ENSMUSG00000021884


Mus musculus

Features
Gene ID: ENSMUSG00000021884
  
Biological name :Hacl1
  
Synonyms : 2-hydroxyacyl-CoA lyase 1 / Hacl1 / Q9QXE0
  
Possible biological names infered from orthology : Q9UJ83
  
Species: Mus musculus
  
Chr. number: 14
Strand: -1
Band: B
Gene start: 31598730
Gene end: 31641286
  
Corresponding Affymetrix probe sets: 10418747 (MoGene1.0st)   1449047_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000114922
Ensembl peptide - ENSMUSP00000154592
Ensembl peptide - ENSMUSP00000132913
Ensembl peptide - ENSMUSP00000130268
Ensembl peptide - ENSMUSP00000129090
Ensembl peptide - ENSMUSP00000120452
Ensembl peptide - ENSMUSP00000022437
Ensembl peptide - ENSMUSP00000114879
NCBI entrez gene - 56794     See in Manteia.
MGI - MGI:1929657
RefSeq - NM_019975
RefSeq Peptide - NP_064359
swissprot - D6RDE9
swissprot - D3YZ54
swissprot - E9Q7H7
swissprot - Q9QXE0
swissprot - E9Q0K0
swissprot - E9PWM4
Ensembl - ENSMUSG00000021884
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 hacl1ENSDARG00000020529Danio rerio
 HACL1ENSGALG00000011211Gallus gallus
 HACL1ENSG00000131373Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Ilvbl / Q8BU33 / Mus musculus ilvB (bacterial acetolactate synthase)-like (Ilvbl), transcript variant 4, mRNA. / A1L0T0* / ilvB acetolactate synthase like*ENSMUSG0000003276326
Hacl1 / Q9UJ83* / 2-hydroxyacyl-CoA lyase 1*ENSMUSG0000011502223


Protein motifs (from Interpro)
Interpro ID Name
 IPR011766  Thiamine pyrophosphate enzyme, C-terminal TPP-binding
 IPR012000  Thiamine pyrophosphate enzyme, central domain
 IPR012001  Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain
 IPR029035  DHS-like NAD/FAD-binding domain superfamily
 IPR029061  Thiamin diphosphate-binding fold


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001561 fatty acid alpha-oxidation ISS
 biological_processGO:0006629 lipid metabolic process IDA
 biological_processGO:0006631 fatty acid metabolic process IEA
 biological_processGO:0051259 protein complex oligomerization ISO
 cellular_componentGO:0005777 peroxisome ISS
 molecular_functionGO:0000287 magnesium ion binding IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0005102 signaling receptor binding ISO
 molecular_functionGO:0016829 lyase activity IDA
 molecular_functionGO:0016830 carbon-carbon lyase activity ISS
 molecular_functionGO:0030976 thiamine pyrophosphate binding IEA
 molecular_functionGO:0042802 identical protein binding ISO
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0048037 cofactor binding ISO


Pathways (from Reactome)
Pathway description
Alpha-oxidation of phytanate
Peroxisomal protein import


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000021884 Hacl1 / Q9QXE0 / 2-hydroxyacyl-CoA lyase 1 / Q9UJ83*  / complex






 

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