UPF1, RNA helicase and ATPase*  / complex






 

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contact: otassy@igbmc.fr