ENSMUSG00000025816


Mus musculus

Features
Gene ID: ENSMUSG00000025816
  
Biological name :Sec61a2
  
Synonyms : Q9JLR1 / Sec61a2 / Sec61, alpha subunit 2 (S. cerevisiae)
  
Possible biological names infered from orthology : Q9H9S3 / Sec61 translocon alpha 2 subunit
  
Species: Mus musculus
  
Chr. number: 2
Strand: -1
Band: A1
Gene start: 5870987
Gene end: 5895432
  
Corresponding Affymetrix probe sets: 10479887 (MoGene1.0st)   1420644_a_at (Mouse Genome 430 2.0 Array)   1449944_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000141333
Ensembl peptide - ENSMUSP00000026926
Ensembl peptide - ENSMUSP00000100046
Ensembl peptide - ENSMUSP00000141220
NCBI entrez gene - 57743     See in Manteia.
MGI - MGI:1931071
RefSeq - XM_017319152
RefSeq - NM_001356411
RefSeq - NM_021305
RefSeq - XM_017319150
RefSeq - XM_017319151
RefSeq Peptide - NP_067280
RefSeq Peptide - NP_001343340
swissprot - Q9CYJ6
swissprot - A2ATT9
swissprot - Q9JLR1
swissprot - A0A0A6YVQ7
Ensembl - ENSMUSG00000025816
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 SEC61A2ENSGALG00000036300Gallus gallus
 Q9H9S3ENSG00000065665Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P61620 / Sec61a1 / Protein transport protein Sec61 subunit alpha isoform 1 / P61619* / Sec61 translocon alpha 1 subunit*ENSMUSG0000003008293


Protein motifs (from Interpro)
Interpro ID Name
 IPR002208  SecY/SEC61-alpha family
 IPR019561  Translocon Sec61/SecY, plug domain
 IPR023201  SecY domain superfamily
 IPR030659  SecY conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0015031 protein transport IEA
 cellular_componentGO:0005575 cellular_component ND
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0043022 ribosome binding IDA


Pathways (from Reactome)
Pathway description
XBP1(S) activates chaperone genes


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000027706 Sec62 / Q8BU14 / Translocation protein SEC62 / Q99442* / SEC62 homolog, preprotein translocation factor*  / complex
 ENSMUSG00000030082 P61620 / Sec61a1 / Protein transport protein Sec61 subunit alpha isoform 1 / P61619* / Sec61 translocon alpha 1 subunit*  / complex
 ENSMUSG00000019802 Sec63 / Q8VHE0 / Mus musculus SEC63-like (S. cerevisiae) (Sec63), transcript variant 2, mRNA. / Q9UGP8* / SEC63 homolog, protein translocation regulator*  / complex
 ENSMUSG00000053317 Q9CQS8 / Sec61b / Protein transport protein Sec61 subunit beta / P60468* / Sec61 translocon beta subunit*  / complex
 ENSMUSG00000052456 Asna1 / O54984 / ATPase Asna1 / O43681* / arsA arsenite transporter, ATP-binding, homolog 1 (bacterial)*  / reaction
 ENSMUSG00000078974 P60060 / Sec61g / Protein transport protein Sec61 subunit gamma / P60059* / Sec61 translocon gamma subunit*  / complex






 

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