ENSMUSG00000024797


Mus musculus

Features
Gene ID: ENSMUSG00000024797
  
Biological name :Vps51
  
Synonyms : Q3UVL4 / Vps51 / VPS51 GARP complex subunit
  
Possible biological names infered from orthology : Q9UID3
  
Species: Mus musculus
  
Chr. number: 19
Strand: -1
Band: A
Gene start: 6067842
Gene end: 6080324
  
Corresponding Affymetrix probe sets: 10465354 (MoGene1.0st)   1429834_a_at (Mouse Genome 430 2.0 Array)   1438205_at (Mouse Genome 430 2.0 Array)   1454825_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000123857
Ensembl peptide - ENSMUSP00000123994
Ensembl peptide - ENSMUSP00000124244
Ensembl peptide - ENSMUSP00000124842
MGI - MGI:1915755
swissprot - Q3UVL4
swissprot - F6TKZ2
swissprot - E0CX85
Ensembl - ENSMUSG00000024797
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 vps51ENSDARG00000062016Danio rerio
 VPS51ENSGALG00000004166Gallus gallus
 VPS51ENSG00000149823Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q3UVL4 / Q71KT5 / Tm7sf2 / transmembrane 7 superfamily member 2 / VPS51* / Q9UID3* / VPS51, GARP complex subunit*ENSMUSG00000024799100


Protein motifs (from Interpro)
Interpro ID Name
 IPR014812  Vacuolar protein sorting-associated protein 51
 IPR016159  Cullin repeat-like-containing domain superfamily
 IPR035899  Dbl homology (DH) domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006869 lipid transport IEA
 biological_processGO:0006914 autophagy ISO
 biological_processGO:0007030 Golgi organization IBA
 biological_processGO:0007041 lysosomal transport ISO
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0032456 endocytic recycling IBA
 biological_processGO:0042147 retrograde transport, endosome to Golgi ISS
 biological_processGO:0048193 Golgi vesicle transport IBA
 cellular_componentGO:0000938 GARP complex ISO
 cellular_componentGO:0005730 nucleolus ISO
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005794 Golgi apparatus ISO
 cellular_componentGO:0005802 trans-Golgi network ISO
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0016020 membrane ISO
 cellular_componentGO:0016021 integral component of membrane IBA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle ISO
 cellular_componentGO:0055037 recycling endosome ISS
 cellular_componentGO:1990745 EARP complex ISO
 molecular_functionGO:0003674 molecular_function ND


Pathways (from Reactome)
Pathway description
Retrograde transport at the Trans-Golgi-Network


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0010052 increased grip strength "greater ability to grasp and hold objects, often measured as time spent hanging from an object or wire" [ISBN:0471316393 "Crawley, JN, What s Wrong with my Mouse: Behavioral Phenotyping of Transgenic and Knockout Mice"]
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Allelic Composition: Tcf7l2tm1a(EUCOMM)Wtsi/Tcf7l2+
Genetic Background: C57BL/6N-Tcf7l2tm1a(EUCOMM)Wtsi/Wtsi

 MP:0011100 complete preweaning lethality "death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
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Allelic Composition: Trip13tm1.1(KOMP)Vlcg/Trip13tm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Trip13tm1.1(KOMP)Vlcg/Ucd

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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