ENSMUSG00000036478


Mus musculus

Features
Gene ID: ENSMUSG00000036478
  
Biological name :Btg1
  
Synonyms : Btg1 / P62325 / Protein BTG1
  
Possible biological names infered from orthology : BTG anti-proliferation factor 1 / P62324
  
Species: Mus musculus
  
Chr. number: 10
Strand: 1
Band: C3
Gene start: 96617006
Gene end: 96622809
  
Corresponding Affymetrix probe sets: 10365971 (MoGene1.0st)   1426083_a_at (Mouse Genome 430 2.0 Array)   1437455_a_at (Mouse Genome 430 2.0 Array)   1442018_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000151604
Ensembl peptide - ENSMUSP00000038863
NCBI entrez gene - 12226     See in Manteia.
MGI - MGI:88215
RefSeq - NM_007569
RefSeq Peptide - NP_031595
swissprot - A0A1W2P7F9
swissprot - P62325
swissprot - Q3UEG0
Ensembl - ENSMUSG00000036478
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 btg1ENSDARG00000027249Danio rerio
 BTG1ENSGALG00000011276Gallus gallus
 BTG1ENSG00000133639Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Btg1-ps1 / B cell translocation gene 1, anti-proliferative, pseudogene 1ENSMUSG0000006817380
Btg1-ps2 / B cell translocation gene 1, anti-proliferative, pseudogene 2ENSMUSG0000009834878
Btg2 / Q04211 / Protein BTG2 / P78543* / BTG anti-proliferation factor 2*ENSMUSG0000002042360
Tob1 / Q61471 / Protein Tob1 / P50616* / transducer of ERBB2, 1*ENSMUSG0000003757340
Tob2 / Q9JM55 / transducer of ERBB2, 2 / Q14106*ENSMUSG0000004854637
Gm7334 / P50615 / predicted gene 7334 / BTG3* / Q14201* / BTG anti-proliferation factor 3*ENSMUSG0000004464532
Btg3 / P50615 / Protein BTG3 / Q14201* / BTG anti-proliferation factor 3*ENSMUSG0000002286332
Btg4 / O70552 / Protein BTG4 / Q9NY30* / BTG anti-proliferation factor 4*ENSMUSG0000003205630


Protein motifs (from Interpro)
Interpro ID Name
 IPR002087  Anti-proliferative protein
 IPR033330  Protein BTG1
 IPR036054  BTG-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006479 protein methylation IDA
 biological_processGO:0006979 response to oxidative stress IEA
 biological_processGO:0007283 spermatogenesis IEA
 biological_processGO:0008285 negative regulation of cell proliferation IEA
 biological_processGO:0043085 positive regulation of catalytic activity NAS
 biological_processGO:0043434 response to peptide hormone IEA
 biological_processGO:0045603 positive regulation of endothelial cell differentiation IEA
 biological_processGO:0045663 positive regulation of myoblast differentiation IEA
 biological_processGO:0045766 positive regulation of angiogenesis IEA
 biological_processGO:2000271 positive regulation of fibroblast apoptotic process IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0019899 enzyme binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000812 abnormal dentate gyrus morphology "absence or malformation of one of two interlocking gyri of the hippocampus that contains granule cells, which project to the pyramidal cells and interneurons of the CA3 region of the ammon gyrus" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:cls, J:38857]
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Allelic Composition: Shh+/Shhtm1Chg,Zic2Ku/Zic2+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * BALB/cAnNCrl * C3H/HeH

 MP:0001469 abnormal contextual conditioning "defect in the ability of an animal to learn and remember an association between an an aversive experience (the unconditioned stimulus (US), ususally a shock) and a neutral stimulus (the conditioned stimulus (CS), or the environmental context in this case)" [CFG:Center for Functional Genomics , Northwestern University]
Show

Allelic Composition: Shh+/Shhtm1Chg,Zic2Ku/Zic2+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * BALB/cAnNCrl * C3H/HeH

 MP:0003203 increased neuron apoptosis "increase in the number of neurons undergoing programmed cell death" [RGD:Rat Genome Database submission]
Show

Allelic Composition: Shh+/Shhtm1Chg,Zic2Ku/Zic2+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * BALB/cAnNCrl * C3H/HeH

 MP:0012307 impaired spatial learning "impaired ability to ascertain or acquire spatial location information in order to improve navigation or other behavior using such location cues" [MGI:csmith]
Show

Allelic Composition: Shh+/Shhtm1Chg,Zic2Ku/Zic2+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * BALB/cAnNCrl * C3H/HeH

 MP:0020394 decreased neuronal precursor proliferation "reduction in the ability of a neuroblast population to undergo rapid expansion by cell division" [MGI:anna]
Show

Allelic Composition: Shh+/Shhtm1Chg,Zic2Ku/Zic2+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * BALB/cAnNCrl * C3H/HeH

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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