ENSMUSG00000021111


Mus musculus

Features
Gene ID: ENSMUSG00000021111
  
Biological name :Papola
  
Synonyms : Papola / Poly(A) polymerase alpha / Q61183
  
Possible biological names infered from orthology : P51003
  
Species: Mus musculus
  
Chr. number: 12
Strand: 1
Band: E
Gene start: 105784694
Gene end: 105838944
  
Corresponding Affymetrix probe sets: 10398147 (MoGene1.0st)   1424216_a_at (Mouse Genome 430 2.0 Array)   1424217_at (Mouse Genome 430 2.0 Array)   1427544_a_at (Mouse Genome 430 2.0 Array)   1444015_at (Mouse Genome 430 2.0 Array)   1455836_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000128402
Ensembl peptide - ENSMUSP00000132353
Ensembl peptide - ENSMUSP00000131729
Ensembl peptide - ENSMUSP00000131725
Ensembl peptide - ENSMUSP00000131668
Ensembl peptide - ENSMUSP00000130798
Ensembl peptide - ENSMUSP00000130714
Ensembl peptide - ENSMUSP00000130687
Ensembl peptide - ENSMUSP00000128908
Ensembl peptide - ENSMUSP00000021535
Ensembl peptide - ENSMUSP00000105527
Ensembl peptide - ENSMUSP00000125818
Ensembl peptide - ENSMUSP00000125898
Ensembl peptide - ENSMUSP00000126275
NCBI entrez gene - 18789     See in Manteia.
MGI - MGI:109301
RefSeq - XM_017314994
RefSeq - NM_011112
RefSeq - XM_006515592
RefSeq - XM_006515593
RefSeq - XM_006515594
RefSeq - XM_006515595
RefSeq - XM_006515596
RefSeq - XM_017314992
RefSeq - XM_017314993
RefSeq Peptide - NP_035242
RefSeq Peptide - NP_001334369
swissprot - E9QAN5
swissprot - E9QAY4
swissprot - Q61183
swissprot - E9QAN2
swissprot - E9Q5Z1
swissprot - E9PZR3
swissprot - E9PWC8
swissprot - E9PVN7
swissprot - A0A0R4J244
swissprot - F6VTN8
swissprot - F7CXD5
swissprot - F7AB38
swissprot - F7DC29
Ensembl - ENSMUSG00000021111
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 papolaENSDARG00000009585Danio rerio
 PAPOLAENSGALG00000033099Gallus gallus
 P51003ENSG00000090060Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Papolb / poly(A) polymerase beta / Q9NRJ5*ENSMUSG0000007481774
Papolg / Q6PCL9 / poly(A) polymerase gamma / Q9BWT3*ENSMUSG0000002027357


Protein motifs (from Interpro)
Interpro ID Name
 IPR002934  Polymerase, nucleotidyl transferase domain
 IPR007010  Poly(A) polymerase, RNA-binding domain
 IPR007012  Poly(A) polymerase, central domain
 IPR011068  Nucleotidyltransferase, class I-like, C-terminal
 IPR014492  Poly(A) polymerase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006378 mRNA polyadenylation ISS
 biological_processGO:0006397 mRNA processing IEA
 biological_processGO:0031123 RNA 3"-end processing IEA
 biological_processGO:0031440 regulation of mRNA 3"-end processing ISS
 biological_processGO:0043631 RNA polyadenylation IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm ISO
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0000287 magnesium ion binding ISS
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0004652 polynucleotide adenylyltransferase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016779 nucleotidyltransferase activity IEA
 molecular_functionGO:0030145 manganese ion binding ISS
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Cleavage of Growing Transcript in the Termination Region
mRNA Splicing - Major Pathway
mRNA 3-end processing
Processing of Intronless Pre-mRNAs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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