Manteia - Molecule gene

ENSMUSG00000027288

Mus musculus

Features

Gene ID:	ENSMUSG00000027288

Biological name :	Zfp106

Synonyms :	Zfp106 / zinc finger protein 106

Possible biological names infered from orthology :	Q9H2Y7 / ZNF106

Species:	Mus musculus

Chr. number:	2
Strand:	-1
Band:	E5
Gene start:	120506820
Gene end:	120563843

Corresponding Affymetrix probe sets:	10486522 (MoGene1.0st) 1425097_a_at (Mouse Genome 430 2.0 Array) 1425098_at (Mouse Genome 430 2.0 Array) 1425331_at (Mouse Genome 430 2.0 Array) 1425332_at (Mouse Genome 430 2.0 Array) 1450190_at (Mouse Genome 430 2.0 Array)

Cross references:	Ensembl peptide - ENSMUSP00000128995 Ensembl peptide - ENSMUSP00000128291 Ensembl peptide - ENSMUSP00000132902 Ensembl peptide - ENSMUSP00000055602 Ensembl peptide - ENSMUSP00000126939 Ensembl peptide - ENSMUSP00000127803 NCBI entrez gene - 20402 See in Manteia. MGI - MGI:1270153 RefSeq - XM_006499044 RefSeq - NM_011743 RefSeq - XM_006499042 RefSeq Peptide - NP_035873 swissprot - E9Q7S1 swissprot - E9PVH6 swissprot - F6UL00 swissprot - R4GML0 swissprot - F6QFS1 swissprot - F6SID8 Ensembl - ENSMUSG00000027288

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Ortholog name	ID	Species
znf106a	ENSDARG00000016651	Danio rerio
ZNF106	ENSGALG00000009081	Gallus gallus
Q9H2Y7	ENSG00000103994	Homo sapiens

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
Fbxw7 / Q8VBV4 / F-box/WD repeat-containing protein 7 / Q969H0* / F-box and WD repeat domain containing 7*	ENSMUSG00000028086	8
Traf7 / TNF receptor-associated factor 7 / Q6Q0C0*	ENSMUSG00000052752	7
Q5SUS0 / Fbxw10 / F-box/WD repeat-containing protein 10 / CDRT1* / O95170* / Q5XX13* / CMT1A duplicated region transcript 1* / F-box and WD repeat domain containing 10*	ENSMUSG00000090173	7
Btrc / Q3ULA2 / F-box/WD repeat-containing protein 1A / Q9Y297* / beta-transducin repeat containing E3 ubiquitin protein ligase*	ENSMUSG00000025217	7
Fbxw11 / Q5SRY7 / F-box/WD repeat-containing protein 11 / Q9UKB1* / F-box and WD repeat domain containing 11*	ENSMUSG00000020271	6
Wdr86 / WD repeat domain 86 / Q86TI4*	ENSMUSG00000055235	5
Fbxw2 / F-box and WD repeat domain containing 2 / Q9UKT8*	ENSMUSG00000035949	4

Protein motifs (from Interpro)

Interpro ID	Name
IPR001680	WD40 repeat
IPR013087	Zinc finger C2H2-type
IPR015943	WD40/YVTN repeat-like-containing domain superfamily
IPR017986	WD40-repeat-containing domain
IPR018391	Pyrrolo-quinoline quinone beta-propeller repeat
IPR036322	WD40-repeat-containing domain superfamily

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
molecular_function	GO:0003676	nucleic acid binding	IEA
molecular_function	GO:0005515	protein binding	IEA

Pathways (from Reactome)

Pathway description

No match

Phenotype (from MGI, Zfin or HPO)

