ENSMUSG00000025081


Mus musculus

Features
Gene ID: ENSMUSG00000025081
  
Biological name :Tdrd1
  
Synonyms : Q99MV1 / Tdrd1 / Tudor domain-containing protein 1
  
Possible biological names infered from orthology : Q9BXT4 / tudor domain containing 1
  
Species: Mus musculus
  
Chr. number: 19
Strand: 1
Band: D2
Gene start: 56826209
Gene end: 56870012
  
Corresponding Affymetrix probe sets: 10464171 (MoGene1.0st)   1421513_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000077785
Ensembl peptide - ENSMUSP00000107231
Ensembl peptide - ENSMUSP00000107233
Ensembl peptide - ENSMUSP00000112786
NCBI entrez gene - 83561     See in Manteia.
MGI - MGI:1933218
RefSeq - XM_006527479
RefSeq - NM_001002238
RefSeq - NM_001002240
RefSeq - NM_001002241
RefSeq - NM_031387
RefSeq - XM_006527474
RefSeq - XM_006527475
RefSeq - XM_006527476
RefSeq - XM_006527477
RefSeq - XM_006527478
RefSeq - XM_006527473
RefSeq Peptide - NP_001002240
RefSeq Peptide - NP_001002241
RefSeq Peptide - NP_113564
RefSeq Peptide - NP_001002238
swissprot - Q99MV1
Ensembl - ENSMUSG00000025081
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tdrd1ENSDARG00000007465Danio rerio
 TDRD1ENSGALG00000046180Gallus gallus
 TDRD1ENSG00000095627Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Rnf17 / Q99MV7 / RING finger protein 17 / Q9BXT8*ENSMUSG0000000036520
Tdrd6 / tudor domain-containing protein 6 isoform 3 / O60522* / tudor domain containing 6*ENSMUSG0000004014018
Tdrd5 / Q5VCS6 / Tudor domain-containing protein 5 / Q8NAT2* / tudor domain containing 5*ENSMUSG000000609859
Tdrkh / Q80VL1 / Mus musculus tudor and KH domain containing protein (Tdrkh), transcript variant 4, mRNA. / Q9Y2W6* / tudor and KH domain containing*ENSMUSG000000419127


Protein motifs (from Interpro)
Interpro ID Name
 IPR002893  Zinc finger, MYND-type
 IPR002999  Tudor domain
 IPR035437  SNase-like, OB-fold superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007281 germ cell development IMP
 biological_processGO:0007283 spermatogenesis IMP
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0031047 gene silencing by RNA IMP
 biological_processGO:0034587 piRNA metabolic process IMP
 biological_processGO:0043046 DNA methylation involved in gamete generation IMP
 biological_processGO:0051321 meiotic cell cycle IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0033391 chromatoid body IDA
 cellular_componentGO:0043186 P granule IDA
 cellular_componentGO:0071546 pi-body IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001125 abnormal oocytes "anomalous structure of immature ova" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Tyrc-Brd/Tyrc-Brd
Genetic Background: C57BL/6Brd-Tyrc-Brd

 MP:0001147 small testis "reduced size of the male reproductive glands" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:58959]
Show

Allelic Composition: Tyrc-Brd/Tyrc-Brd
Genetic Background: C57BL/6Brd-Tyrc-Brd

 MP:0001155 arrest of spermatogenesis "block of the process by which spermatogonial stem cells divide and differentiate into spermatozoa" [J:62271]
Show

Allelic Composition: Tyrc-Brd/Tyrc-Brd
Genetic Background: C57BL/6Brd-Tyrc-Brd

 MP:0001156 abnormal spermatogenesis "incomplete maturation or aberrant formation of the male gametes" [J:58959]
Show

Allelic Composition: Tyrc-Brd/Tyrc-Brd
Genetic Background: C57BL/6Brd-Tyrc-Brd

 MP:0001925 male infertility "inability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409]
Show

Allelic Composition: Tyrc-Brd/Tyrc-Brd
Genetic Background: C57BL/6Brd-Tyrc-Brd

 MP:0005159 azoospermia "absence of living spermatozoa " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Tyrc-Brd/Tyrc-Brd
Genetic Background: C57BL/6Brd-Tyrc-Brd

 MP:0006379 abnormal spermatocyte morphology "anomaly in the number or structure of male germ cells that through meiosis give rise to spermatids " [ISBN:0-8036-0655-99 "Taber s Cyclopedic Medical Dictionary, 19th edition", MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Tyrc-Brd/Tyrc-Brd
Genetic Background: C57BL/6Brd-Tyrc-Brd

 MP:0006380 abnormal spermatid morphology "anomaly in the number or structure of the male germ cells that without further cell division give rise to mature spermatozoa" [ISBN:0-8036-0655-99 "Taber s Cyclopedic Medical Dictionary, 19th edition", MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Tyrc-Brd/Tyrc-Brd
Genetic Background: C57BL/6Brd-Tyrc-Brd

 MP:0008280 male germ cell apoptosis "presence of male germs cells that undergo programmed cell death" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Tyrc-Brd/Tyrc-Brd
Genetic Background: C57BL/6Brd-Tyrc-Brd

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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