ENSMUSG00000027361


Mus musculus

Features
Gene ID: ENSMUSG00000027361
  
Biological name :Gabpb1
  
Synonyms : GA-binding protein subunit beta-1 / Gabpb1 / Q00420
  
Possible biological names infered from orthology : GA binding protein transcription factor beta subunit 1 / Q06547
  
Species: Mus musculus
  
Chr. number: 2
Strand: -1
Band: F1
Gene start: 126627442
Gene end: 126676337
  
Corresponding Affymetrix probe sets: 10487252 (MoGene1.0st)   1419761_a_at (Mouse Genome 430 2.0 Array)   1436232_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000117355
Ensembl peptide - ENSMUSP00000106055
Ensembl peptide - ENSMUSP00000118358
Ensembl peptide - ENSMUSP00000037673
Ensembl peptide - ENSMUSP00000087177
Ensembl peptide - ENSMUSP00000099516
Ensembl peptide - ENSMUSP00000099517
Ensembl peptide - ENSMUSP00000106054
NCBI entrez gene - 14391     See in Manteia.
MGI - MGI:95611
RefSeq - XM_017315588
RefSeq - NM_010249
RefSeq - NM_207669
RefSeq - XM_006498755
RefSeq - XM_006498756
RefSeq - XM_006498757
RefSeq - XM_006498758
RefSeq - XM_006498759
RefSeq - XM_006498760
RefSeq - XM_006498761
RefSeq - XM_006498762
RefSeq - XM_006498764
RefSeq - NM_001271467
RefSeq - NM_001271468
RefSeq - NM_001271470
RefSeq - NM_001271492
RefSeq Peptide - NP_997552
RefSeq Peptide - NP_001258396
RefSeq Peptide - NP_001258397
RefSeq Peptide - NP_001258399
RefSeq Peptide - NP_001258421
RefSeq Peptide - NP_034379
swissprot - Q3UT69
swissprot - Q00420
swissprot - Q3US22
swissprot - A2AQ72
swissprot - A2AQ71
Ensembl - ENSMUSG00000027361
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gabpb1ENSDARG00000023659Danio rerio
 GABPB1ENSGALG00000023440Gallus gallus
 GABPB1ENSG00000104064Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Gabpb2 / P81069 / GA-binding protein subunit beta-2 / Q8TAK5* / GA binding protein transcription factor beta subunit 2*ENSMUSG0000003876659
Q9D2X0 / Ankrd39 / Ankyrin repeat domain-containing protein 39 / Q53RE8* / ankyrin repeat domain 39*ENSMUSG0000007961011


Protein motifs (from Interpro)
Interpro ID Name
 IPR002110  Ankyrin repeat
 IPR020683  Ankyrin repeat-containing domain
 IPR036770  Ankyrin repeat-containing domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IBA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005654 nucleoplasm ISO
 cellular_componentGO:0036464 cytoplasmic ribonucleoprotein granule ISO
 molecular_functionGO:0003700 DNA-binding transcription factor activity IBA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0044212 transcription regulatory region DNA binding IBA
 molecular_functionGO:0046982 protein heterodimerization activity ISO


Pathways (from Reactome)
Pathway description
Transcriptional activation of mitochondrial biogenesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0009434 paraparesis "a weakness affecting lower limbs" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Hoxd13spdh/Hoxd13+
Genetic Background: B6C3Fe a/a-Hoxd13spdh/J

 MP:0011098 complete embryonic lethality during organogenesis "death of all organisms of a given genotype in a population between embryo turning and the completion of organogenesis (Mus: E9 to less than E14)" [MGI:csmith]
Show

Allelic Composition: Hoxd13spdh/Hoxd13+
Genetic Background: B6C3Fe a/a-Hoxd13spdh/J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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