ENSMUSG00000067299


Mus musculus

Features
Gene ID: ENSMUSG00000067299
  
Biological name :Crygd
  
Synonyms : Crygd / Gamma-crystallin D / P04342
  
Possible biological names infered from orthology : crystallin gamma D / P07320
  
Species: Mus musculus
  
Chr. number: 1
Strand: -1
Band: C2
Gene start: 65061872
Gene end: 65063452
  
Corresponding Affymetrix probe sets: 10355191 (MoGene1.0st)   1419141_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000045327
Ensembl peptide - ENSMUSP00000122528
NCBI entrez gene - 12967     See in Manteia.
MGI - MGI:88524
RefSeq - NM_007776
RefSeq Peptide - NP_031802
swissprot - F7CUK9
swissprot - P04342
Ensembl - ENSMUSG00000067299
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CR391987.1ENSDARG00000069827Danio rerio
 crygm1ENSDARG00000016421Danio rerio
 crygm2bENSDARG00000115234Danio rerio
 crygm2cENSDARG00000117097Danio rerio
 crygm2d1ENSDARG00000087324Danio rerio
 crygm2d10ENSDARG00000087765Danio rerio
 crygm2d12ENSDARG00000069801Danio rerio
 crygm2d14ENSDARG00000087301Danio rerio
 crygm2d2ENSDARG00000086917Danio rerio
 crygm2d20ENSDARG00000091148Danio rerio
 crygm2d3ENSDARG00000088823Danio rerio
 crygm2d3ENSDARG00000087164Danio rerio
 crygm2d5ENSDARG00000069792Danio rerio
 crygm2d6ENSDARG00000073874Danio rerio
 crygm2d7ENSDARG00000076572Danio rerio
 crygm2d9ENSDARG00000073750Danio rerio
 crygm2d9ENSDARG00000115701Danio rerio
 crygm2eENSDARG00000044875Danio rerio
 crygm2fENSDARG00000078134Danio rerio
 crygm3ENSDARG00000078189Danio rerio
 crygm4ENSDARG00000008219Danio rerio
 crygm5ENSDARG00000041179Danio rerio
 crygm6ENSDARG00000040735Danio rerio
 crygm7ENSDARG00000040736Danio rerio
 crygmxENSDARG00000053862Danio rerio
 crygmxl1ENSDARG00000018797Danio rerio
 crygmxl2ENSDARG00000074001Danio rerio
 si:dkey-57a22.13ENSDARG00000092345Danio rerio
 si:dkey-57a22.14ENSDARG00000092764Danio rerio
 si:dkey-57a22.15ENSDARG00000093318Danio rerio
 zgc:153846ENSDARG00000040738Danio rerio
 CRYGDENSG00000118231Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Crygf / Q9CXV3 / Gamma-crystallin F / CRYGD* / P07320* / crystallin gamma D*ENSMUSG0000002594587
Cryge / Q03740 / Gamma-crystallin E / CRYGD* / P07320* / crystallin gamma D*ENSMUSG0000007087087
Crygb / P04344 / Gamma-crystallin B / P07316* / crystallin gamma B*ENSMUSG0000007365879
Cryga / P04345 / Gamma-crystallin A / P11844* / crystallin gamma A*ENSMUSG0000004442978
Crygc / Q61597 / Gamma-crystallin C / P07315* / crystallin gamma C*ENSMUSG0000002595275
Crygs / O35486 / Beta-crystallin S / P22914* / crystallin gamma S*ENSMUSG0000003350150
Crygn / Q8VHL5 / Gamma-crystallin N / Q8WXF5* / crystallin gamma N*ENSMUSG0000003813546
Crybb2 / P62696 / Beta-crystallin B2 / P43320* / crystallin beta B2*ENSMUSG0000004224037
Crybb1 / Q9WVJ5 / Beta-crystallin B1 Beta-crystallin B1B / P53674* / crystallin beta B1*ENSMUSG0000002934337
Crybb3 / Q9JJU9 / Mus musculus crystallin, beta B3 (Crybb3), transcript variant 8, mRNA. / P26998* / crystallin beta B3*ENSMUSG0000002935236
Cryba2 / Q9JJV1 / Beta-crystallin A2 / P53672* / crystallin beta A2*ENSMUSG0000000654636
Cryba1 / beta-crystallin A1 isoform 2 / P05813* / crystallin beta A1*ENSMUSG0000000072434
Cryba4 / Q9JJV0 / Beta-crystallin A4 / P53673* / crystallin beta A4*ENSMUSG0000006697533


Protein motifs (from Interpro)
Interpro ID Name
 IPR001064  Beta/gamma crystallin
 IPR011024  Gamma-crystallin-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001654 eye development IMP
 biological_processGO:0002088 lens development in camera-type eye IEA
 biological_processGO:0007601 visual perception ISO
 biological_processGO:0034614 cellular response to reactive oxygen species ISO
 biological_processGO:0043434 response to peptide hormone IEA
 biological_processGO:0070306 lens fiber cell differentiation IEA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005737 cytoplasm IDA
 molecular_functionGO:0005212 structural constituent of eye lens IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001303 abnormal lens morphology "malformed transparent structure of the eye responsible for focusing light rays" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:40203]
Show

