ENSG00000131653


Homo sapiens

Features
Gene ID: ENSG00000131653
  
Biological name :TRAF7
  
Synonyms : Q6Q0C0 / TNF receptor associated factor 7 / TRAF7
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 16
Strand: 1
Band: p13.3
Gene start: 2155698
Gene end: 2178129
  
Corresponding Affymetrix probe sets: 223029_s_at (Human Genome U133 Plus 2.0 Array)   223030_at (Human Genome U133 Plus 2.0 Array)   223031_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000478515
Ensembl peptide - ENSP00000479297
Ensembl peptide - ENSP00000318944
Ensembl peptide - ENSP00000456034
Ensembl peptide - ENSP00000457735
NCBI entrez gene - 84231     See in Manteia.
OMIM - 606692
RefSeq - NM_032271
RefSeq - XM_011522700
RefSeq - XM_005255627
RefSeq Peptide - NP_115647
swissprot - A0A087WUB0
swissprot - Q6Q0C0
swissprot - H3BUP4
swissprot - H3BR17
Ensembl - ENSG00000131653
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 traf7ENSDARG00000060207Danio rerio
 TRAF7ENSGALG00000005767Gallus gallus
 Traf7ENSMUSG00000052752Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9H2Y7 / ZNF106 / zinc finger protein 106ENSG0000010399420
FBXW7 / Q969H0 / F-box and WD repeat domain containing 7ENSG0000010967017
BTRC / Q9Y297 / beta-transducin repeat containing E3 ubiquitin protein ligaseENSG0000016616717
FBXW11 / Q9UKB1 / F-box and WD repeat domain containing 11ENSG0000007280316
FBXW10 / Q5XX13 / F-box and WD repeat domain containing 10ENSG0000017193113
CDRT1 / O95170 / CMT1A duplicated region transcript 1ENSG0000024132212
FBXW2 / Q9UKT8 / F-box and WD repeat domain containing 2ENSG0000011940212
WDR86 / Q86TI4 / WD repeat domain 86ENSG0000018726010


Protein motifs (from Interpro)
Interpro ID Name
 IPR001293  Zinc finger, TRAF-type
 IPR001680  WD40 repeat
 IPR001841  Zinc finger, RING-type
 IPR008974  TRAF-like
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR017907  Zinc finger, RING-type, conserved site
 IPR017986  WD40-repeat-containing domain
 IPR019775  WD40 repeat, conserved site
 IPR020472  G-protein beta WD-40 repeat
 IPR027370  RING-type zinc-finger, LisH dimerisation motif
 IPR036322  WD40-repeat-containing domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000185 activation of MAPKKK activity IDA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006915 apoptotic process IDA
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0043410 positive regulation of MAPK cascade IDA
 biological_processGO:2001235 positive regulation of apoptotic signaling pathway IMP
 cellular_componentGO:0000151 ubiquitin ligase complex IDA
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IDA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008270 zinc ion binding NAS
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr