ENSMUSG00000022818


Mus musculus

Features
Gene ID: ENSMUSG00000022818
  
Biological name :Cyp2ab1
  
Synonyms : Cyp2ab1 / cytochrome P450, family 2, subfamily ab, polypeptide 1
  
Possible biological names infered from orthology :
  
Species: Mus musculus
  
Chr. number: 16
Strand: -1
Band: A3
Gene start: 20308387
Gene end: 20323065
  
Corresponding Affymetrix probe sets: 10438468 (MoGene1.0st)   
  
Cross references: Ensembl peptide - ENSMUSP00000023513
Ensembl peptide - ENSMUSP00000138133
NCBI entrez gene - 224044     See in Manteia.
MGI - MGI:3644957
RefSeq - XM_017316954
RefSeq - NM_183158
RefSeq - XM_017316952
RefSeq - XM_017316953
RefSeq Peptide - NP_898981
swissprot - E9PZ31
swissprot - S4R196
Ensembl - ENSMUSG00000022818
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cyp2aa1ENSDARG00000099003Danio rerio
 cyp2aa11ENSDARG00000102805Danio rerio
 cyp2aa11ENSDARG00000103456Danio rerio
 cyp2aa2ENSDARG00000104811Danio rerio
 cyp2aa3ENSDARG00000103347Danio rerio
 cyp2aa4ENSDARG00000098803Danio rerio
 cyp2aa7ENSDARG00000103766Danio rerio
 cyp2aa8ENSDARG00000104540Danio rerio
 cyp2aa9ENSDARG00000098890Danio rerio
 cyp2x10.2ENSDARG00000006501Danio rerio
 cyp2x10.2ENSDARG00000068283Danio rerio
 cyp2x12ENSDARG00000068290Danio rerio
 cyp2x12ENSDARG00000092091Danio rerio
 cyp2x6ENSDARG00000079653Danio rerio
 cyp2x7ENSDARG00000044002Danio rerio
 cyp2x8ENSDARG00000043997Danio rerio
 cyp2x9ENSDARG00000070775Danio rerio
 CYP2AB1ENSGALG00000008283Gallus gallus
 CYP2AB2ENSGALG00000008178Gallus gallus
 CYP2AB3ENSGALG00000045351Gallus gallus
 CYP2AB4ENSGALG00000008105Gallus gallus
 CYP2AB5ENSGALG00000045255Gallus gallus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Cyp2t4 / cytochrome P450, family 2, subfamily t, polypeptide 4ENSMUSG0000007878736
Cyp2s1 / Q9DBX6 / Cytochrome P450 2S1 / Q96SQ9* / cytochrome P450 family 2 subfamily S member 1*ENSMUSG0000004070336
Cyp2c67 / cytochrome P450, family 2, subfamily c, polypeptide 67ENSMUSG0000006262433
Cyp21a1 / P08686* / CYP21A2* / cytochrome P450 family 21 subfamily A member 2*ENSMUSG0000002436533
Cyp2c68 / cytochrome P450, family 2, subfamily c, polypeptide 68ENSMUSG0000007488233
Cyp1b1 / Q64429 / Cytochrome P450 1B1 / Q16678* / cytochrome P450 family 1 subfamily B member 1*ENSMUSG0000002408730
Cyp1a1 / P00184 / Cytochrome P450 1A1 / P04798* / cytochrome P450 family 1 subfamily A member 1*ENSMUSG0000003231528
Cyp1a2 / P00186 / Cytochrome P450 1A2 / P05177* / cytochrome P450 family 1 subfamily A member 2*ENSMUSG0000003231026
P27786 / Cyp17a1 / Steroid 17-alpha-hydroxylase/17,20 lyase / P05093* / cytochrome P450 family 17 subfamily A member 1*ENSMUSG0000000355525


Protein motifs (from Interpro)
Interpro ID Name
 IPR001128  Cytochrome P450
 IPR002401  Cytochrome P450, E-class, group I
 IPR017972  Cytochrome P450, conserved site
 IPR036396  Cytochrome P450 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0055114 oxidation-reduction process IEA
 molecular_functionGO:0004497 monooxygenase activity IEA
 molecular_functionGO:0005506 iron ion binding IEA
 molecular_functionGO:0008395 steroid hydroxylase activity IBA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA
 molecular_functionGO:0020037 heme binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000689 abnormal spleen morphology "atypical structure of the organ that functions to filter blood and to store red corpuscles and platelets" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:27463]
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Allelic Composition: Coq6tm1b(EUCOMM)Hmgu/Coq6+
Genetic Background: C57BL/6N-Coq6tm1b(EUCOMM)Hmgu/J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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