ENSMUSG00000026803


Mus musculus

Features
Gene ID: ENSMUSG00000026803
  
Biological name :Ttf1
  
Synonyms : Q62187 / transcription termination factor, RNA polymerase I / Ttf1
  
Possible biological names infered from orthology : Q15361 / transcription termination factor 1
  
Species: Mus musculus
  
Chr. number: 2
Strand: 1
Band: A3
Gene start: 29060262
Gene end: 29087656
  
Corresponding Affymetrix probe sets: 10470649 (MoGene1.0st)   1420754_at (Mouse Genome 430 2.0 Array)   1426610_a_at (Mouse Genome 430 2.0 Array)   1440044_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000097809
NCBI entrez gene - 22130     See in Manteia.
MGI - MGI:105044
RefSeq - XM_006497852
RefSeq - NM_009442
RefSeq - XM_006497851
RefSeq Peptide - NP_033468
swissprot - Q62187
Ensembl - ENSMUSG00000026803
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 si:ch73-376l24.2ENSDARG00000092508Danio rerio
 si:ch73-376l24.3ENSDARG00000094043Danio rerio
 si:ch73-376l24.4ENSDARG00000093403Danio rerio
 si:ch73-376l24.6ENSDARG00000093999Danio rerio
 si:ch73-37h15.2ENSDARG00000094107Danio rerio
 ttf1ENSDARG00000091967Danio rerio
 ENSGALG00000027242Gallus gallus
 TTF1ENSG00000125482Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Dmtf1 / Q8CE22 / Cyclin-D-binding Myb-like transcription factor 1 / Q9Y222*ENSMUSG0000004250812
4932411N23Rik / RIKEN cDNA 4932411N23 gene / DMTF1* / Q9Y222* / cyclin D binding myb like transcription factor 1*ENSMUSG0000005867011


Protein motifs (from Interpro)
Interpro ID Name
 IPR001005  SANT/Myb domain
 IPR017877  Myb-like domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000183 chromatin silencing at rDNA TAS
 biological_processGO:0006338 chromatin remodeling IDA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006353 DNA-templated transcription, termination IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IBA
 biological_processGO:0006361 transcription initiation from RNA polymerase I promoter IDA
 biological_processGO:0006363 termination of RNA polymerase I transcription IDA
 biological_processGO:0008156 negative regulation of DNA replication IEA
 biological_processGO:0030154 cell differentiation IBA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005730 nucleolus IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding IBA
 molecular_functionGO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting IBA
 molecular_functionGO:0003677 DNA binding IDA
 molecular_functionGO:0003682 chromatin binding IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0043565 sequence-specific DNA binding IBA
 molecular_functionGO:0044212 transcription regulatory region DNA binding IBA


Pathways (from Reactome)
Pathway description
Surfactant metabolism
RNA Polymerase I Transcription Initiation
RNA Polymerase I Transcription Termination


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000019897 Ccdc59 / Q8R2N0 / Thyroid transcription factor 1-associated protein 26 / Q9P031* / coiled-coil domain containing 59*  / complex / reaction
 ENSMUSG00000013787 Ehmt2 / Q9Z148 / Histone-lysine N-methyltransferase EHMT2 / Q96KQ7* / euchromatic histone lysine methyltransferase 2*  / complex / reaction
 ENSMUSG00000004044 Cavin1 / O54724 / Caveolae-associated protein 1 / Q6NZI2*  / reaction / complex
 ENSMUSG00000054051 Ercc6 / ERCC excision repair 6, chromatin remodeling factor / P0DP91* / Q03468* / Q8N328*  / complex






 

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