ENSMUSG00000021051


Mus musculus

Features
Gene ID: ENSMUSG00000021051
  
Biological name :Ppp2r5e
  
Synonyms : Ppp2r5e / protein phosphatase 2, regulatory subunit B, epsilon / Q61151
  
Possible biological names infered from orthology : protein phosphatase 2 regulatory subunit Bepsilon / Q16537
  
Species: Mus musculus
  
Chr. number: 12
Strand: -1
Band: C3
Gene start: 75450881
Gene end: 75596245
  
Corresponding Affymetrix probe sets: 10401007 (MoGene1.0st)   1428461_at (Mouse Genome 430 2.0 Array)   1428462_at (Mouse Genome 430 2.0 Array)   1428463_a_at (Mouse Genome 430 2.0 Array)   1439401_x_at (Mouse Genome 430 2.0 Array)   1452788_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000151624
Ensembl peptide - ENSMUSP00000151905
Ensembl peptide - ENSMUSP00000021447
Ensembl peptide - ENSMUSP00000151427
NCBI entrez gene - 26932     See in Manteia.
MGI - MGI:1349473
RefSeq - XM_006515925
RefSeq - XM_006515926
RefSeq - XM_006515927
RefSeq - NM_012024
RefSeq Peptide - NP_036154
swissprot - Q3UZJ4
swissprot - A0A1W2P7D8
swissprot - A0A1W2P838
swissprot - Q61151
Ensembl - ENSMUSG00000021051
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ppp2r5eaENSDARG00000015474Danio rerio
 ppp2r5ebENSDARG00000069118Danio rerio
 PPP2R5EENSGALG00000011840Gallus gallus
 Q16537ENSG00000154001Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q6PD03 / Ppp2r5a / protein phosphatase 2, regulatory subunit B, alpha / Q15172* / protein phosphatase 2 regulatory subunit Balpha*ENSMUSG0000002662677
Q6PD28 / Ppp2r5b / protein phosphatase 2, regulatory subunit B, beta / Q15173* / protein phosphatase 2 regulatory subunit Bbeta*ENSMUSG0000002477772
Ppp2r5d / protein phosphatase 2, regulatory subunit B, delta / Q14738* / protein phosphatase 2 regulatory subunit Bdelta*ENSMUSG0000005940969
Q60996 / Ppp2r5c / protein phosphatase 2, regulatory subunit B, gamma / Q13362* / protein phosphatase 2 regulatory subunit Bgamma*ENSMUSG0000001784365


Protein motifs (from Interpro)
Interpro ID Name
 IPR002554  Protein phosphatase 2A, regulatory B subunit, B56
 IPR011989  Armadillo-like helical
 IPR016024  Armadillo-type fold


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0043666 regulation of phosphoprotein phosphatase activity IEA
 cellular_componentGO:0000159 protein phosphatase type 2A complex IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 molecular_functionGO:0005488 binding IEA
 molecular_functionGO:0019888 protein phosphatase regulator activity IEA


Pathways (from Reactome)
Pathway description
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
Degradation of beta-catenin by the destruction complex
Beta-catenin phosphorylation cascade
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
CTLA4 inhibitory signaling
Disassembly of the destruction complex and recruitment of AXIN to the membrane
RHO GTPases Activate Formins
RAF activation
Negative regulation of MAPK pathway
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling
Mitotic Prometaphase


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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