ENSMUSG00000024091


Mus musculus

Features
Gene ID: ENSMUSG00000024091
  
Biological name :Vapa
  
Synonyms : Q9WV55 / Vapa / vesicle-associated membrane protein, associated protein A
  
Possible biological names infered from orthology : Q9P0L0 / VAMP associated protein A
  
Species: Mus musculus
  
Chr. number: 17
Strand: -1
Band: E1.1
Gene start: 65580056
Gene end: 65613555
  
Corresponding Affymetrix probe sets: 10452470 (MoGene1.0st)   1416465_a_at (Mouse Genome 430 2.0 Array)   1416466_at (Mouse Genome 430 2.0 Array)   1448349_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000024897
NCBI entrez gene - 30960     See in Manteia.
MGI - MGI:1353561
RefSeq - XM_017317500
RefSeq - NM_013933
RefSeq - XM_006524385
RefSeq Peptide - NP_038961
swissprot - Q9WV55
Ensembl - ENSMUSG00000024091
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 top1mtENSDARG00000027824Danio rerio
 vapalENSDARG00000115862Danio rerio
 VAPAENSG00000101558Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Vapb / vesicle-associated membrane protein, associated protein B and C / O95292* / VAMP associated protein B and C*ENSMUSG0000005445559


Protein motifs (from Interpro)
Interpro ID Name
 IPR000535  Major sperm protein (MSP) domain
 IPR008962  PapD-like superfamily
 IPR013783  Immunoglobulin-like fold
 IPR016763  Vesicle-associated membrane-protein-associated protein
 IPR030229  Vesicle-associated membrane protein-associated protein A


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006888 ER to Golgi vesicle-mediated transport IEA
 biological_processGO:0008219 cell death IEA
 biological_processGO:0031175 neuron projection development IEA
 biological_processGO:0044791 positive regulation by host of viral release from host cell IEA
 biological_processGO:0044828 negative regulation by host of viral genome replication IEA
 biological_processGO:0044829 positive regulation by host of viral genome replication IEA
 biological_processGO:0070972 protein localization to endoplasmic reticulum ISS
 biological_processGO:0090114 COPII-coated vesicle budding IEA
 cellular_componentGO:0000139 Golgi membrane IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005783 endoplasmic reticulum ISO
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0005923 bicellular tight junction IEA
 cellular_componentGO:0015630 microtubule cytoskeleton IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0031965 nuclear membrane IEA
 cellular_componentGO:0031982 vesicle IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008017 microtubule binding IEA
 molecular_functionGO:0019904 protein domain specific binding IEA
 molecular_functionGO:0033149 FFAT motif binding ISO
 molecular_functionGO:0045296 cadherin binding IEA
 molecular_functionGO:0046982 protein heterodimerization activity IEA


Pathways (from Reactome)
Pathway description
Sphingolipid de novo biosynthesis
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000027784 Ppm1l / Q8BHN0 / Protein phosphatase 1L / Q5SGD2* / protein phosphatase, Mg2+/Mn2+ dependent 1L*  / complex
 ENSMUSG00000021669 Q9EQG9 / Col4a3bp / Collagen type IV alpha-3-binding protein / Q9Y5P4*  / reaction / complex






 

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