Allelic Composition: CrygaTol/Cryga+
Genetic Background: involves: 102/El * C3H * T STOCK

Allelic Composition: CrygdK10/Crygd+
Genetic Background: involves: 102/El * C3H * T STOCK

Allelic Composition: CrygdENU4011/CrygdENU4011
Genetic Background: involves: 102/El * C3H * T STOCK

Allelic Composition: CrygdENU4011/Crygd+
Genetic Background: involves: 102/El * C3H * T STOCK

 MP:0001304 cataracts "complete or partial opacity of the lens" [J:65031]
Show

Allelic Composition: CrygbNop/Crygb+
Genetic Background: Not Specified

Allelic Composition: CrygdK10/CrygdK10
Genetic Background: involves: 102/El * C3H * T STOCK

Allelic Composition: CrygdK10/Crygd+
Genetic Background: involves: 102/El * C3H * T STOCK

Allelic Composition: CrygdENU4011/CrygdENU4011
Genetic Background: involves: 102/El * C3H * T STOCK

Allelic Composition: CrygdENU4011/Crygd+
Genetic Background: involves: 102/El * C3H * T STOCK

Allelic Composition: CrygdENU910/CrygdENU910
Genetic Background: involves: 102/El * C3H * T STOCK

Allelic Composition: CrygdENU910/Crygd+
Genetic Background: involves: 102/El * C3H * T STOCK

Allelic Composition: CrygdLop12/CrygdLop12
Genetic Background: involves: BALB/cJ * SJL/J

 MP:0001306 small lens "reduced size of the transparent structure of the eye responsible for focusing light rays" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:49840]
Show

Allelic Composition: CrygdK10/CrygdK10
Genetic Background: involves: 102/El * C3H * T STOCK

Allelic Composition: CrygdK10/Crygd+
Genetic Background: involves: 102/El * C3H * T STOCK

Allelic Composition: CrygdL23/CrygdL23
Genetic Background: involves: C57BL/6J

Allelic Composition: CrygdL23/Crygd+
Genetic Background: involves: C57BL/6J

 MP:0002840 abnormal lens fibers morphology "structural anomaly of the elongated cells of the crystalline lens of the eye" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: CrygdK10/CrygdK10
Genetic Background: involves: 102/El * C3H * T STOCK

Allelic Composition: CrygdK10/Crygd+
Genetic Background: involves: 102/El * C3H * T STOCK

Allelic Composition: CrygdENU4011/CrygdENU4011
Genetic Background: involves: 102/El * C3H * T STOCK

Allelic Composition: CrygdENU4011/Crygd+
Genetic Background: involves: 102/El * C3H * T STOCK

Allelic Composition: CrygdENU910/CrygdENU910
Genetic Background: involves: 102/El * C3H * T STOCK

Allelic Composition: CrygdENU910/Crygd+
Genetic Background: involves: 102/El * C3H * T STOCK

Allelic Composition: CrygdL23/CrygdL23
Genetic Background: involves: C57BL/6J

Allelic Composition: CrygdL23/Crygd+
Genetic Background: involves: C57BL/6J

 MP:0006225 ocular rupture "tearing of the tissues of the eye" [ncbi:Matthew Mailman, NCBI request, smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: CrygdL23/CrygdL23
Genetic Background: involves: C57BL/6J

 MP:0010254 nuclear cataracts "a lens opacity located in the dense, central part of the lens" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", ISBN:978-0-8493-0864-2 "Smith R.S. et al (ed.) Systematic Evaluation of the Mouse Eye: Anatomy, Pathology, and Biomethods"]
Show

Allelic Composition: KitlSl/KitlSl-d
Genetic Background: involves: C57BL/6 * WC

Allelic Composition: CrygdAey4/Crygd+
Genetic Background: C3HeB/FeJ-CrygdAey4

 MP:0010263 total cataracts "a lens opacity which involves both nuclear and cortical regions, including all fibers of a lens; usually congenital" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", ISBN:978-0-8493-0864-2 "Smith R.S. et al (ed.) Systematic Evaluation of the Mouse Eye: Anatomy, Pathology, and Biomethods"]
Show

Allelic Composition: CrygdL23/CrygdL23
Genetic Background: involves: C57BL/6J

Allelic Composition: CrygdL23/Crygd+
Genetic Background: involves: C57BL/6J

 MP:0011697 vacuolated lens "fluid filled cavities are present in the cytoplasm of the transparent structure of the eye responsible for focusing light" [MGI:llw2]
Show

Allelic Composition: CrygdK10/CrygdK10
Genetic Background: involves: 102/El * C3H * T STOCK

Allelic Composition: CrygdK10/Crygd+
Genetic Background: involves: 102/El * C3H * T STOCK

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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