ENSG00000167447


Homo sapiens

Features
Gene ID: ENSG00000167447
  
Biological name :SMG8
  
Synonyms : Q8ND04 / SMG8 / SMG8, nonsense mediated mRNA decay factor
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: 1
Band: q22
Gene start: 59209400
Gene end: 59215247
  
Corresponding Affymetrix probe sets: 218514_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000462931
Ensembl peptide - ENSP00000463175
Ensembl peptide - ENSP00000300917
Ensembl peptide - ENSP00000438748
Ensembl peptide - ENSP00000462119
NCBI entrez gene - 55181     See in Manteia.
OMIM - 613175
RefSeq - NM_018149
RefSeq Peptide - NP_060619
swissprot - J3KTD7
swissprot - J3QKP6
swissprot - Q8ND04
Ensembl - ENSG00000167447
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 smg8ENSDARG00000061378Danio rerio
 ENSGALG00000005093Gallus gallus
 Smg8ENSMUSG00000020495Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
AC099850.2ENSG000002653038


Protein motifs (from Interpro)
Interpro ID Name
 IPR019354  Smg8/Smg9
 IPR028802  Protein SMG8


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay TAS
 biological_processGO:0045859 regulation of protein kinase activity IMP
 cellular_componentGO:0005575 cellular_component ND
 cellular_componentGO:0005829 cytosol TAS
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000005007 UPF1 / Q92900 / UPF1, RNA helicase and ATPase  / complex / reaction
 ENSG00000105771 SMG9 / Q9H0W8 / SMG9, nonsense mediated mRNA decay factor  / complex
 ENSG00000157106 SMG1 / Q96Q15 / SMG1, nonsense mediated mRNA decay associated PI3K related kinase  / complex






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr