ENSMUSG00000073658


Mus musculus

Features
Gene ID: ENSMUSG00000073658
  
Biological name :Crygb
  
Synonyms : Crygb / Gamma-crystallin B / P04344
  
Possible biological names infered from orthology : crystallin gamma B / P07316
  
Species: Mus musculus
  
Chr. number: 1
Strand: -1
Band: C2
Gene start: 65080219
Gene end: 65082288
  
Corresponding Affymetrix probe sets: 10355199 (MoGene1.0st)   1422674_s_at (Mouse Genome 430 2.0 Array)   1427264_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000027090
NCBI entrez gene - 12965     See in Manteia.
MGI - MGI:88522
RefSeq - NM_144761
RefSeq Peptide - NP_658906
swissprot - P04344
Ensembl - ENSMUSG00000073658
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CR391987.1ENSDARG00000069827Danio rerio
 crygm1ENSDARG00000016421Danio rerio
 crygm2bENSDARG00000115234Danio rerio
 crygm2cENSDARG00000117097Danio rerio
 crygm2d1ENSDARG00000087324Danio rerio
 crygm2d10ENSDARG00000087765Danio rerio
 crygm2d12ENSDARG00000069801Danio rerio
 crygm2d14ENSDARG00000087301Danio rerio
 crygm2d2ENSDARG00000086917Danio rerio
 crygm2d20ENSDARG00000091148Danio rerio
 crygm2d3ENSDARG00000088823Danio rerio
 crygm2d3ENSDARG00000087164Danio rerio
 crygm2d5ENSDARG00000069792Danio rerio
 crygm2d6ENSDARG00000073874Danio rerio
 crygm2d7ENSDARG00000076572Danio rerio
 crygm2d9ENSDARG00000073750Danio rerio
 crygm2d9ENSDARG00000115701Danio rerio
 crygm2eENSDARG00000044875Danio rerio
 crygm2fENSDARG00000078134Danio rerio
 crygm3ENSDARG00000078189Danio rerio
 crygm4ENSDARG00000008219Danio rerio
 crygm5ENSDARG00000041179Danio rerio
 crygm6ENSDARG00000040735Danio rerio
 crygm7ENSDARG00000040736Danio rerio
 crygmxENSDARG00000053862Danio rerio
 crygmxl1ENSDARG00000018797Danio rerio
 crygmxl2ENSDARG00000074001Danio rerio
 si:dkey-57a22.13ENSDARG00000092345Danio rerio
 si:dkey-57a22.14ENSDARG00000092764Danio rerio
 si:dkey-57a22.15ENSDARG00000093318Danio rerio
 zgc:153846ENSDARG00000040738Danio rerio
 CRYGBENSG00000182187Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Crygc / Q61597 / Gamma-crystallin C / P07315* / crystallin gamma C*ENSMUSG0000002595281
Crygf / Q9CXV3 / Gamma-crystallin F / CRYGD* / P07320* / crystallin gamma D*ENSMUSG0000002594580
Cryge / Q03740 / Gamma-crystallin E / CRYGD* / P07320* / crystallin gamma D*ENSMUSG0000007087079
Cryga / P04345 / Gamma-crystallin A / P11844* / crystallin gamma A*ENSMUSG0000004442978
Crygd / P04342 / Gamma-crystallin D / P07320* / crystallin gamma D*ENSMUSG0000006729978
Crygs / O35486 / Beta-crystallin S / P22914* / crystallin gamma S*ENSMUSG0000003350153
Crygn / Q8VHL5 / Gamma-crystallin N / Q8WXF5* / crystallin gamma N*ENSMUSG0000003813542
Crybb2 / P62696 / Beta-crystallin B2 / P43320* / crystallin beta B2*ENSMUSG0000004224038
Crybb3 / Q9JJU9 / Mus musculus crystallin, beta B3 (Crybb3), transcript variant 8, mRNA. / P26998* / crystallin beta B3*ENSMUSG0000002935237
Cryba2 / Q9JJV1 / Beta-crystallin A2 / P53672* / crystallin beta A2*ENSMUSG0000000654637
Cryba1 / beta-crystallin A1 isoform 2 / P05813* / crystallin beta A1*ENSMUSG0000000072436
Crybb1 / Q9WVJ5 / Beta-crystallin B1 Beta-crystallin B1B / P53674* / crystallin beta B1*ENSMUSG0000002934336
Cryba4 / Q9JJV0 / Beta-crystallin A4 / P53673* / crystallin beta A4*ENSMUSG0000006697533


Protein motifs (from Interpro)
Interpro ID Name
 IPR001064  Beta/gamma crystallin
 IPR011024  Gamma-crystallin-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001654 eye development IMP
 biological_processGO:0002088 lens development in camera-type eye IMP
 biological_processGO:0070307 lens fiber cell development IMP
 biological_processGO:0070309 lens fiber cell morphogenesis IMP
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005737 cytoplasm IDA
 molecular_functionGO:0005212 structural constituent of eye lens IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001303 abnormal lens morphology "malformed transparent structure of the eye responsible for focusing light rays" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:40203]
Show

Allelic Composition: H2b/H2b,Rag2tm1Fwa/Rag2tm1Fwa,Tg(TcraN15,TcrbN15)L2Elre/?
Genetic Background: involves: 129S/SvEv * C57BL/6

Allelic Composition: CrygbS11R/CrygbS11R
Genetic Background: A/J-CrygbS11R

Allelic Composition: CrygbS11R/CrygbS11R,Gja8tm1(Gja3)Tww/Gja8tm1(Gja3)Tww
Genetic Background: involves: A/J * C57BL/6J

 MP:0002840 abnormal lens fibers morphology "structural anomaly of the elongated cells of the crystalline lens of the eye" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: H2b/H2b,Rag2tm1Fwa/Rag2tm1Fwa,Tg(TcraN15,TcrbN15)L2Elre/?
Genetic Background: involves: 129S/SvEv * C57BL/6

Allelic Composition: CrygbS11R/CrygbS11R
Genetic Background: A/J-CrygbS11R

 MP:0010254 nuclear cataracts "a lens opacity located in the dense, central part of the lens" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", ISBN:978-0-8493-0864-2 "Smith R.S. et al (ed.) Systematic Evaluation of the Mouse Eye: Anatomy, Pathology, and Biomethods"]
Show

Allelic Composition: Cryba1Po1/Cryba1+
Genetic Background: C3HeB/FeJ-Cryba1Po1

Allelic Composition: CrygbNop/Crygb+
Genetic Background: Not Specified

Allelic Composition: CrygbS11R/Crygb+
Genetic Background: A/J-CrygbS11R

Allelic Composition: CrygbS11R/CrygbS11R
Genetic Background: A/J-CrygbS11R

 MP:0010262 lamellar cataracts "a concentric lens opacity which is limited to layers of the cortex, affecting one lamella or zonule of an otherwise clear lens; usually congenital" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", ISBN:978-0-8493-0864-2 "Smith R.S. et al (ed.) Systematic Evaluation of the Mouse Eye: Anatomy, Pathology, and Biomethods"]
Show

Allelic Composition: Pax3tm1Buck/Pax3tm1Buck,Pax7tm2Pgr/Pax7tm2Pgr
Genetic Background: either: (involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ) or (involves: 129P2/OlaHsd * 129S2/SvPas)

Allelic Composition: CrygbClapper/Crygb+
Genetic Background: C57BL/6J-CrygbClapper

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr