ENSMUSG00000028455


Mus musculus

Features
Gene ID: ENSMUSG00000028455
  
Biological name :Stoml2
  
Synonyms : Q99JB2 / Stomatin-like protein 2, mitochondrial / Stoml2
  
Possible biological names infered from orthology : Q9UJZ1 / stomatin like 2
  
Species: Mus musculus
  
Chr. number: 4
Strand: -1
Band: A5
Gene start: 43027690
Gene end: 43031710
  
Corresponding Affymetrix probe sets: 10512443 (MoGene1.0st)   1448774_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000117586
Ensembl peptide - ENSMUSP00000123478
Ensembl peptide - ENSMUSP00000118465
Ensembl peptide - ENSMUSP00000030169
NCBI entrez gene - 66592     See in Manteia.
MGI - MGI:1913842
RefSeq - NM_023231
RefSeq Peptide - NP_075720
swissprot - A2AG39
swissprot - F6WI02
swissprot - A2AG41
swissprot - Q99JB2
Ensembl - ENSMUSG00000028455
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 stoml2ENSDARG00000103135Danio rerio
 ENSGALG00000002064Gallus gallus
 Q9UJZ1ENSG00000165283Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q6PE84 / Stoml3 / stomatin (Epb7.2)-like 3 / Q8TAV4* / stomatin like 3*ENSMUSG0000002774423
Stom / P54116 / Erythrocyte band 7 integral membrane protein / P27105* / stomatin*ENSMUSG0000002688021
Nphs2 / Q91X05 / Podocin / Q9NP85* / NPHS2, podocin*ENSMUSG0000002660220
Stoml1 / stomatin like 1 / Q9UBI4*ENSMUSG0000003233318


Protein motifs (from Interpro)
Interpro ID Name
 IPR001107  Band 7 domain
 IPR001972  Stomatin family
 IPR032435  Band 7, C-terminal extension
 IPR036013  Band 7/SPFH domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006851 mitochondrial calcium ion transmembrane transport IEA
 biological_processGO:0006874 cellular calcium ion homeostasis IEA
 biological_processGO:0007005 mitochondrion organization IEA
 biological_processGO:0010876 lipid localization IMP
 biological_processGO:0010918 positive regulation of mitochondrial membrane potential IEA
 biological_processGO:0032623 interleukin-2 production IMP
 biological_processGO:0034982 mitochondrial protein processing IMP
 biological_processGO:0035710 CD4-positive, alpha-beta T cell activation IMP
 biological_processGO:0042776 mitochondrial ATP synthesis coupled proton transport IMP
 biological_processGO:0050852 T cell receptor signaling pathway IEA
 biological_processGO:0051259 protein complex oligomerization IEA
 biological_processGO:0090297 positive regulation of mitochondrial DNA replication IEA
 biological_processGO:1900210 positive regulation of cardiolipin metabolic process IEA
 biological_processGO:1990046 stress-induced mitochondrial fusion IMP
 cellular_componentGO:0001772 immunological synapse IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005743 mitochondrial inner membrane ISO
 cellular_componentGO:0005758 mitochondrial intermembrane space ISO
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0008180 COP9 signalosome IEA
 cellular_componentGO:0015629 actin cytoskeleton IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0019897 extrinsic component of plasma membrane IEA
 cellular_componentGO:0042101 T cell receptor complex IEA
 cellular_componentGO:0045121 membrane raft ISO
 molecular_functionGO:0008289 lipid binding IEA
 molecular_functionGO:0051020 GTPase binding IEA
 molecular_functionGO:1901612 cardiolipin binding IEA


Pathways (from Reactome)
Pathway description
Processing of SMDT1


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000033918 Parl / Q5XJY4 / Presenilins-associated rhomboid-like protein, mitochondrial P-beta / Q9H300* / AC131160.1* / presenilin associated rhomboid like*  / complex
 ENSMUSG00000026775 O88967 / Yme1l1 / YME1-like 1 (S. cerevisiae) / Q96TA2* / YME1 like 1 ATPase*  / complex






 

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