ENSMUSG00000052752


Mus musculus

Features
Gene ID: ENSMUSG00000052752
  
Biological name :Traf7
  
Synonyms : TNF receptor-associated factor 7 / Traf7
  
Possible biological names infered from orthology : Q6Q0C0
  
Species: Mus musculus
  
Chr. number: 17
Strand: -1
Band: A3.3
Gene start: 24508562
Gene end: 24527938
  
Corresponding Affymetrix probe sets: 10448593 (MoGene1.0st)   1424320_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000135267
Ensembl peptide - ENSMUSP00000135288
Ensembl peptide - ENSMUSP00000135339
Ensembl peptide - ENSMUSP00000135341
Ensembl peptide - ENSMUSP00000135456
Ensembl peptide - ENSMUSP00000135874
Ensembl peptide - ENSMUSP00000069334
Ensembl peptide - ENSMUSP00000085812
Ensembl peptide - ENSMUSP00000134759
Ensembl peptide - ENSMUSP00000134808
Ensembl peptide - ENSMUSP00000134946
Ensembl peptide - ENSMUSP00000134970
Ensembl peptide - ENSMUSP00000135127
Ensembl peptide - ENSMUSP00000135583
Ensembl peptide - ENSMUSP00000135586
Ensembl peptide - ENSMUSP00000135845
NCBI entrez gene - 224619     See in Manteia.
MGI - MGI:3042141
RefSeq - NM_001172114
RefSeq - NM_153792
RefSeq - NM_001172113
RefSeq Peptide - NP_001165584
RefSeq Peptide - NP_001165585
RefSeq Peptide - NP_722487
swissprot - Q8C2K8
swissprot - F8WJF7
swissprot - H3BJ15
swissprot - H3BJD9
swissprot - H3BJF9
swissprot - H3BJU4
swissprot - H3BK82
swissprot - H3BKC7
swissprot - H3BKC9
swissprot - H3BKN1
swissprot - H3BKZ1
swissprot - H3BLM6
swissprot - H3BLQ3
Ensembl - ENSMUSG00000052752
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 traf7ENSDARG00000060207Danio rerio
 TRAF7ENSGALG00000005767Gallus gallus
 TRAF7ENSG00000131653Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Zfp106 / zinc finger protein 106 / Q9H2Y7* / ZNF106*ENSMUSG0000002728820
Btrc / Q3ULA2 / F-box/WD repeat-containing protein 1A / Q9Y297* / beta-transducin repeat containing E3 ubiquitin protein ligase*ENSMUSG0000002521717
Fbxw11 / Q5SRY7 / F-box/WD repeat-containing protein 11 / Q9UKB1* / F-box and WD repeat domain containing 11*ENSMUSG0000002027117
Fbxw7 / Q8VBV4 / F-box/WD repeat-containing protein 7 / Q969H0* / F-box and WD repeat domain containing 7*ENSMUSG0000002808617
Q5SUS0 / Fbxw10 / F-box/WD repeat-containing protein 10 / CDRT1* / O95170* / Q5XX13* / CMT1A duplicated region transcript 1* / F-box and WD repeat domain containing 10*ENSMUSG0000009017313
Fbxw2 / F-box and WD repeat domain containing 2 / Q9UKT8*ENSMUSG0000003594912
Wdr86 / WD repeat domain 86 / Q86TI4*ENSMUSG0000005523512


Protein motifs (from Interpro)
Interpro ID Name
 IPR001293  Zinc finger, TRAF-type
 IPR001680  WD40 repeat
 IPR001841  Zinc finger, RING-type
 IPR008974  TRAF-like
 IPR011042  Six-bladed beta-propeller, TolB-like
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR017907  Zinc finger, RING-type, conserved site
 IPR017986  WD40-repeat-containing domain
 IPR019775  WD40 repeat, conserved site
 IPR020472  G-protein beta WD-40 repeat
 IPR027370  RING-type zinc-finger, LisH dimerisation motif
 IPR036322  WD40-repeat-containing domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000185 activation of MAPKKK activity IEA
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0043410 positive regulation of MAPK cascade IEA
 biological_processGO:2001235 positive regulation of apoptotic signaling pathway IEA
 cellular_componentGO:0000151 ubiquitin ligase complex IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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