Manteia

ENSMUSG00000021240

Mus musculus

Features

Gene ID:	ENSMUSG00000021240

Biological name :	Abcd4

Synonyms :	Abcd4 / ATP-binding cassette, sub-family D (ALD), member 4 / O89016

Possible biological names infered from orthology :	ATP binding cassette subfamily D member 4 / O14678

Species:	Mus musculus

Chr. number:	12
Strand:	-1
Band:	D1
Gene start:	84601464
Gene end:	84617413

Corresponding Affymetrix probe sets:	10401488 (MoGene1.0st) 1419572_a_at (Mouse Genome 430 2.0 Array) 1427829_at (Mouse Genome 430 2.0 Array)

Cross references:	Ensembl peptide - ENSMUSP00000021666 Ensembl peptide - ENSMUSP00000152881 Ensembl peptide - ENSMUSP00000152694 Ensembl peptide - ENSMUSP00000152556 Ensembl peptide - ENSMUSP00000152519 NCBI entrez gene - 19300 See in Manteia. MGI - MGI:1349217 RefSeq - XM_006515617 RefSeq - XM_006515616 RefSeq - XM_006515613 RefSeq - NM_008992 RefSeq - XM_006515614 RefSeq - XM_006515615 RefSeq Peptide - NP_033018 swissprot - O89016 swissprot - A0A1Y7VMS0 swissprot - A0A1Y7VLL1 swissprot - A0A1Y7VM74 swissprot - A0A1Y7VMF7 Ensembl - ENSMUSG00000021240

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
Abcd3 / P55096 / ATP-binding cassette, sub-family D (ALD), member 3 / P28288* / ATP binding cassette subfamily D member 3*	ENSMUSG00000028127	27
Abcd2 / ATP-binding cassette, sub-family D (ALD), member 2 / Q9UBJ2* / ATP binding cassette subfamily D member 2*	ENSMUSG00000055782	26
Abcd1 / P48410 / ATP-binding cassette, sub-family D (ALD), member 1 / P33897* / ATP binding cassette subfamily D member 1*	ENSMUSG00000031378	26

Protein motifs (from Interpro)

Interpro ID	Name
IPR003439	ABC transporter-like
IPR003593	AAA+ ATPase domain
IPR011527	ABC transporter type 1, transmembrane domain
IPR017871	ABC transporter, conserved site
IPR027417	P-loop containing nucleoside triphosphate hydrolase
IPR036640	ABC transporter type 1, transmembrane domain superfamily

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0009235	cobalamin metabolic process	IEA
biological_process	GO:0055085	transmembrane transport	IEA
biological_process	GO:1990830	cellular response to leukemia inhibitory factor	IEP
cellular_component	GO:0005789	endoplasmic reticulum membrane	IDA
cellular_component	GO:0016020	membrane	IEA
cellular_component	GO:0016021	integral component of membrane	IEA
molecular_function	GO:0000166	nucleotide binding	IEA
molecular_function	GO:0005524	ATP binding	IEA
molecular_function	GO:0016887	ATPase activity	IEA
molecular_function	GO:0042626	ATPase activity, coupled to transmembrane movement of substances	IEA

Pathways (from Reactome)

Pathway description

Cobalamin (Cbl, vitamin B12) transport and metabolism

Phenotype (from MGI, Zfin or HPO)

ID	Phenotype	Definition	Genetic BG
MP:0001413	abnormal response to new environment	"altered investigative behavior from controls in reactions associated with placing an animal in a new location" [CFG:Center for Functional Genomics , Northwestern University]	Show Allelic Composition: Mysm1^{tm1a(KOMP)Wtsi}/Mysm1⁺ Genetic Background: Not Specified
MP:0005316	abnormal response to tactile stimuli	"anomalous reflex action normally induced by touch or pain" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Mysm1^{tm1a(KOMP)Wtsi}/Mysm1⁺ Genetic Background: Not Specified

Interacting proteins (from Reactome)

Interactor ID

Name

Interaction type

No match

0 s.

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		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr