ENSMUSG00000021597


Mus musculus

Features
Gene ID: ENSMUSG00000021597
  
Biological name :Slf1
  
Synonyms : Q8R3P9 / Slf1 / SMC5-SMC6 complex localization factor 1
  
Possible biological names infered from orthology : Q9BQI6
  
Species: Mus musculus
  
Chr. number: 13
Strand: -1
Band: C1
Gene start: 77043088
Gene end: 77135473
  
Corresponding Affymetrix probe sets: 10410743 (MoGene1.0st)   10410756 (MoGene1.0st)   1423577_at (Mouse Genome 430 2.0 Array)   1430047_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000118312
Ensembl peptide - ENSMUSP00000124543
Ensembl peptide - ENSMUSP00000124865
Ensembl peptide - ENSMUSP00000124946
Ensembl peptide - ENSMUSP00000123982
NCBI entrez gene - 105377     See in Manteia.
MGI - MGI:2145448
RefSeq - XM_017315353
RefSeq - XM_011244456
RefSeq - XM_011244457
RefSeq - XM_017315350
RefSeq - XM_017315351
RefSeq - XM_017315352
RefSeq - NM_134071
RefSeq - XM_006517035
RefSeq - XM_011244452
RefSeq - XM_011244453
RefSeq - XM_011244454
RefSeq - XM_011244455
RefSeq Peptide - NP_598832
swissprot - E0CX75
swissprot - A0A0M3HEQ6
swissprot - Q8C211
swissprot - Q8R3P9
Ensembl - ENSMUSG00000021597
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 slf1ENSDARG00000102118Danio rerio
 ENSGALG00000027932Gallus gallus
 SLF1ENSG00000133302Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Ankrd31 / ankyrin repeat domain 31 / Q8N7Z5*ENSMUSG0000010956115
Bcor / Q8CGN4 / BCL-6 corepressor / Q6W2J9*ENSMUSG0000004036314
A2AQH4 / Bcorl1 / BCL-6 corepressor-like protein 1 / Q5H9F3* / BCL6 corepressor like 1*ENSMUSG0000003695911
Bard1 / O70445 / BRCA1-associated RING domain protein 1 / Q99728* / BRCA1 associated RING domain 1*ENSMUSG0000002619610
Tonsl / tonsoku-like, DNA repair protein / Q96HA7*ENSMUSG0000005932310
E9Q4F7 / Ankrd11 / Ankyrin repeat domain-containing protein 11 / Q6UB99* / ankyrin repeat domain 11*ENSMUSG000000355699
Ankrd12 / ankyrin repeat domain 12 / Q6UB98*ENSMUSG000000346478


Protein motifs (from Interpro)
Interpro ID Name
 IPR001357  BRCT domain
 IPR002110  Ankyrin repeat
 IPR020683  Ankyrin repeat-containing domain
 IPR036420  BRCT domain superfamily
 IPR036770  Ankyrin repeat-containing domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006281 DNA repair IEA
 biological_processGO:0006974 cellular response to DNA damage stimulus ISO
 biological_processGO:0031334 positive regulation of protein complex assembly IEA
 biological_processGO:0034184 positive regulation of maintenance of mitotic sister chromatid cohesion IEA
 biological_processGO:1990166 protein localization to site of double-strand break IEA
 biological_processGO:2000781 positive regulation of double-strand break repair IEA
 cellular_componentGO:0000786 nucleosome IDA
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005813 centrosome IDA
 cellular_componentGO:0005815 microtubule organizing center IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0035861 site of double-strand break IEA
 cellular_componentGO:0042405 nuclear inclusion body IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0031625 ubiquitin protein ligase binding IEA
 molecular_functionGO:0044877 protein-containing complex binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Axin1Fu-Tg1/Axin1tm1(Axin2)Cos
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J * CBA/J * FVB/N

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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