ENSMUSG00000025952


Mus musculus

Features
Gene ID: ENSMUSG00000025952
  
Biological name :Crygc
  
Synonyms : Crygc / Gamma-crystallin C / Q61597
  
Possible biological names infered from orthology : crystallin gamma C / P07315
  
Species: Mus musculus
  
Chr. number: 1
Strand: -1
Band: C2
Gene start: 65071525
Gene end: 65073689
  
Corresponding Affymetrix probe sets: 10355193 (MoGene1.0st)   1422674_s_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000027089
Ensembl peptide - ENSMUSP00000109698
NCBI entrez gene - 12966     See in Manteia.
MGI - MGI:88523
RefSeq - NM_007775
RefSeq - NM_001082573
RefSeq Peptide - NP_001076042
RefSeq Peptide - NP_031801
swissprot - Q61597
swissprot - A3RLD5
swissprot - A3RLD4
Ensembl - ENSMUSG00000025952
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CR391987.1ENSDARG00000069827Danio rerio
 crygm1ENSDARG00000016421Danio rerio
 crygm2bENSDARG00000115234Danio rerio
 crygm2cENSDARG00000117097Danio rerio
 crygm2d1ENSDARG00000087324Danio rerio
 crygm2d10ENSDARG00000087765Danio rerio
 crygm2d12ENSDARG00000069801Danio rerio
 crygm2d14ENSDARG00000087301Danio rerio
 crygm2d2ENSDARG00000086917Danio rerio
 crygm2d20ENSDARG00000091148Danio rerio
 crygm2d3ENSDARG00000088823Danio rerio
 crygm2d3ENSDARG00000087164Danio rerio
 crygm2d5ENSDARG00000069792Danio rerio
 crygm2d6ENSDARG00000073874Danio rerio
 crygm2d7ENSDARG00000076572Danio rerio
 crygm2d9ENSDARG00000073750Danio rerio
 crygm2d9ENSDARG00000115701Danio rerio
 crygm2eENSDARG00000044875Danio rerio
 crygm2fENSDARG00000078134Danio rerio
 crygm3ENSDARG00000078189Danio rerio
 crygm4ENSDARG00000008219Danio rerio
 crygm5ENSDARG00000041179Danio rerio
 crygm6ENSDARG00000040735Danio rerio
 crygm7ENSDARG00000040736Danio rerio
 crygmxENSDARG00000053862Danio rerio
 crygmxl1ENSDARG00000018797Danio rerio
 crygmxl2ENSDARG00000074001Danio rerio
 si:dkey-57a22.13ENSDARG00000092345Danio rerio
 si:dkey-57a22.14ENSDARG00000092764Danio rerio
 si:dkey-57a22.15ENSDARG00000093318Danio rerio
 zgc:153846ENSDARG00000040738Danio rerio
 CRYGCENSG00000163254Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Crygb / P04344 / Gamma-crystallin B / P07316* / crystallin gamma B*ENSMUSG0000007365881
Cryga / P04345 / Gamma-crystallin A / P11844* / crystallin gamma A*ENSMUSG0000004442980
Crygd / P04342 / Gamma-crystallin D / P07320* / crystallin gamma D*ENSMUSG0000006729975
Crygf / Q9CXV3 / Gamma-crystallin F / CRYGD* / P07320* / crystallin gamma D*ENSMUSG0000002594573
Cryge / Q03740 / Gamma-crystallin E / CRYGD* / P07320* / crystallin gamma D*ENSMUSG0000007087072
Crygs / O35486 / Beta-crystallin S / P22914* / crystallin gamma S*ENSMUSG0000003350151
Crygn / Q8VHL5 / Gamma-crystallin N / Q8WXF5* / crystallin gamma N*ENSMUSG0000003813542
Crybb1 / Q9WVJ5 / Beta-crystallin B1 Beta-crystallin B1B / P53674* / crystallin beta B1*ENSMUSG0000002934337
Crybb2 / P62696 / Beta-crystallin B2 / P43320* / crystallin beta B2*ENSMUSG0000004224037
Cryba2 / Q9JJV1 / Beta-crystallin A2 / P53672* / crystallin beta A2*ENSMUSG0000000654635
Crybb3 / Q9JJU9 / Mus musculus crystallin, beta B3 (Crybb3), transcript variant 8, mRNA. / P26998* / crystallin beta B3*ENSMUSG0000002935235
Cryba1 / beta-crystallin A1 isoform 2 / P05813* / crystallin beta A1*ENSMUSG0000000072432
Cryba4 / Q9JJV0 / Beta-crystallin A4 / P53673* / crystallin beta A4*ENSMUSG0000006697531


