ENSG00000172292


Homo sapiens

Features
Gene ID: ENSG00000172292
  
Biological name :CERS6
  
Synonyms : ceramide synthase 6 / CERS6 / Q6ZMG9
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: 1
Band: q24.3
Gene start: 168455862
Gene end: 168775137
  
Corresponding Affymetrix probe sets: 212442_s_at (Human Genome U133 Plus 2.0 Array)   212446_s_at (Human Genome U133 Plus 2.0 Array)   235463_s_at (Human Genome U133 Plus 2.0 Array)   242019_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000306579
Ensembl peptide - ENSP00000376453
NCBI entrez gene - 253782     See in Manteia.
OMIM - 615336
RefSeq - NM_001256126
RefSeq - NM_203463
RefSeq Peptide - NP_001243055
RefSeq Peptide - NP_982288
swissprot - Q6ZMG9
Ensembl - ENSG00000172292
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cers6ENSDARG00000053583Danio rerio
 CERS6ENSGALG00000010902Gallus gallus
 Cers6ENSMUSG00000027035Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CERS5 / Q8N5B7 / ceramide synthase 5ENSG0000013962463
CERS4 / Q9HA82 / ceramide synthase 4ENSG0000009066141
CERS2 / Q96G23 / ceramide synthase 2ENSG0000014341840
CERS3 / Q8IU89 / ceramide synthase 3ENSG0000015422738


Protein motifs (from Interpro)
Interpro ID Name
 IPR001356  Homeobox domain
 IPR006634  TRAM/LAG1/CLN8 homology domain
 IPR009057  Homeobox-like domain superfamily
 IPR016439  Sphingosine N-acyltransferase Lag1/Lac1-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0030148 sphingolipid biosynthetic process TAS
 biological_processGO:0046513 ceramide biosynthetic process IBA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005783 endoplasmic reticulum IBA
 cellular_componentGO:0005789 endoplasmic reticulum membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031965 nuclear membrane IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding ISM
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0050291 sphingosine N-acyltransferase activity TAS


Pathways (from Reactome)
Pathway description
Sphingolipid de novo biosynthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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