ENSG00000171931


Homo sapiens

Features
Gene ID: ENSG00000171931
  
Biological name :FBXW10
  
Synonyms : F-box and WD repeat domain containing 10 / FBXW10 / Q5XX13
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: 1
Band: p11.2
Gene start: 18744024
Gene end: 18779349
  
Corresponding Affymetrix probe sets: 223870_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000306937
Ensembl peptide - ENSP00000310382
Ensembl peptide - ENSP00000379025
Ensembl peptide - ENSP00000463552
NCBI entrez gene - 10517     See in Manteia.
OMIM - 611679
RefSeq - XM_017024021
RefSeq - NM_001267585
RefSeq - NM_001267586
RefSeq - XM_011523625
RefSeq - XM_011523626
RefSeq - XM_017024020
RefSeq Peptide - NP_001254514
RefSeq Peptide - NP_001254515
swissprot - J3QLH9
swissprot - Q5XX13
Ensembl - ENSG00000171931
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 fbxw10ENSDARG00000086484Danio rerio
 ENSGALG00000044567Gallus gallus
 Fbxw10ENSMUSG00000090173Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CDRT1 / O95170 / CMT1A duplicated region transcript 1ENSG0000024132266
Q9H2Y7 / ZNF106 / zinc finger protein 106ENSG0000010399412
FBXW7 / Q969H0 / F-box and WD repeat domain containing 7ENSG0000010967011
FBXW2 / Q9UKT8 / F-box and WD repeat domain containing 2ENSG0000011940210
BTRC / Q9Y297 / beta-transducin repeat containing E3 ubiquitin protein ligaseENSG0000016616710
FBXW11 / Q9UKB1 / F-box and WD repeat domain containing 11ENSG000000728039
TRAF7 / Q6Q0C0 / TNF receptor associated factor 7ENSG000001316538
WDR86 / Q86TI4 / WD repeat domain 86ENSG000001872606


Protein motifs (from Interpro)
Interpro ID Name
 IPR001680  WD40 repeat
 IPR011042  Six-bladed beta-propeller, TolB-like
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR017986  WD40-repeat-containing domain
 IPR019775  WD40 repeat, conserved site
 IPR020472  G-protein beta WD-40 repeat
 IPR036047  F-box-like domain superfamily
 IPR036322  WD40-repeat-containing domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000209 protein polyubiquitination TAS
 biological_processGO:0043687 post-translational protein modification TAS
 cellular_componentGO:0005829 cytosol TAS
 molecular_functionGO:0004842 ubiquitin-protein transferase activity TAS
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
Association of TriC/CCT with target proteins during biosynthesis
Neddylation
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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