ENSMUSG00000024565


Mus musculus

Features
Gene ID: ENSMUSG00000024565
  
Biological name :Sall3
  
Synonyms : Q62255 / Sall3 / Sal-like protein 3
  
Possible biological names infered from orthology : Q9BXA9 / spalt like transcription factor 3
  
Species: Mus musculus
  
Chr. number: 18
Strand: -1
Band: E3
Gene start: 80966376
Gene end: 80986578
  
Corresponding Affymetrix probe sets: 10459999 (MoGene1.0st)   1441186_at (Mouse Genome 430 2.0 Array)   1452386_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000056967
NCBI entrez gene - 20689     See in Manteia.
MGI - MGI:109295
RefSeq - NM_178280
RefSeq - XM_006526459
RefSeq Peptide - NP_840064
swissprot - Q62255
Ensembl - ENSMUSG00000024565
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 sall3aENSDARG00000079613Danio rerio
 sall3bENSDARG00000057586Danio rerio
 SALL3ENSGALG00000041404Gallus gallus
 SALL3ENSG00000256463Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Sall1 / spalt like transcription factor 1 / Q9NSC2*ENSMUSG0000003166554
Sall4 / Q8BX22 / Sal-like protein 4 / Q9UJQ4* / spalt like transcription factor 4*ENSMUSG0000002754737
Sall2 / Q9QX96 / Sal-like protein 2 / Q9Y467* / spalt like transcription factor 2*ENSMUSG0000004953224


Protein motifs (from Interpro)
Interpro ID Name
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR013087  Zinc finger C2H2-type
 IPR036236  Zinc finger C2H2 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006366 transcription by RNA polymerase II IBA
 biological_processGO:0021891 olfactory bulb interneuron development IMP
 biological_processGO:0035136 forelimb morphogenesis IGI
 biological_processGO:0035137 hindlimb morphogenesis IGI
 biological_processGO:0045879 negative regulation of smoothened signaling pathway IGI
 cellular_componentGO:0005634 nucleus IBA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IBA
 molecular_functionGO:0043565 sequence-specific DNA binding IBA
 molecular_functionGO:0044212 transcription regulatory region DNA binding IBA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000746 weakness "state of being infirm or less strong than littermates" [J:45400]
Show

Allelic Composition: Tbk1tm1Aki/Tbk1tm1Aki
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0000762 abnormal tongue morphology "anomalous structure or development of the mobile mass of muscular tissue and surrounding epithelial tissue occupying the cavity of the mouth and forming part of the floor" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Tbk1tm1Aki/Tbk1tm1Aki
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0000959 abnormal somatic sensory system morphology 
Show

Allelic Composition: Tbk1tm1Aki/Tbk1tm1Aki
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0001056 abnormal cranial nerve morphology "any anomaly, deformity, or malformation of any of the twelve nerves that emerge from the cranium as opposed to the spinal nerves" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:cls, J:45302]
Show

Allelic Composition: Tbk1tm1Aki/Tbk1tm1Aki
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0001076 abnormal hypoglossal nerve morphology "malformation or misprojection of motor axons to the tongue" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:cls, J:45302]
Show

Allelic Composition: Tbk1tm1Aki/Tbk1tm1Aki
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0001429 dehydration "excessive water loss from the body or from an organ or bodily part" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:50053]
Show

Allelic Composition: Tbk1tm1Aki/Tbk1tm1Aki
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0001436 abnormal suckling behavior "reduced ability or inability to exert suction by the mouth, or atypical suckling pattern" [J:16461]
Show

Allelic Composition: Tbk1tm1Aki/Tbk1tm1Aki
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0001523 impaired righting response "reduced ability or greater amount of time needed to recover from supine position" [J:25565]
Show

Allelic Composition: Tbk1tm1Aki/Tbk1tm1Aki
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0003154 abnormal soft palate "abnormality in the musculomembranous fold that partly separates the mouth and pharynx, located behind the hard palate" [smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Tbk1tm1Aki/Tbk1tm1Aki
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0010371 abnormal epiglottis morphology "any structural anomaly of the most superior of the laryngeal cartilages, which is found at the root of the tongue and folds back over the entrance to the larynx during swallowing, preventing inhalation of food or drink" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Tbk1tm1Aki/Tbk1tm1Aki
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0011087 complete neonatal lethality "death of all organisms of a given genotype in a population within the neonatal period after birth (Mus: P0)" [MGI:csmith]
Show

Allelic Composition: Tbk1tm1Aki/Tbk1tm1Aki
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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