ENSMUSG00000022863


Mus musculus

Features
Gene ID: ENSMUSG00000022863
  
Biological name :Btg3
  
Synonyms : Btg3 / P50615 / Protein BTG3
  
Possible biological names infered from orthology : BTG anti-proliferation factor 3 / Q14201
  
Species: Mus musculus
  
Chr. number: 16
Strand: -1
Band: C3.1
Gene start: 78359860
Gene end: 78377192
  
Corresponding Affymetrix probe sets: 10440419 (MoGene1.0st)   10445875 (MoGene1.0st)   1449007_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000023570
Ensembl peptide - ENSMUSP00000119706
NCBI entrez gene - 12228     See in Manteia.
MGI - MGI:109532
RefSeq - NM_001297747
RefSeq - NM_009770
RefSeq Peptide - NP_001284676
RefSeq Peptide - NP_033900
swissprot - Q52L83
swissprot - P50615
swissprot - D3Z1M9
Ensembl - ENSMUSG00000022863
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 btg3ENSDARG00000069065Danio rerio
 BTG3ENSG00000154640Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Gm7334 / P50615 / predicted gene 7334 / BTG3* / Q14201* / BTG anti-proliferation factor 3*ENSMUSG00000044645100
Btg4 / O70552 / Protein BTG4 / Q9NY30* / BTG anti-proliferation factor 4*ENSMUSG0000003205641
Tob1 / Q61471 / Protein Tob1 / P50616* / transducer of ERBB2, 1*ENSMUSG0000003757325
Tob2 / Q9JM55 / transducer of ERBB2, 2 / Q14106*ENSMUSG0000004854623
Btg1 / P62325 / Protein BTG1 / P62324* / BTG anti-proliferation factor 1*ENSMUSG0000003647822
Btg1-ps1 / B cell translocation gene 1, anti-proliferative, pseudogene 1ENSMUSG0000006817321
Btg1-ps2 / B cell translocation gene 1, anti-proliferative, pseudogene 2ENSMUSG0000009834820
Btg2 / Q04211 / Protein BTG2 / P78543* / BTG anti-proliferation factor 2*ENSMUSG0000002042320


Protein motifs (from Interpro)
Interpro ID Name
 IPR002087  Anti-proliferative protein
 IPR036054  BTG-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0045930 negative regulation of mitotic cell cycle ISO
 cellular_componentGO:0005737 cytoplasm ISO
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002048 lung adenoma "benign epithelial neoplasm of the lung" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:57631]
Show

Allelic Composition: Nxf1Mvb1/Nxf1Mvb1,Usp14ax-J/Usp14ax-J
Genetic Background: involves: C57BL/6

 MP:0008014 lung tumor "presence of abnormal, rapidly proliferating cells on the lung usually in the form of a distinct mass" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Nxf1Mvb1/Nxf1Mvb1,Usp14ax-J/Usp14ax-J
Genetic Background: involves: C57BL/6

 MP:0008714 lung carcinoma "a malignant neoplasm of the ling, arising from epithelial cells, usually glandular or squamous" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Nxf1Mvb1/Nxf1Mvb1,Usp14ax-J/Usp14ax-J
Genetic Background: involves: C57BL/6

 MP:0014167 ectopic bone "the appearance of an extra bone structure at an atypical location" [MGI:csmith]
Show

Allelic Composition: Nxf1Mvb1/Nxf1Mvb1,Usp14ax-J/Usp14ax-J
Genetic Background: involves: C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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