MP:0000807 | abnormal hippocampus morphology | "absent or malformed deep lying structure of the cerebrum involved with memory storage and spatial navigation" [The Atlas of Mouse Development:ISBN 0-12-402035-6, MGI:Cls, J:38857] |
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Allelic Composition: Arem1Liuy/Y Genetic Background: involves: C57BL/6J * CBA
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MP:0001399 | hyperactivity | "general restlessness or excessive movement; more frequent movement from one place to another" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409, J:57125] |
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Allelic Composition: Arem1Liuy/Y Genetic Background: involves: C57BL/6J * CBA
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MP:0001405 | impaired coordination | "reduced ability to execute integrated movements of muscle" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Arem1Liuy/Y Genetic Background: involves: C57BL/6J * CBA
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MP:0001513 | limb grasping | "mice clasp front and/or hind feet almost immediately upon being lifted by tail" [cml:Cathleen M. Lutz , Mouse Genome Informatics Curator] |
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Allelic Composition: Arem1Liuy/Y Genetic Background: involves: C57BL/6J * CBA
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MP:0001876 | decreased inflammatory response | "less than expected response to injury, infection, or insult" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Ldlrtm1Her/Ldlrtm1Her,Nr5a2tm3.1Sjns/Nr5a2tm3.1Sjns Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J * C57BL/6N
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MP:0002118 | abnormal lipid homeostasis | "anomaly in the state of equilibrium in the body with respect to lipids in the fluids and tissues" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Arem1Liuy/Y Genetic Background: involves: C57BL/6J * CBA
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MP:0002574 | increased vertical activity | "greater than average time spent jumping or rearing " [J:72576, cwg:Carroll W. Goldsmith , Mouse Genome Informatics Curator] |
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Allelic Composition: Arem1Liuy/Y Genetic Background: involves: C57BL/6J * CBA
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MP:0002727 | decreased circulating insulin level | "less than normal levels of insulin in the blood" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, dlb:Donna Burkart , Mouse Genome Informatics Curator] |
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Allelic Composition: Ldlrtm1Her/Ldlrtm1Her,Nr5a2tm3.1Sjns/Nr5a2tm3.1Sjns Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J * C57BL/6N
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MP:0004889 | increased energy expenditure | "increase in the number of calories used per unit time or decrease in weight gain for a given amount of food eaten" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Ldlrtm1Her/Ldlrtm1Her,Nr5a2tm3.1Sjns/Nr5a2tm3.1Sjns Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J * C57BL/6N
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MP:0005292 | improved glucose tolerance | "better than the normal response to oral consumption or intravenous injection of specified amounts of glucose and indicative of insulin sensitivity; measured by determining whole blood or plasma sugar level in a fasting state before and after taking glucose at specified intervals" [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Ldlrtm1Her/Ldlrtm1Her,Nr5a2tm3.1Sjns/Nr5a2tm3.1Sjns Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J * C57BL/6N
Allelic Composition: Cers6tm1Arte/Cers6tm1Arte,Tg(Alb1-cre)7Gsc/0 Genetic Background: involves: C57BL/6N * FVB/N
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MP:0005659 | resistance to diet-induced obesity | "less likely to become excessively fat or to increase fat in the subcutaneous connective tissue as a result of consuming a diet geared to increase body fat " [cwg:Carroll-Ann W. Goldsmith, Mouse Genome Informatics curator] |
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Allelic Composition: Ldlrtm1Her/Ldlrtm1Her,Nr5a2tm3.1Sjns/Nr5a2tm3.1Sjns Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J * C57BL/6N
Allelic Composition: Cers6tm1Arte/Cers6tm1Arte,Tg(Alb1-cre)7Gsc/0 Genetic Background: involves: C57BL/6N * FVB/N
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MP:0005668 | decreased circulating leptin level | "less than the normal blood concentration of the peptide hormone secreted by white adipocytes and believed to regulate food intake and energy balance" [MeSH:National Library of Medicine - Medical Subject Headings, 2003, J:34751] |
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Allelic Composition: Ldlrtm1Her/Ldlrtm1Her,Nr5a2tm3.1Sjns/Nr5a2tm3.1Sjns Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J * C57BL/6N
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MP:0008034 | enhanced lipolysis | "increase in the rate of the hydrolysis of fat into free fatty acids " [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Ldlrtm1Her/Ldlrtm1Her,Nr5a2tm3.1Sjns/Nr5a2tm3.1Sjns Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J * C57BL/6N
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MP:0008912 | nervous | "increased, skittish, behavior induced by stimulation such as handling, touching or noise" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"] |
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Allelic Composition: Arem1Liuy/Y Genetic Background: involves: C57BL/6J * CBA
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MP:0008918 | microgliosis | "a proliferation or spread of microglia in the area of a degenerative lesion or damaged tissue" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Arem1Liuy/Y Genetic Background: involves: C57BL/6J * CBA
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MP:0009125 | decreased brown fat cell lipid droplet size | "reduction in the size of the multiple small droplets of triglycerides found in brown adipocytes" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Ldlrtm1Her/Ldlrtm1Her,Nr5a2tm3.1Sjns/Nr5a2tm3.1Sjns Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J * C57BL/6N
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MP:0009269 | decreased fat cell size | "reduction in the size of fat-storing cells found mostly in the abdominal cavity and subcutaneous tissue of mammals" [CL:0000449] |
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Allelic Composition: Ldlrtm1Her/Ldlrtm1Her,Nr5a2tm3.1Sjns/Nr5a2tm3.1Sjns Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J * C57BL/6N
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MP:0010025 | decreased total body fat amount | "less than the normal total amount of connective tissue composed of fat cells within the entire body" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Ldlrtm1Her/Ldlrtm1Her,Nr5a2tm3.1Sjns/Nr5a2tm3.1Sjns Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J * C57BL/6N
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MP:0010954 | abnormal cellular respiration | "anomaly in the enzymatic release of energy from organic compounds (especially carbohydrates and fats) which either requires oxygen (aerobic respiration) or does not (anaerobic respiration)" [GO:0045333] |
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Allelic Composition: Ldlrtm1Her/Ldlrtm1Her,Nr5a2tm3.1Sjns/Nr5a2tm3.1Sjns Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J * C57BL/6N
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MP:0011620 | abnormal habituation to a new environment | "anomaly in the process in which there is a progressive decline of behavioral response probability with an exposure to a new environment" [MGI:csmith] |
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Allelic Composition: Arem1Liuy/Y Genetic Background: involves: C57BL/6J * CBA
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MP:0012232 | abnormal ceramide level | |
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Allelic Composition: Ldlrtm1Her/Ldlrtm1Her,Nr5a2tm3.1Sjns/Nr5a2tm3.1Sjns Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J * C57BL/6N
Allelic Composition: Cers6tm1Arte/Cers6tm1Arte,Tg(Alb1-cre)7Gsc/0 Genetic Background: involves: C57BL/6N * FVB/N
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MP:0014171 | increased fatty acid oxidation | "increased rate or incidence of the process of removal of one or more electrons from a fatty acid, with or without the concomitant removal of a proton or protons, by reaction with an electron-accepting substance, by addition of oxygen or by removal of hydrogen" [GO:0019395] |
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Allelic Composition: Ldlrtm1Her/Ldlrtm1Her,Nr5a2tm3.1Sjns/Nr5a2tm3.1Sjns Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J * C57BL/6N
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