ENSMUSG00000029151


Mus musculus

Features
Gene ID: ENSMUSG00000029151
  
Biological name :Slc30a3
  
Synonyms : Mus musculus solute carrier family 30 (zinc transporter), member 3 (Slc30a3), transcript variant 2, mRNA. / P97441 / Slc30a3
  
Possible biological names infered from orthology : Q99726 / solute carrier family 30 member 3
  
Species: Mus musculus
  
Chr. number: 5
Strand: -1
Band: B1
Gene start: 31086106
Gene end: 31108237
  
Corresponding Affymetrix probe sets: 10529068 (MoGene1.0st)   1460654_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000031037
Ensembl peptide - ENSMUSP00000144098
Ensembl peptide - ENSMUSP00000144566
Ensembl peptide - ENSMUSP00000144574
Ensembl peptide - ENSMUSP00000144295
Ensembl peptide - ENSMUSP00000144353
NCBI entrez gene - 22784     See in Manteia.
MGI - MGI:1345280
RefSeq - XM_006503865
RefSeq - NM_001347323
RefSeq - NM_011773
RefSeq - XM_006503864
RefSeq Peptide - NP_001334252
RefSeq Peptide - NP_035903
swissprot - S4R166
swissprot - S4R169
swissprot - P97441
swissprot - S4R2M0
swissprot - S4R2S4
swissprot - S4R1P0
swissprot - Q3TMQ7
Ensembl - ENSMUSG00000029151
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 slc30a2ENSDARG00000021305Danio rerio
 Q99726ENSG00000115194Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q2HJ10 / Slc30a2 / solute carrier family 30 (zinc transporter), member 2 / Q9BRI3* / solute carrier family 30 member 2*ENSMUSG0000002883649
Q8BGG0 / Slc30a8 / Zinc transporter 8 / Q8IWU4* / solute carrier family 30 member 8*ENSMUSG0000002231541
O35149 / Slc30a4 / Zinc transporter 4 / O14863* / solute carrier family 30 member 4*ENSMUSG0000000580233
Q60738 / Slc30a1 / solute carrier family 30 (zinc transporter), member 1 / Q9Y6M5* / solute carrier family 30 member 1*ENSMUSG0000003743422
Q3UVU3 / Slc30a10 / Zinc transporter 10 / Q6XR72* / solute carrier family 30 member 10*ENSMUSG0000002661421


Protein motifs (from Interpro)
Interpro ID Name
 IPR002524  Cation efflux protein
 IPR027469  Cation efflux transmembrane domain superfamily
 IPR036837  Cation efflux protein, cytoplasmic domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006812 cation transport IEA
 biological_processGO:0006829 zinc ion transport TAS
 biological_processGO:0010312 detoxification of zinc ion TAS
 biological_processGO:0032119 sequestering of zinc ion TAS
 biological_processGO:0051050 positive regulation of transport IGI
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:0061088 regulation of sequestering of zinc ion IEA
 biological_processGO:0071577 zinc ion transmembrane transport IEA
 biological_processGO:0098655 cation transmembrane transport IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005764 lysosome IEA
 cellular_componentGO:0005765 lysosomal membrane IEA
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005770 late endosome IEA
 cellular_componentGO:0005886 plasma membrane IBA
 cellular_componentGO:0008021 synaptic vesicle IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0030672 synaptic vesicle membrane TAS
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0031902 late endosome membrane IEA
 cellular_componentGO:0043005 neuron projection IEA
 cellular_componentGO:0045202 synapse IEA
 molecular_functionGO:0005385 zinc ion transmembrane transporter activity TAS
 molecular_functionGO:0008324 cation transmembrane transporter activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002761 abnormal hippocampal mossy fiber morphology "absence or misprojection of axons of neuronal cells in the dentate gyrus" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, J:4978]
Show

Allelic Composition: Sp5tm1Rbe/Sp5tm1Rbe,T/T+
Genetic Background: involves: 129P2/Ola * C57BL/6J

 MP:0003329 amyloid beta deposits 
Show

Allelic Composition: Lamc1Gt(Ex183)Byg/Lamc1Gt(Ex183)Byg
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0004769 abnormal synaptic vesicle morphology "any structural anomaly of the small, membrane bound sacs that contain various neurotransmitter molecules that are concentrated at pre-synaptic membranes and release the neurotransmitters by fusion of these vesicles with the presynaptic membrane, followed by exocytosis of their contents" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Sp5tm1Rbe/Sp5tm1Rbe,T/T+
Genetic Background: involves: 129P2/Ola * C57BL/6J

 MP:0009615 abnormal zinc homeostasis "anomaly in the processes involved in the maintenance of an internal equilibrium of zinc that normally is a cofactor in many proteins" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Sp5tm1Rbe/Sp5tm1Rbe,T/T+
Genetic Background: involves: 129P2/Ola * C57BL/6J

 MP:0009617 decreased brain zinc level "reduction in the amount of zinc present in the brain tissue" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Sp5tm1Rbe/Sp5tm1Rbe,T/T+
Genetic Background: involves: 129P2/Ola * C57BL/6J

Allelic Composition: Slc30a3tm1Rpa/Slc30a3tm1Rpa,Tg(APPSWE)2576Kha/0
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6 * SJL

Allelic Composition: Slc30a3tm1Rpa/Slc30a3+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Slc30a3tm1Rpa/Slc30a3tm1Rpa
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6 * SJL

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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