ID	Phenotype	Definition	Genetic BG
MP:0000160	kyphosis	"forward curvature of the spine, characterized by extensive flexion. " [J:62023, J:66943, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, cml:Cathleen M. Lutz , Mouse Genome Informatics Curator]	Show Allelic Composition: Kdm6a^tm2.1Kaig/Kdm6a^tm2.1Kaig Genetic Background: involves: 129 * C57BL/6
MP:0000194	hypercalcemia	"abnormally high concentration of calcium ions in the circulating blood " [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]	Show Allelic Composition: Kmt5b^{tm1a(KOMP)Wtsi}/Kmt5b^{tm1a(KOMP)Wtsi} Genetic Background: B6JTyr;B6N-Kmt5b^{tm1a(KOMP)Wtsi}/Wtsi
MP:0000745	tremors	"repetitive, cyclical movements of the body or a body part; usually involuntary, but can also manifest in response to an attempt at movement" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]	Show Allelic Composition: Kdm6a^tm2.1Kaig/Kdm6a^tm2.1Kaig Genetic Background: involves: 129 * C57BL/6
MP:0000759	abnormal skeletal muscle morphology	"anomalous structure of any of the striated muscle fibers connected at either or both extremeties with the bony framework of the body" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Trim25^tm1Mura/Trim25⁺,Usp15^L749R/Usp15⁺ Genetic Background: involves: 129S1/SvImJ * 129S4/SvJae * C57BL/6J Allelic Composition: Zfp106^{tm1b(KOMP)Wtsi}/Zfp106^{tm1b(KOMP)Wtsi} Genetic Background: involves: C57BL/6N
MP:0000937	abnormal motor neuron morphology	"malformation or absence of cells that innervate an effector (muscle or glandular) tissue; responsible for transmission of motor impulses" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:60159]	Show Allelic Composition: Zfp106^{tm1b(KOMP)Wtsi}/Zfp106^{tm1b(KOMP)Wtsi} Genetic Background: involves: C57BL/6N Allelic Composition: Tg(Mnx1-Zfp106,-EGFP)2Blk/0,Zfp106^{tm1b(KOMP)Wtsi}/Zfp106^{tm1b(KOMP)Wtsi} Genetic Background: involves: C57BL/6N
MP:0000938	motor neuron degeneration	"retrogressive impairment of function or destruction of the cells that innervate an effector (muscle or glandular) tissue" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Kdm6a^tm2.1Kaig/Kdm6a^tm2.1Kaig Genetic Background: involves: 129 * C57BL/6
MP:0000939	reduced motor neuron number	"fewer than normal numbers of cells that innervate an effector (muscle or glandular) tissue" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:60159]	Show Allelic Composition: Trim25^tm1Mura/Trim25⁺,Usp15^L749R/Usp15⁺ Genetic Background: involves: 129S1/SvImJ * 129S4/SvJae * C57BL/6J Allelic Composition: Zfp106^{tm1b(KOMP)Wtsi}/Zfp106^{tm1b(KOMP)Wtsi} Genetic Background: involves: C57BL/6N
MP:0000955	abnormal spinal cord morphology	"malformation or disorganization of the cylindrical tissue of the vertebral canal that extends from the medulla oblongata to the conus medullaris" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Kdm6a^tm2.1Kaig/Kdm6a^tm2.1Kaig Genetic Background: involves: 129 * C57BL/6
MP:0000964	small dorsal root ganglia	"reduced size of the dorsal root ganglia" [J:17123]	Show Allelic Composition: Kdm6a^tm2.1Kaig/Kdm6a^tm2.1Kaig Genetic Background: involves: 129 * C57BL/6
MP:0001021	small L4 ganglion	"reduced size of L4 ganglion" [J:17792]	Show Allelic Composition: Kdm6a^tm2.1Kaig/Kdm6a^tm2.1Kaig Genetic Background: involves: 129 * C57BL/6
MP:0001024	small L5 ganglion	"reduced size of L5 ganglion" [J:17792]	Show Allelic Composition: Kdm6a^tm2.1Kaig/Kdm6a^tm2.1Kaig Genetic Background: involves: 129 * C57BL/6
MP:0001259	abnormal body weight	"anomaly in average weight compared to the norm" [cwg:Carroll W. Goldsmith, Mouse Genome Informatics Curator]	Show Allelic Composition: Zfp106^{tm1b(KOMP)Wtsi}/Zfp106^{tm1b(KOMP)Wtsi} Genetic Background: involves: C57BL/6N Allelic Composition: Tg(Mnx1-Zfp106,-EGFP)2Blk/0,Zfp106^{tm1b(KOMP)Wtsi}/Zfp106^{tm1b(KOMP)Wtsi} Genetic Background: involves: C57BL/6N
MP:0001262	decreased body weight	"lower than normal average weight " [J:61295]	Show Allelic Composition: Kmt5b^{tm1a(KOMP)Wtsi}/Kmt5b^{tm1a(KOMP)Wtsi} Genetic Background: B6JTyr;B6N-Kmt5b^{tm1a(KOMP)Wtsi}/Wtsi
MP:0001263	weight loss	"progressive reduction of body weight below normal average for age" [J:45400]	Show Allelic Composition: Kdm6a^tm2.1Kaig/Kdm6a^tm2.1Kaig Genetic Background: involves: 129 * C57BL/6
MP:0001402	hypoactivity	"reduced movement from one place to another" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, J:64289]	Show Allelic Composition: Kdm6a^tm2.1Kaig/Kdm6a^tm2.1Kaig Genetic Background: involves: 129 * C57BL/6
MP:0001405	impaired coordination	"reduced ability to execute integrated movements of muscle" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]	Show Allelic Composition: Kdm6a^tm2.1Kaig/Kdm6a^tm2.1Kaig Genetic Background: involves: 129 * C57BL/6
MP:0001406	abnormal gait	"unusual or distinctive way of walking" [J:65038]	Show Allelic Composition: Kdm6a^tm2.1Kaig/Kdm6a^tm2.1Kaig Genetic Background: involves: 129 * C57BL/6 Allelic Composition: Zfp106^{tm1a(KOMP)Wtsi}/Zfp106^{tm1a(KOMP)Wtsi} Genetic Background: B6JTyr;B6N-Zfp106^{tm1a(KOMP)Wtsi}/Wtsi
MP:0001513	limb grasping	"mice clasp front and/or hind feet almost immediately upon being lifted by tail" [cml:Cathleen M. Lutz , Mouse Genome Informatics Curator]	Show Allelic Composition: Kdm6a^tm2.1Kaig/Kdm6a^tm2.1Kaig Genetic Background: involves: 129 * C57BL/6
MP:0001524	impaired limb coordination	"reduced ability to organize limb movements to execute complex maneuvers, such as walking" [J:64962, MGI:CLS, J:17123]	Show Allelic Composition: Kdm6a^tm2.1Kaig/Kdm6a^tm2.1Kaig Genetic Background: involves: 129 * C57BL/6
MP:0001973	increased thermal nociceptive threshold	"a greater than average point at which thermal pain sensation is first detectable" [What s Wrong With My Mouse?:ISBN 0-471-31639-3, J:17194]	Show Allelic Composition: Zfp106^{tm1a(KOMP)Wtsi}/Zfp106^{tm1a(KOMP)Wtsi} Genetic Background: B6JTyr;B6N-Zfp106^{tm1a(KOMP)Wtsi}/Wtsi
MP:0002066	abnormal motor capabilities/coordination/movement	"altered ability to coordinate voluntary movement or repetitive, compulsive movements" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Zfp106^{tm1b(KOMP)Wtsi}/Zfp106^{tm1b(KOMP)Wtsi} Genetic Background: involves: C57BL/6N Allelic Composition: Tg(Mnx1-Zfp106,-EGFP)2Blk/0,Zfp106^{tm1b(KOMP)Wtsi}/Zfp106^{tm1b(KOMP)Wtsi} Genetic Background: involves: C57BL/6N
MP:0002083	premature death	"death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Kdm6a^tm2.1Kaig/Kdm6a^tm2.1Kaig Genetic Background: involves: 129 * C57BL/6
MP:0002106	abnormal muscle physiology	"anomolous function of the muscle, not due to an anatomical defect" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Kdm6a^tm2.1Kaig/Kdm6a^tm2.1Kaig Genetic Background: involves: 129 * C57BL/6
MP:0002183	gliosis	"increased growth pattern of neuroglia in a damaged area of the brain or spinal cord" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Kdm6a^tm2.1Kaig/Kdm6a^tm2.1Kaig Genetic Background: involves: 129 * C57BL/6
MP:0002229	CNS neurodegeneration	"a retrogressive impairment of function or destruction of neural tissue" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Kdm6a^tm2.1Kaig/Kdm6a^tm2.1Kaig Genetic Background: involves: 129 * C57BL/6
MP:0002883	chromatolysis	"the dissolution of the granules of chromophil substance in a nerve cell body that may occur in injured cells or axons" [dlb:Donna Burkart , Mouse Genome Informatics Curator]	Show Allelic Composition: Kdm6a^tm2.1Kaig/Kdm6a^tm2.1Kaig Genetic Background: involves: 129 * C57BL/6
MP:0003081	abnormal soleus morphology	"anomaly in the the superficial flat broad muscle of the calf that is responsible for plantar flexion of the foot" [Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8, smb:Susan M. Bello, Mouse Genome Informatics Curator]	Show Allelic Composition: Kdm6a^tm2.1Kaig/Kdm6a^tm2.1Kaig Genetic Background: involves: 129 * C57BL/6
MP:0003082	abnormal gastrocnemius morphology	"anomaly in the the two-headed large muscle of the posterior portion of the lower hindleg, the most superficial of the calf muscles" [smb:Susan M. Bello, Mouse Genome Informatics Curator, Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8]	Show Allelic Composition: Kdm6a^tm2.1Kaig/Kdm6a^tm2.1Kaig Genetic Background: involves: 129 * C57BL/6
MP:0003186	abnormal redox activity	"defect in the processes that maintain the redox environment of a cell or compartment within a cell " [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Kdm6a^tm2.1Kaig/Kdm6a^tm2.1Kaig Genetic Background: involves: 129 * C57BL/6
MP:0003354	astrocytosis	"a proliferation or spread of astrocytes in the area of a degenerative lesion or damaged tissue" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]	Show Allelic Composition: Kdm6a^tm2.1Kaig/Kdm6a^tm2.1Kaig Genetic Background: involves: 129 * C57BL/6
MP:0004087	abnormal muscle fiber morphology	"malformed or poorly developed muscle fibers, the cylindrical multinucleated muscle cells that contract when stimulated" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Zfp106^{tm1b(KOMP)Wtsi}/Zfp106^{tm1b(KOMP)Wtsi} Genetic Background: involves: C57BL/6N Allelic Composition: Tg(Mnx1-Zfp106,-EGFP)2Blk/0,Zfp106^{tm1b(KOMP)Wtsi}/Zfp106^{tm1b(KOMP)Wtsi} Genetic Background: involves: C57BL/6N
MP:0004145	abnormal muscle electrophysiology	"anomaly in the function of the musculature as it relates to electrical phenomena" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Kdm6a^tm2.1Kaig/Kdm6a^tm2.1Kaig Genetic Background: involves: 129 * C57BL/6
MP:0004262	abnormal physical strength	"altered ability of an organism to exert force on physical objects or of the body to support its load" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Trim25^tm1Mura/Trim25⁺,Usp15^L749R/Usp15⁺ Genetic Background: involves: 129S1/SvImJ * 129S4/SvJae * C57BL/6J Allelic Composition: Zfp106^{tm1b(KOMP)Wtsi}/Zfp106^{tm1b(KOMP)Wtsi} Genetic Background: involves: C57BL/6N
MP:0005150	cachexia	"general weight loss and wasting occurring in the course of chronic disease" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Trim25^tm1Mura/Trim25⁺,Usp15^L749R/Usp15⁺ Genetic Background: involves: 129S1/SvImJ * 129S4/SvJae * C57BL/6J Allelic Composition: Zfp106^{tm1b(KOMP)Wtsi}/Zfp106^{tm1b(KOMP)Wtsi} Genetic Background: involves: C57BL/6N
MP:0005356	positive geotaxis	"mice, when placed on a downward on a slanting grid, walk down without turning around, or exhibit a delay in turning around, whereas wild type mice will always turn around and walk upward" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, J:79604]	Show Allelic Composition: Kdm6a^tm2.1Kaig/Kdm6a^tm2.1Kaig Genetic Background: involves: 129 * C57BL/6
MP:0005404	abnormal axon morphology	"anomaly in the structure of the single process of a nerve cell that normally conducts impulses away from the cell body" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Kdm6a^tm2.1Kaig/Kdm6a^tm2.1Kaig Genetic Background: involves: 129 * C57BL/6
MP:0005405	axon degeneration	"retrogressive pathologic change in the single process of a nerve cell " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Kdm6a^tm2.1Kaig/Kdm6a^tm2.1Kaig Genetic Background: involves: 129 * C57BL/6
MP:0005562	decreased mean corpuscular hemoglobin	"less than the average levels of hemoglobin contained in an erythrocyte" [RGD:Rat Genome Database submission, Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Kmt5b^{tm1a(KOMP)Wtsi}/Kmt5b^{tm1a(KOMP)Wtsi} Genetic Background: B6JTyr;B6N-Kmt5b^{tm1a(KOMP)Wtsi}/Wtsi
MP:0006036	abnormal mitochondrial physiology		Show Allelic Composition: Kdm6a^tm2.1Kaig/Kdm6a^tm2.1Kaig Genetic Background: involves: 129 * C57BL/6
MP:0006404	abnormal lumbar dorsal root ganglion morphology	"any structural anomaly of the group of nerve cell bodies located on the dorsal spinal roots within the vertebral column at the level of the lumbar vertebrae" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]	Show Allelic Composition: Kdm6a^tm2.1Kaig/Kdm6a^tm2.1Kaig Genetic Background: involves: 129 * C57BL/6
MP:0008918	microgliosis	"a proliferation or spread of microglia in the area of a degenerative lesion or damaged tissue" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Kdm6a^tm2.1Kaig/Kdm6a^tm2.1Kaig Genetic Background: involves: 129 * C57BL/6
MP:0009199	abnormal external male genitalia morphology	"any structural anomaly of the external masculine genital organs, including the penis and scrotum" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]	Show Allelic Composition: Zfp106^{tm1a(KOMP)Wtsi}/Zfp106^{tm1a(KOMP)Wtsi} Genetic Background: B6JTyr;B6N-Zfp106^{tm1a(KOMP)Wtsi}/Wtsi
MP:0009403	increased variability of skeletal muscle fiber size	"greater range or dispersion within a distribution of skeletal muscle fiber size within a muscle compared to controls" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Kdm6a^tm2.1Kaig/Kdm6a^tm2.1Kaig Genetic Background: involves: 129 * C57BL/6
MP:0009404	centrally nucleated skeletal muscle fibers	"cell nuclei are located at a position in the center of the skeletal myofiber, instead of their normal location at the periphery of the fiber; may be indicative of centronuclear myopathy" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Kdm6a^tm2.1Kaig/Kdm6a^tm2.1Kaig Genetic Background: involves: 129 * C57BL/6
MP:0009406	decreased skeletal muscle fiber number	"decreased number of the skeletal muscle fibers, the large multinucleated cells that make up the skeletal muscles" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Kdm6a^tm2.1Kaig/Kdm6a^tm2.1Kaig Genetic Background: involves: 129 * C57BL/6
MP:0009409	abnormal skeletal muscle fiber type ratio	"deviation from the standard ratios of fiber types in a given skeletal muscle compared to control samples" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Kdm6a^tm2.1Kaig/Kdm6a^tm2.1Kaig Genetic Background: involves: 129 * C57BL/6
MP:0009412	skeletal muscle fiber degeneration	"pathological deterioration of skeletal muscle fiber tissue, often accompanied by loss of function" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Trim25^tm1Mura/Trim25⁺,Usp15^L749R/Usp15⁺ Genetic Background: involves: 129S1/SvImJ * 129S4/SvJae * C57BL/6J Allelic Composition: Zfp106^{tm1b(KOMP)Wtsi}/Zfp106^{tm1b(KOMP)Wtsi} Genetic Background: involves: C57BL/6N
