ENSMUSG00000026343


Mus musculus

Features
Gene ID: ENSMUSG00000026343
  
Biological name :Gpr39
  
Synonyms : Gpr39 / G protein-coupled receptor 39
  
Possible biological names infered from orthology : O43194
  
Species: Mus musculus
  
Chr. number: 1
Strand: 1
Band: E2.3
Gene start: 125676995
Gene end: 125873862
  
Corresponding Affymetrix probe sets: 10349401 (MoGene1.0st)   1432260_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000027581
NCBI entrez gene - 71111     See in Manteia.
MGI - MGI:1918361
RefSeq - NM_027677
RefSeq Peptide - NP_081953
swissprot - A0A0B4J1E4
Ensembl - ENSMUSG00000026343
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gpr39ENSDARG00000102888Danio rerio
 GPR39ENSGALG00000012171Gallus gallus
 GPR39ENSG00000183840Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Ntsr1 / O88319 / neurotensin receptor 1 / P30989*ENSMUSG0000002756824
Nmur2 / Q8BZ39 / Neuromedin-U receptor 2 / Q9GZQ4*ENSMUSG0000003739322
Ntsr2 / P70310 / Neurotensin receptor type 2 / O95665* / neurotensin receptor 2*ENSMUSG0000002059121
Nmur1 / O55040 / Neuromedin-U receptor 1 / Q9HB89*ENSMUSG0000002623721
Ghsr / Q99P50 / Growth hormone secretagogue receptor type 1 / Q92847* / growth hormone secretagogue receptor*ENSMUSG0000005113617
Trhr / P21761 / thyrotropin releasing hormone receptor / P34981*ENSMUSG0000003876017
Trhr2 / thyrotropin releasing hormone receptor 2ENSMUSG0000003907915


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR017452  GPCR, rhodopsin-like, 7TM


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA


Pathways (from Reactome)
Pathway description
Class A/1 (Rhodopsin-like receptors)
G alpha (q) signalling events
G alpha (s) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000503 excessive digestive secretion "increase in the production and/or release of a physiologically active substance (usually but not exclusively in liquid form) from a cell or a gland of the digestive system" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:tc]
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Allelic Composition: Ophn1tm1Bill/Y
Genetic Background: Not Specified

 MP:0001260 increased body weight "greater than normal average weight " [J:33400]
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Allelic Composition: Ophn1tm1Bill/Y
Genetic Background: Not Specified

 MP:0001664 abnormal digestion "altered ability of the mechanical, chemical, and enzymatic processes of the body to convert ingested food into material suitable for assimiliation for synthesis of tissues or liberation of energy " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Ophn1tm1Bill/Y
Genetic Background: Not Specified

 MP:0002727 decreased circulating insulin level "less than normal levels of insulin in the blood" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, dlb:Donna Burkart , Mouse Genome Informatics Curator]
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Allelic Composition: Gsk3btm1Jrw/Gsk3btm1Jrw
Genetic Background: involves: 129 * CD-1

 MP:0003883 enlarged stomach "increased size of the stomach" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator]
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Allelic Composition: Ophn1tm1Bill/Y
Genetic Background: Not Specified

 MP:0003961 decreased lean body mass "less than average fat-free physical bulk or volume of the body including all its components except adipose tissue" [honda:Hiraoki Onda, Mouse GEnome Informatics Curator]
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Allelic Composition: Ophn1tm1Bill/Y
Genetic Background: Not Specified

 MP:0005178 increased total circulating cholesterol level "greater than the normal concentration in the blood of these most abundant steroids in animal tissues, and precursors to steroid hormones and bile salts; also components of plasma membranes" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Ophn1tm1Bill/Y
Genetic Background: Not Specified

 MP:0005215 abnormal islet of Langerhans morphology "anomalous morphology of these structures that are scattered throughout the pancreas and comprise its endocrine portion; within each islet there are three cell types: alpha, beta, and delta " [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Gsk3btm1Jrw/Gsk3btm1Jrw
Genetic Background: involves: 129 * CD-1

 MP:0005458 increased percent body fat "more fat, relative to the norm, as a percentage of total body weight" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Ophn1tm1Bill/Y
Genetic Background: Not Specified

 MP:0005559 increased circulating glucose level "greater than the normal concentration in the blood of this major monosaccharide of the body; it is an important energy source" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, RGD:Rat Genome Database submission]
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Allelic Composition: Gsk3btm1Jrw/Gsk3btm1Jrw
Genetic Background: involves: 129 * CD-1

 MP:0006003 abnormal large intestinal transit time "increase or decrease in the time it takes for a bolus of material to pass through the large intestine" [smb:Susan M Bello, Mouse Genome Informatics Curator]
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Allelic Composition: Ophn1tm1Bill/Y
Genetic Background: Not Specified

 MP:0011082 abnormal gastrointestinal motility "anomaly in the propulsive movements of the digestive system, resulting in the transit of the contents along the gastrointestinal tract" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Ophn1tm1Bill/Y
Genetic Background: Not Specified

 MP:0011957 decreased compensatory feeding amount "decreased amount of food consumed after a period of fasting" [MGI:csmith]
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Allelic Composition: Ophn1tm1Bill/Y
Genetic Background: Not Specified

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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