ENSMUSG00000038766


Mus musculus

Features
Gene ID: ENSMUSG00000038766
  
Biological name :Gabpb2
  
Synonyms : GA-binding protein subunit beta-2 / Gabpb2 / P81069
  
Possible biological names infered from orthology : GA binding protein transcription factor beta subunit 2 / Q8TAK5
  
Species: Mus musculus
  
Chr. number: 3
Strand: -1
Band: F2.1
Gene start: 95181766
Gene end: 95217916
  
Corresponding Affymetrix probe sets: 10500103 (MoGene1.0st)   1440289_at (Mouse Genome 430 2.0 Array)   1440868_at (Mouse Genome 430 2.0 Array)   1443942_at (Mouse Genome 430 2.0 Array)   1455110_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000096470
Ensembl peptide - ENSMUSP00000102822
Ensembl peptide - ENSMUSP00000102827
Ensembl peptide - ENSMUSP00000121283
NCBI entrez gene - 213054     See in Manteia.
MGI - MGI:95612
RefSeq - XM_017319515
RefSeq - NM_029885
RefSeq - NM_172512
RefSeq - XM_011240058
RefSeq - XM_011240059
RefSeq - XM_011240060
RefSeq - XM_011240061
RefSeq - XM_006501250
RefSeq - XM_006501251
RefSeq - XM_006501252
RefSeq - XM_006501253
RefSeq Peptide - NP_766100
RefSeq Peptide - NP_084161
swissprot - P81069
swissprot - Q8C2T8
Ensembl - ENSMUSG00000038766
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gabpb2aENSDARG00000007943Danio rerio
 gabpb2bENSDARG00000054344Danio rerio
 GABPB2ENSGALG00000026734Gallus gallus
 GABPB2ENSG00000143458Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Gabpb1 / Q00420 / GA-binding protein subunit beta-1 / Q06547* / GA binding protein transcription factor beta subunit 1*ENSMUSG0000002736155
Q9D2X0 / Ankrd39 / Ankyrin repeat domain-containing protein 39 / Q53RE8* / ankyrin repeat domain 39*ENSMUSG0000007961010


Protein motifs (from Interpro)
Interpro ID Name
 IPR002110  Ankyrin repeat
 IPR020683  Ankyrin repeat-containing domain
 IPR036770  Ankyrin repeat-containing domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IBA
 cellular_componentGO:0005634 nucleus IBA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IBA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0042803 protein homodimerization activity IDA
 molecular_functionGO:0044212 transcription regulatory region DNA binding IBA
 molecular_functionGO:0046982 protein heterodimerization activity ISO


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002494 increased IgM "greater than normal immunoglobulin class M level" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Gfi1btm1Tmo/Gfi1btm1Tmo
Genetic Background: B6.129-Gfi1btm1Tmo

 MP:0005154 increased B cell proliferation "greater than the normal response by B cells to grow and divide in response to stimuli " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Gfi1btm1Tmo/Gfi1btm1Tmo
Genetic Background: B6.129-Gfi1btm1Tmo

 MP:0008481 increased spleen germinal center number "greater number of spleen secondary B follicles where rapid B-cell proliferation, somatic hypermutation, and selection for antigen binding occurs" [PMID:17495967]
Show

Allelic Composition: Gfi1btm1Tmo/Gfi1btm1Tmo
Genetic Background: B6.129-Gfi1btm1Tmo

 MP:0008499 increased IgG1 level "greater than normal immunoglobulin class G1 level" [MGI:tmeehan "Terry Meehan, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Gfi1btm1Tmo/Gfi1btm1Tmo
Genetic Background: B6.129-Gfi1btm1Tmo

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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