MP:0009413	skeletal muscle fiber atrophy	"a wasting of skeletal muscle fibers resulting in a derangement of the skeletal muscle fibers; occurs with age, immobilization, weightlessness, malnutrition or denervation" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Kdm6a^tm2.1Kaig/Kdm6a^tm2.1Kaig Genetic Background: involves: 129 * C57BL/6 Allelic Composition: Zfp106^em1Blk/Zfp106^em1Blk Genetic Background: Not Specified Allelic Composition: Zfp106^{tm1b(KOMP)Wtsi}/Zfp106^{tm1b(KOMP)Wtsi} Genetic Background: involves: C57BL/6N
MP:0009417	skeletal muscle atrophy	"a wasting of skeletal muscle tissue resulting in a derangement of the muscle fibers; occurs with age, immobilization, weightlessness, malnutrition or denervation" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]	Show Allelic Composition: Kdm6a^tm2.1Kaig/Kdm6a^tm2.1Kaig Genetic Background: involves: 129 * C57BL/6
MP:0009419	skeletal muscle fibrosis	"formation of fibrous tissue within skeletal muscle as a result of repair or a reactive process" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]	Show Allelic Composition: Kdm6a^tm2.1Kaig/Kdm6a^tm2.1Kaig Genetic Background: involves: 129 * C57BL/6
MP:0009422	decreased gastrocnemius weight	"reduction in the weight of the two-headed large muscle of the posterior portion of the lower hindleg, the most superficial of the calf muscles" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]	Show Allelic Composition: Kdm6a^tm2.1Kaig/Kdm6a^tm2.1Kaig Genetic Background: involves: 129 * C57BL/6
MP:0009426	decreased soleus weight	"reduction in the weight of the superficial flat broad muscle of the calf that is responsible for plantar flexion of the foot" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]	Show Allelic Composition: Kdm6a^tm2.1Kaig/Kdm6a^tm2.1Kaig Genetic Background: involves: 129 * C57BL/6
MP:0009428	decreased tibialis anterior weight	"redcution in the weight of the muscle of the shin that is responsible for dorsiflexion and inversion of the foot" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]	Show Allelic Composition: Kdm6a^tm2.1Kaig/Kdm6a^tm2.1Kaig Genetic Background: involves: 129 * C57BL/6
MP:0010053	decreased grip strength	"reduced ability to grasp and hold objects, often measured as time spent hanging from an object or wire" [ISBN:0471316393 "Crawley, JN, What s Wrong with my Mouse: Behavioral Phenotyping of Transgenic and Knockout Mice"]	Show Allelic Composition: Kdm6a^tm2.1Kaig/Kdm6a^tm2.1Kaig Genetic Background: involves: 129 * C57BL/6 Allelic Composition: Zfp106^em1Blk/Zfp106^em1Blk Genetic Background: Not Specified Allelic Composition: Zfp106^{tm1b(KOMP)Wtsi}/Zfp106^{tm1b(KOMP)Wtsi} Genetic Background: involves: C57BL/6N
MP:0010956	abnormal mitochondrial ATP synthesis coupled electron transport	"anomaly in the transfer of electrons through a series of electron donors and acceptors, generating energy that is ultimately used for synthesis of ATP, as it occurs in the mitochondrial inner membrane and mediated by multisubunit enzyme complexes known as complex I-IV" [GO:0042775, MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Kdm6a^tm2.1Kaig/Kdm6a^tm2.1Kaig Genetic Background: involves: 129 * C57BL/6
MP:0013182	increased spinal cord apoptosis	"increase in the number of cells of the neural tube undergoing programmed cell death" [MGI:anna]	Show Allelic Composition: Kdm6a^tm2.1Kaig/Kdm6a^tm2.1Kaig Genetic Background: involves: 129 * C57BL/6

Interacting proteins (from Reactome)

Interactor ID

Name

Interaction type

No match

1 s.

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