ENSMUSG00000022557


Mus musculus

Features
Gene ID: ENSMUSG00000022557
  
Biological name :Bop1
  
Synonyms : Bop1 / P97452 / Ribosome biosis protein BOP1
  
Possible biological names infered from orthology : block of proliferation 1 / Q14137
  
Species: Mus musculus
  
Chr. number: 15
Strand: -1
Band: D3
Gene start: 76452989
Gene end: 76477277
  
Corresponding Affymetrix probe sets: 10429908 (MoGene1.0st)   1423264_at (Mouse Genome 430 2.0 Array)   1430491_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000023217
NCBI entrez gene - 12181     See in Manteia.
MGI - MGI:1334460
RefSeq - NM_013481
RefSeq Peptide - NP_038509
swissprot - P97452
Ensembl - ENSMUSG00000022557
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 bop1ENSDARG00000063627Danio rerio
 BOP1ENSG00000261236Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001680  WD40 repeat
 IPR012953  BOP1, N-terminal domain
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR017986  WD40-repeat-containing domain
 IPR019775  WD40 repeat, conserved site
 IPR028598  WD repeat BOP1/Erb1
 IPR036322  WD40-repeat-containing domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000027 ribosomal large subunit assembly IEA
 biological_processGO:0000448 cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IMP
 biological_processGO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IEA
 biological_processGO:0006364 rRNA processing IMP
 biological_processGO:0008283 cell proliferation IMP
 biological_processGO:0042254 ribosome biogenesis IEA
 biological_processGO:0042273 ribosomal large subunit biogenesis IMP
 biological_processGO:0051726 regulation of cell cycle IEA
 biological_processGO:1901796 regulation of signal transduction by p53 class mediator IEA
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005730 nucleolus IEA
 cellular_componentGO:0030687 preribosome, large subunit precursor IBA
 cellular_componentGO:0070545 PeBoW complex IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0043021 ribonucleoprotein complex binding IDA


Pathways (from Reactome)
Pathway description
Major pathway of rRNA processing in the nucleolus and cytosol


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000020430 Pes1 / Q9EQ61 / Pescadillo homolog / O00541* / pescadillo ribosomal biogenesis factor 1*  / complex
 ENSMUSG00000026019 Wdr12 / Q9JJA4 / WD repeat domain 12 / Q9GZL7*  / complex






 

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