ENSG00000139624


Homo sapiens

Features
Gene ID: ENSG00000139624
  
Biological name :CERS5
  
Synonyms : ceramide synthase 5 / CERS5 / Q8N5B7
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: -1
Band: q13.12
Gene start: 50129306
Gene end: 50167533
  
Corresponding Affymetrix probe sets: 224951_at (Human Genome U133 Plus 2.0 Array)   239491_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000449311
Ensembl peptide - ENSP00000448794
Ensembl peptide - ENSP00000450072
Ensembl peptide - ENSP00000325485
Ensembl peptide - ENSP00000369536
Ensembl peptide - ENSP00000389050
Ensembl peptide - ENSP00000407896
Ensembl peptide - ENSP00000442918
Ensembl peptide - ENSP00000446931
Ensembl peptide - ENSP00000446937
Ensembl peptide - ENSP00000447029
Ensembl peptide - ENSP00000447266
Ensembl peptide - ENSP00000447410
Ensembl peptide - ENSP00000448257
Ensembl peptide - ENSP00000448295
Ensembl peptide - ENSP00000448755
NCBI entrez gene - 91012     See in Manteia.
OMIM - 615335
RefSeq - XM_017020205
RefSeq - NM_001281731
RefSeq - NM_147190
RefSeq - XM_005269220
RefSeq - XM_006719687
RefSeq - XM_011538975
RefSeq - XM_017020202
RefSeq - XM_017020203
RefSeq - XM_017020204
RefSeq Peptide - NP_671723
RefSeq Peptide - NP_001268660
swissprot - H0YIG1
swissprot - Q8N5B7
swissprot - B4DQR7
swissprot - Q49AQ3
swissprot - F8VQZ6
swissprot - F8VSK7
swissprot - F8VXY1
swissprot - F8VY42
swissprot - F8W1K4
swissprot - F8W1N7
swissprot - F8W1Z3
swissprot - H0YHK2
swissprot - H0YHG4
swissprot - H0YI10
Ensembl - ENSG00000139624
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cers5ENSDARG00000002365Danio rerio
 CERS5ENSGALG00000039734Gallus gallus
 Cers5ENSMUSG00000023021Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CERS6 / Q6ZMG9 / ceramide synthase 6ENSG0000017229263
CERS4 / Q9HA82 / ceramide synthase 4ENSG0000009066142
CERS2 / Q96G23 / ceramide synthase 2ENSG0000014341841
CERS3 / Q8IU89 / ceramide synthase 3ENSG0000015422740


Protein motifs (from Interpro)
Interpro ID Name
 IPR001356  Homeobox domain
 IPR006634  TRAM/LAG1/CLN8 homology domain
 IPR009057  Homeobox-like domain superfamily
 IPR016439  Sphingosine N-acyltransferase Lag1/Lac1-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0006665 sphingolipid metabolic process IEA
 biological_processGO:0030148 sphingolipid biosynthetic process TAS
 biological_processGO:0046513 ceramide biosynthetic process IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005783 endoplasmic reticulum IBA
 cellular_componentGO:0005789 endoplasmic reticulum membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031965 nuclear membrane IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0050291 sphingosine N-acyltransferase activity IEA


Pathways (from Reactome)
Pathway description
Sphingolipid de novo biosynthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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