ENSMUSG00000021950


Mus musculus

Features
Gene ID: ENSMUSG00000021950
  
Biological name :Anxa8
  
Synonyms : Annexin A8 / Anxa8 / O35640
  
Possible biological names infered from orthology : annexin A8 like 1 / ANXA8L1 / P13928 / Q5VT79
  
Species: Mus musculus
  
Chr. number: 14
Strand: 1
Band: B
Gene start: 34085981
Gene end: 34100571
  
Corresponding Affymetrix probe sets: 10414065 (MoGene1.0st)   1417732_at (Mouse Genome 430 2.0 Array)   1425789_s_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000022519
Ensembl peptide - ENSMUSP00000113662
NCBI entrez gene - 11752     See in Manteia.
MGI - MGI:1201374
RefSeq - NM_013473
RefSeq - NM_001281845
RefSeq Peptide - NP_001268774
RefSeq Peptide - NP_038501
swissprot - O35640
swissprot - Q921D0
Ensembl - ENSMUSG00000021950
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000005956Gallus gallus
 ANXA8ENSG00000265190Homo sapiens
 Q5VT79ENSG00000264230Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Anxa5 / P48036 / Annexin A5 / P08758*ENSMUSG0000002771254
Anxa4 / P97429 / Mus musculus annexin A4 (Anxa4), transcript variant 1, mRNA. / P09525* / annexin A4*ENSMUSG0000002999453
Anxa6 / P14824 / Annexin A6 / P08133*ENSMUSG0000001834051
Anxa11 / P97384 / Annexin A11 / P50995*ENSMUSG0000002186651
Anxa7 / Q07076 / Annexin A7 / P20073*ENSMUSG0000002181448
Anxa3 / O35639 / Annexin A3 / P12429*ENSMUSG0000002948445
Anxa2 / P07356 / Annexin A2 / P07355*ENSMUSG0000003223144
Anxa1 / P10107 / Annexin A1 / P04083*ENSMUSG0000002465942


Protein motifs (from Interpro)
Interpro ID Name
 IPR001464  Annexin
 IPR009115  Annexin A8
 IPR018252  Annexin repeat, conserved site
 IPR018502  Annexin repeat
 IPR037104  Annexin superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007596 blood coagulation IEA
 biological_processGO:0007599 hemostasis IEA
 cellular_componentGO:0005829 cytosol ISO
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0031902 late endosome membrane ISO
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0005544 calcium-dependent phospholipid binding IEA
 molecular_functionGO:0005546 phosphatidylinositol-4,5-bisphosphate binding ISO
 molecular_functionGO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding ISO
 molecular_functionGO:0043325 phosphatidylinositol-3,4-bisphosphate binding ISO
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0051015 actin filament binding ISO


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0020332 impaired leukocyte tethering or rolling "reduced ability or inability in the transient adhesive interactions between leukocytes and endothelial cells lining blood vessels mediated primarily by selectins and which are typically the first step in cellular extravasation" [GO:0050901, ORCID: orcid.org/0000-0003-4606-0597]
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Allelic Composition: Irs2tm2Mfw/Irs2tm2Mfw,Tg(Nes-cre)1Kln/?
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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