ENSMUSG00000053317


Mus musculus

Features
Gene ID: ENSMUSG00000053317
  
Biological name :Sec61b
  
Synonyms : Protein transport protein Sec61 subunit beta / Q9CQS8 / Sec61b
  
Possible biological names infered from orthology : P60468 / Sec61 translocon beta subunit
  
Species: Mus musculus
  
Chr. number: 4
Strand: 1
Band: B1
Gene start: 47474658
Gene end: 47483242
  
Corresponding Affymetrix probe sets: 10411454 (MoGene1.0st)   10426889 (MoGene1.0st)   10504831 (MoGene1.0st)   1417083_at (Mouse Genome 430 2.0 Array)   1427862_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000067681
Ensembl peptide - ENSMUSP00000120880
Ensembl peptide - ENSMUSP00000114184
NCBI entrez gene - 66212     See in Manteia.
MGI - MGI:1913462
RefSeq - NM_024171
RefSeq Peptide - NP_077133
swissprot - A8Y5P9
swissprot - A8Y5P8
swissprot - Q9CQS8
Ensembl - ENSMUSG00000053317
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 sec61bENSDARG00000076568Danio rerio
 SEC61BENSGALG00000013569Gallus gallus
 P60468ENSG00000106803Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Gm10320 / P60468* / SEC61B* / Sec61 translocon beta subunit*ENSMUSG0000009211697


Protein motifs (from Interpro)
Interpro ID Name
 IPR016482  Protein transport protein SecG/Sec61-beta/Sbh
 IPR030671  Protein transport Sec61-beta/Sbh


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000060 protein import into nucleus, translocation ISO
 biological_processGO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation IBA
 biological_processGO:0006886 intracellular protein transport IEA
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0030433 ubiquitin-dependent ERAD pathway ISO
 biological_processGO:0030970 retrograde protein transport, ER to cytosol ISO
 biological_processGO:0031204 posttranslational protein targeting to membrane, translocation IBA
 biological_processGO:0065009 regulation of molecular function IEA
 cellular_componentGO:0005783 endoplasmic reticulum ISO
 cellular_componentGO:0005784 Sec61 translocon complex IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0016020 membrane ISO
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031205 endoplasmic reticulum Sec complex IBA
 cellular_componentGO:0044322 endoplasmic reticulum quality control compartment IDA
 molecular_functionGO:0005086 ARF guanyl-nucleotide exchange factor activity IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity IBA
 molecular_functionGO:0043022 ribosome binding IDA
 molecular_functionGO:0048408 epidermal growth factor binding ISO


Pathways (from Reactome)
Pathway description
XBP1(S) activates chaperone genes


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000025816 Q9JLR1 / Sec61a2 / Sec61, alpha subunit 2 (S. cerevisiae) / Q9H9S3* / Sec61 translocon alpha 2 subunit*  / complex
 ENSMUSG00000019802 Sec63 / Q8VHE0 / Mus musculus SEC63-like (S. cerevisiae) (Sec63), transcript variant 2, mRNA. / Q9UGP8* / SEC63 homolog, protein translocation regulator*  / complex
 ENSMUSG00000027706 Sec62 / Q8BU14 / Translocation protein SEC62 / Q99442* / SEC62 homolog, preprotein translocation factor*  / complex
 ENSMUSG00000030082 P61620 / Sec61a1 / Protein transport protein Sec61 subunit alpha isoform 1 / P61619* / Sec61 translocon alpha 1 subunit*  / complex
 ENSMUSG00000052456 Asna1 / O54984 / ATPase Asna1 / O43681* / arsA arsenite transporter, ATP-binding, homolog 1 (bacterial)*  / reaction
 ENSMUSG00000078974 P60060 / Sec61g / Protein transport protein Sec61 subunit gamma / P60059* / Sec61 translocon gamma subunit*  / complex






 

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