ENSMUSG00000026429


Mus musculus

Features
Gene ID: ENSMUSG00000026429
  
Biological name :Ube2t
  
Synonyms : Q9CQ37 / Ube2t / ubiquitin-conjugating enzyme E2T
  
Possible biological names infered from orthology : Q9NPD8
  
Species: Mus musculus
  
Chr. number: 1
Strand: 1
Band: E4
Gene start: 134962565
Gene end: 134974162
  
Corresponding Affymetrix probe sets: 10350090 (MoGene1.0st)   1422462_at (Mouse Genome 430 2.0 Array)   1442398_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000139929
Ensembl peptide - ENSMUSP00000152910
Ensembl peptide - ENSMUSP00000027687
NCBI entrez gene - 67196     See in Manteia.
MGI - MGI:1914446
RefSeq - NM_026024
RefSeq - NM_001278115
RefSeq Peptide - NP_001265044
RefSeq Peptide - NP_080300
swissprot - Q9CQ37
swissprot - A0A286YCR4
swissprot - A0A087WPV1
Ensembl - ENSMUSG00000026429
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ube2tENSDARG00000063285Danio rerio
 UBE2TENSGALG00000000102Gallus gallus
 UBE2TENSG00000077152Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Ube2n / P61089 / ubiquitin-conjugating enzyme E2N / UBE2NL* / ubiquitin conjugating enzyme E2 N like (gene/pseudogene)*ENSMUSG0000007478133


Protein motifs (from Interpro)
Interpro ID Name
 IPR000608  Ubiquitin-conjugating enzyme E2
 IPR016135  Ubiquitin-conjugating enzyme/RWD-like
 IPR023313  Ubiquitin-conjugating enzyme, active site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000209 protein polyubiquitination IBA
 biological_processGO:0006281 DNA repair ISO
 biological_processGO:0006513 protein monoubiquitination IEA
 biological_processGO:0006974 cellular response to DNA damage stimulus IBA
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0035519 protein K29-linked ubiquitination IEA
 biological_processGO:0044314 protein K27-linked ubiquitination IEA
 biological_processGO:0051865 protein autoubiquitination IEA
 biological_processGO:0070534 protein K63-linked ubiquitination IEA
 biological_processGO:0070936 protein K48-linked ubiquitination IEA
 biological_processGO:0070979 protein K11-linked ubiquitination IEA
 biological_processGO:0085020 protein K6-linked ubiquitination IEA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005730 nucleolus IEA
 cellular_componentGO:0005737 cytoplasm IBA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003682 chromatin binding IEA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0031625 ubiquitin protein ligase binding IEA
 molecular_functionGO:0061630 ubiquitin protein ligase activity IBA
 molecular_functionGO:0061631 ubiquitin conjugating enzyme activity IEA


Pathways (from Reactome)
Pathway description
Fanconi Anemia Pathway
Synthesis of active ubiquitin: roles of E1 and E2 enzymes


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000025646 Atrip / Q8BMG1 / ATR-interacting protein / Q8WXE1*  / complex / reaction
 ENSMUSG00000012483 Rpa3 / Q9CQ71 / Replication protein A 14 kDa subunit / P35244* / replication protein A3*  / reaction / complex
 ENSMUSG00000034023 Fancd2 / Q80V62 / Fanconi anemia group D2 protein homolog / Q9BXW9* / Fanconi anemia complementation group D2*  / complex / reaction
 ENSMUSG00000032409 Atr / ATR serine/threonine kinase / Q13535*  / reaction / complex
 ENSMUSG00000000751 Rpa1 / Q8VEE4 / Replication protein A 70 kDa DNA-binding subunit / P27694* / replication protein A1*  / reaction / complex
 ENSMUSG00000028884 Rpa2 / replication protein A2 / P15927*  / complex / reaction
 ENSMUSG00000039187 Fanci / Q8K368 / Fanconi anemia group I protein homolog / Q9NVI1* / Fanconi anemia complementation group I*  / reaction / complex






 

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