Protein motifs (from Interpro)
Interpro ID Name
 IPR001064  Beta/gamma crystallin
 IPR011024  Gamma-crystallin-like
 IPR033483  Gamma-crystallin C


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001654 eye development IMP
 biological_processGO:0007601 visual perception IEA
 biological_processGO:0043010 camera-type eye development IMP
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0005212 structural constituent of eye lens IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001297 microphthalmia "reduced average size of the eyes" [J:18048]
Show

Allelic Composition: CrygcChl3/CrygcChl3
Genetic Background: involves: 102/El * C3H/El

 MP:0001303 abnormal lens morphology "malformed transparent structure of the eye responsible for focusing light rays" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:40203]
Show

Allelic Composition: CrygdK10/Crygd+
Genetic Background: involves: 102/El * C3H * T STOCK

Allelic Composition: CrygcMNU8/Crygc+
Genetic Background: involves: 102/El * C3H * T STOCK

Allelic Composition: CrygcM1Sbao/CrygcM1Sbao
Genetic Background: involves: BALB/cJ * ICR

Allelic Composition: CrygcM1Sbao/Crygc+
Genetic Background: involves: BALB/cJ * ICR

 MP:0001304 cataracts "complete or partial opacity of the lens" [J:65031]
Show

Allelic Composition: Gjc1tm1Kni/Gjc1tm1Kni
Genetic Background: involves: 129S/SvEv * C57BL/6

Allelic Composition: CrygcChl3/CrygcChl3
Genetic Background: involves: 102/El * C3H/El

Allelic Composition: CrygcMNU8/CrygcMNU8
Genetic Background: involves: 102/El * C3H * T STOCK

Allelic Composition: CrygcMNU8/Crygc+
Genetic Background: involves: 102/El * C3H * T STOCK

Allelic Composition: CrygcM1Sbao/Crygc+
Genetic Background: involves: BALB/cJ * ICR

 MP:0001306 small lens "reduced size of the transparent structure of the eye responsible for focusing light rays" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:49840]
Show

Allelic Composition: CrygcM1Sbao/CrygcM1Sbao
Genetic Background: involves: BALB/cJ * ICR

Allelic Composition: CrygcM1Sbao/Crygc+
Genetic Background: involves: BALB/cJ * ICR

 MP:0002092 abnormal eye morphology "abnormal development of the eye tissues resulting in morphological abnormality or abnormal structure of the visual system" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Capn8tm2.1Hiso/Capn8tm2.1Hiso
Genetic Background: C57BL/6-Capn8tm2.1Hiso

 MP:0002840 abnormal lens fibers morphology "structural anomaly of the elongated cells of the crystalline lens of the eye" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: CrygcMNU8/CrygcMNU8
Genetic Background: involves: 102/El * C3H * T STOCK

Allelic Composition: CrygcMNU8/Crygc+
Genetic Background: involves: 102/El * C3H * T STOCK

 MP:0003237 abnormal lens epithelium morphology "malformation in the one or more of the layers of epithelial cells in the lens" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:93301]
Show

Allelic Composition: CrygcM1Sbao/CrygcM1Sbao
Genetic Background: involves: BALB/cJ * ICR

 MP:0005253 abnormal eye physiology "anomalous function and/or activity of the ocular system or any of its parts" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: CrygcM1Sbao/Crygc+
Genetic Background: involves: BALB/cJ * ICR

 MP:0010254 nuclear cataracts "a lens opacity located in the dense, central part of the lens" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", ISBN:978-0-8493-0864-2 "Smith R.S. et al (ed.) Systematic Evaluation of the Mouse Eye: Anatomy, Pathology, and Biomethods"]
Show

Allelic Composition: CrygcM1Sbao/CrygcM1Sbao
Genetic Background: involves: BALB/cJ * ICR

Allelic Composition: CrygcM1Sbao/Crygc+
Genetic Background: involves: BALB/cJ * ICR

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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