ENSMUSG00000040703


Mus musculus

Features
Gene ID: ENSMUSG00000040703
  
Biological name :Cyp2s1
  
Synonyms : Cyp2s1 / Cytochrome P450 2S1 / Q9DBX6
  
Possible biological names infered from orthology : cytochrome P450 family 2 subfamily S member 1 / Q96SQ9
  
Species: Mus musculus
  
Chr. number: 7
Strand: -1
Band: A3
Gene start: 25802475
Gene end: 25816913
  
Corresponding Affymetrix probe sets: 10561128 (MoGene1.0st)   1428283_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000041175
Ensembl peptide - ENSMUSP00000122264
Ensembl peptide - ENSMUSP00000104032
NCBI entrez gene - 74134     See in Manteia.
MGI - MGI:1921384
RefSeq - NM_028775
RefSeq Peptide - NP_083051
swissprot - D3Z7F1
swissprot - D3Z762
swissprot - Q9DBX6
Ensembl - ENSMUSG00000040703
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CYP2S1ENSG00000167600Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Cyp2t4 / cytochrome P450, family 2, subfamily t, polypeptide 4ENSMUSG0000007878745
Cyp2c67 / cytochrome P450, family 2, subfamily c, polypeptide 67ENSMUSG0000006262440
Cyp2c68 / cytochrome P450, family 2, subfamily c, polypeptide 68ENSMUSG0000007488240
Cyp1b1 / Q64429 / Cytochrome P450 1B1 / Q16678* / cytochrome P450 family 1 subfamily B member 1*ENSMUSG0000002408729
Cyp1a1 / P00184 / Cytochrome P450 1A1 / P04798* / cytochrome P450 family 1 subfamily A member 1*ENSMUSG0000003231528
Cyp21a1 / P08686* / CYP21A2* / cytochrome P450 family 21 subfamily A member 2*ENSMUSG0000002436527
Cyp1a2 / P00186 / Cytochrome P450 1A2 / P05177* / cytochrome P450 family 1 subfamily A member 2*ENSMUSG0000003231027
P27786 / Cyp17a1 / Steroid 17-alpha-hydroxylase/17,20 lyase / P05093* / cytochrome P450 family 17 subfamily A member 1*ENSMUSG0000000355524
Cyp2ab1 / cytochrome P450, family 2, subfamily ab, polypeptide 1ENSMUSG0000002281820


Protein motifs (from Interpro)
Interpro ID Name
 IPR001128  Cytochrome P450
 IPR002401  Cytochrome P450, E-class, group I
 IPR008067  Cytochrome P450, E-class, group I, CYP2A-like
 IPR036396  Cytochrome P450 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0019373 epoxygenase P450 pathway IBA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005783 endoplasmic reticulum ISO
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031090 organelle membrane IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 molecular_functionGO:0004497 monooxygenase activity IEA
 molecular_functionGO:0005506 iron ion binding IEA
 molecular_functionGO:0008392 arachidonic acid epoxygenase activity IBA
 molecular_functionGO:0008395 steroid hydroxylase activity IBA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen IEA
 molecular_functionGO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen IEA
 molecular_functionGO:0020037 heme binding IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0070330 aromatase activity IEA


Pathways (from Reactome)
Pathway description
Miscellaneous substrates
Xenobiotics
CYP2E1 reactions


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Robo2tm1Rilm/Robo2tm1Rilm,Olfr160tm4Mom/?,Omptm1(cre)Jae/Omp+
Genetic Background: involves: 129 * 129P2/OlaHsd * 129S1/Sv

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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