ENSMUSG00000025572


Mus musculus

Features
Gene ID: ENSMUSG00000025572
  
Biological name :Tmc6
  
Synonyms : Q7TN60 / Tmc6 / transmembrane channel-like gene family 6
  
Possible biological names infered from orthology : Q7Z403 / transmembrane channel like 6
  
Species: Mus musculus
  
Chr. number: 11
Strand: -1
Band: E2
Gene start: 117765988
Gene end: 117782198
  
Corresponding Affymetrix probe sets: 10393408 (MoGene1.0st)   1423770_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000099314
Ensembl peptide - ENSMUSP00000116521
Ensembl peptide - ENSMUSP00000123264
Ensembl peptide - ENSMUSP00000122495
Ensembl peptide - ENSMUSP00000118068
Ensembl peptide - ENSMUSP00000117566
Ensembl peptide - ENSMUSP00000116613
Ensembl peptide - ENSMUSP00000026659
NCBI entrez gene - 217353     See in Manteia.
MGI - MGI:1098686
RefSeq - XM_006533113
RefSeq - XM_006533115
RefSeq - XM_006533116
RefSeq - XM_006533117
RefSeq - XM_006533118
RefSeq - XM_006533119
RefSeq - XM_006533120
RefSeq - XM_006533122
RefSeq - NM_181321
RefSeq - XM_006533112
RefSeq - XM_006533114
RefSeq - NM_145439
RefSeq Peptide - NP_663414
RefSeq Peptide - NP_851838
swissprot - Q7TN60
swissprot - B1ATB7
swissprot - B1ATB6
swissprot - B1ATB5
swissprot - B1ATB3
swissprot - F7D254
swissprot - A0A0G2JDA0
swissprot - D6RCY1
Ensembl - ENSMUSG00000025572
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tmc6aENSDARG00000069787Danio rerio
 TMC6ENSGALG00000038875Gallus gallus
 TMC6ENSG00000141524Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Tmc5 / Q32NZ6 / Transmembrane channel-like protein 5 / Q6UXY8* / transmembrane channel like 5*ENSMUSG0000003065031
Tmc7 / Q8C428 / Transmembrane channel-like protein 7 / Q7Z402* / transmembrane channel like 7*ENSMUSG0000004224620
Tmc2 / Q8R4P4 / Transmembrane channel-like protein 2 / Q8TDI7* / transmembrane channel like 2*ENSMUSG0000006033219
Tmc8 / Q7TN58 / Transmembrane channel-like protein 8 / Q8IU68* / transmembrane channel like 8*ENSMUSG0000005010619
Tmc3 / transmembrane channel like 3 / Q7Z5M5*ENSMUSG0000003854019
Tmc4 / transmembrane channel like 4ENSMUSG0000001973418
Tmc1 / Q8R4P5 / Transmembrane channel-like protein 1 / Q8TDI8* / transmembrane channel like 1*ENSMUSG0000002474917


Protein motifs (from Interpro)
Interpro ID Name
 IPR012496  TMC domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0008150 biological_process ND
 cellular_componentGO:0005737 cytoplasm ISO
 cellular_componentGO:0005783 endoplasmic reticulum ISO
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0005794 Golgi apparatus ISO
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031965 nuclear membrane ISO
 molecular_functionGO:0003674 molecular_function ND


Pathways (from Reactome)
Pathway description
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001262 decreased body weight "lower than normal average weight " [J:61295]
Show

Allelic Composition: Syt1tm1a(EUCOMM)Wtsi/Syt1tm1a(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Syt1tm1a(EUCOMM)Wtsi/Wtsi

 MP:0002727 decreased circulating insulin level "less than normal levels of insulin in the blood" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, dlb:Donna Burkart , Mouse Genome Informatics Curator]
Show

Allelic Composition: Syt1tm1a(EUCOMM)Wtsi/Syt1tm1a(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Syt1tm1a(EUCOMM)Wtsi/Wtsi

 MP:0005632 decreased circulating aspartate transaminase level "less than normal concentration in the blood of this enzyme, which catalyzes the reversible transfer of an amine group from l-glutamic acid to oxaloacetic acid, forming alpha-ketoglutaric acid and l-aspartic acid; aids in diagnosis of viral hepatitis and myocardial infarction" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, RGD:Rat Genome Database submission]
Show

Allelic Composition: Syt1tm1a(EUCOMM)Wtsi/Syt1tm1a(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Syt1tm1a(EUCOMM)Wtsi/Wtsi

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

1 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr