ENSG00000090661


Homo sapiens

Features
Gene ID: ENSG00000090661
  
Biological name :CERS4
  
Synonyms : ceramide synthase 4 / CERS4 / Q9HA82
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: 1
Band: p13.2
Gene start: 8206736
Gene end: 8262421
  
Corresponding Affymetrix probe sets: 218922_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000454122
Ensembl peptide - ENSP00000453796
Ensembl peptide - ENSP00000453815
Ensembl peptide - ENSP00000251363
Ensembl peptide - ENSP00000452753
Ensembl peptide - ENSP00000452910
Ensembl peptide - ENSP00000452920
Ensembl peptide - ENSP00000453388
Ensembl peptide - ENSP00000453509
NCBI entrez gene - 79603     See in Manteia.
OMIM - 615334
RefSeq - XM_017027305
RefSeq - NM_024552
RefSeq - XM_011528290
RefSeq - XM_011528291
RefSeq - XM_011528292
RefSeq - XM_011528293
RefSeq - XM_011528294
RefSeq - XM_011528295
RefSeq - XM_017027303
RefSeq - XM_017027304
RefSeq Peptide - NP_078828
swissprot - H0YKS3
swissprot - H0YLY3
swissprot - H0YMY6
swissprot - H0YN04
swissprot - H0YNR6
swissprot - H0YKC9
swissprot - H0YKR4
swissprot - Q9HA82
Ensembl - ENSG00000090661
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cers4aENSDARG00000031387Danio rerio
 cers4bENSDARG00000018619Danio rerio
 ENSGALG00000043352Gallus gallus
 ENSGALG00000000406Gallus gallus
 Cers4ENSMUSG00000008206Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CERS2 / Q96G23 / ceramide synthase 2ENSG0000014341846
CERS3 / Q8IU89 / ceramide synthase 3ENSG0000015422743
CERS5 / Q8N5B7 / ceramide synthase 5ENSG0000013962442
CERS6 / Q6ZMG9 / ceramide synthase 6ENSG0000017229241


Protein motifs (from Interpro)
Interpro ID Name
 IPR001356  Homeobox domain
 IPR006634  TRAM/LAG1/CLN8 homology domain
 IPR009057  Homeobox-like domain superfamily
 IPR016439  Sphingosine N-acyltransferase Lag1/Lac1-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0030148 sphingolipid biosynthetic process TAS
 biological_processGO:0046513 ceramide biosynthetic process IBA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005783 endoplasmic reticulum IBA
 cellular_componentGO:0005789 endoplasmic reticulum membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031965 nuclear membrane IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0050291 sphingosine N-acyltransferase activity TAS


Pathways (from Reactome)
Pathway description
Sphingolipid de novo biosynthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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