ENSMUSG00000026222


Mus musculus

Features
Gene ID: ENSMUSG00000026222
  
Biological name :Sp100
  
Synonyms : nuclear antigen Sp100 / O35892 / Sp100
  
Possible biological names infered from orthology : P23497 / Q9H930 / SP100 nuclear antigen / SP140L / SP140 nuclear body protein like
  
Species: Mus musculus
  
Chr. number: 1
Strand: 1
Band: C5
Gene start: 85649988
Gene end: 85709998
  
Corresponding Affymetrix probe sets: 10347948 (MoGene1.0st)   10347968 (MoGene1.0st)   10356262 (MoGene1.0st)   1434457_at (Mouse Genome 430 2.0 Array)   1451821_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000120267
Ensembl peptide - ENSMUSP00000119301
Ensembl peptide - ENSMUSP00000120604
Ensembl peptide - ENSMUSP00000122899
Ensembl peptide - ENSMUSP00000122670
Ensembl peptide - ENSMUSP00000051705
Ensembl peptide - ENSMUSP00000066399
Ensembl peptide - ENSMUSP00000116942
Ensembl peptide - ENSMUSP00000118481
NCBI entrez gene - 20684     See in Manteia.
MGI - MGI:109561
RefSeq - XM_017319443
RefSeq - NM_001313713
RefSeq - NM_001313714
RefSeq - NM_013673
RefSeq - XM_006529280
RefSeq - XM_006529281
RefSeq - XM_006529282
RefSeq - XM_006529283
RefSeq - XM_006529284
RefSeq - XM_006529285
RefSeq - XM_006529286
RefSeq - XM_006529288
RefSeq - XM_011247950
RefSeq - XM_017319442
RefSeq - NM_001313712
RefSeq Peptide - NP_001300641
RefSeq Peptide - NP_001300642
RefSeq Peptide - NP_001300643
RefSeq Peptide - NP_038701
swissprot - D6RIJ4
swissprot - O35892
swissprot - E9QA05
swissprot - Q8C405
swissprot - A0A1B0GX24
swissprot - Q6NTA3
swissprot - E9Q4Y0
swissprot - F6Q968
swissprot - F6WL90
Ensembl - ENSMUSG00000026222
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 sp100.1ENSDARG00000055359Danio rerio
 sp100.2ENSDARG00000102588Danio rerio
 sp100.3ENSDARG00000090449Danio rerio
 Q9H930ENSG00000185404Homo sapiens
 SP100ENSG00000067066Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Sp140 / Sp140 nuclear body protein / Q13342*ENSMUSG0000007003124
Sp110 / Q8BVK9 / Sp110 nuclear body protein / Q9HB58*ENSMUSG0000007003417
C130026I21Rik / RIKEN cDNA C130026I21 gene / SP140* / Q13342* / SP140 nuclear body protein*ENSMUSG0000005247711
A630001G21Rik / RIKEN cDNA A630001G21 geneENSMUSG0000005276010
A530032D15Rik / RIKEN cDNA A530032D15Rik gene / SP140* / Q13342* / SP140 nuclear body protein*ENSMUSG000000898449


Protein motifs (from Interpro)
Interpro ID Name
 IPR000770  SAND domain
 IPR001487  Bromodomain
 IPR004865  HSR domain
 IPR010919  SAND-like domain superfamily
 IPR011011  Zinc finger, FYVE/PHD-type
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR019787  Zinc finger, PHD-finger
 IPR036427  Bromodomain-like superfamily
 IPR037373  Transcription intermediary factor 1-beta


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000723 telomere maintenance ISS
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0010596 negative regulation of endothelial cell migration ISS
 biological_processGO:0045765 regulation of angiogenesis ISS
 biological_processGO:0046826 negative regulation of protein export from nucleus ISS
 biological_processGO:1902041 regulation of extrinsic apoptotic signaling pathway via death domain receptors ISS
 biological_processGO:1902044 regulation of Fas signaling pathway ISS
 biological_processGO:1903507 negative regulation of nucleic acid-templated transcription IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm ISS
 cellular_componentGO:0016605 PML body IEA
 cellular_componentGO:0030870 Mre11 complex ISS
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003714 transcription corepressor activity IEA
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
SUMOylation of DNA damage response and repair proteins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000015120 Ube2i / P63280 / ubiquitin-conjugating enzyme E2I / P63279*  / reaction
 ENSMUSG00000026021 Sumo1 / P63166 / Small ubiquitin-related modifier 1 / P63165* / small ubiquitin-like modifier 1*  / reaction / complex






 

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© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr