ENSMUSG00000037434


Mus musculus

Features
Gene ID: ENSMUSG00000037434
  
Biological name :Slc30a1
  
Synonyms : Q60738 / Slc30a1 / solute carrier family 30 (zinc transporter), member 1
  
Possible biological names infered from orthology : Q9Y6M5 / solute carrier family 30 member 1
  
Species: Mus musculus
  
Chr. number: 1
Strand: 1
Band: H6
Gene start: 191906767
Gene end: 191913247
  
Corresponding Affymetrix probe sets: 10352777 (MoGene1.0st)   1422786_at (Mouse Genome 430 2.0 Array)   1436164_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000042410
Ensembl peptide - ENSMUSP00000124176
NCBI entrez gene - 22782     See in Manteia.
MGI - MGI:1345281
RefSeq - NM_009579
RefSeq Peptide - NP_033605
swissprot - F6TRQ3
swissprot - Q3UM63
swissprot - Q60738
Ensembl - ENSMUSG00000037434
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 slc30a1aENSDARG00000005463Danio rerio
 slc30a1bENSDARG00000053896Danio rerio
 SLC30A1ENSGALG00000009858Gallus gallus
 Q9Y6M5ENSG00000170385Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q3UVU3 / Slc30a10 / Zinc transporter 10 / Q6XR72* / solute carrier family 30 member 10*ENSMUSG0000002661434
Q2HJ10 / Slc30a2 / solute carrier family 30 (zinc transporter), member 2 / Q9BRI3* / solute carrier family 30 member 2*ENSMUSG0000002883619
Q8BGG0 / Slc30a8 / Zinc transporter 8 / Q8IWU4* / solute carrier family 30 member 8*ENSMUSG0000002231518
P97441 / Slc30a3 / Mus musculus solute carrier family 30 (zinc transporter), member 3 (Slc30a3), transcript variant 2, mRNA. / Q99726* / solute carrier family 30 member 3*ENSMUSG0000002915117
O35149 / Slc30a4 / Zinc transporter 4 / O14863* / solute carrier family 30 member 4*ENSMUSG0000000580216


Protein motifs (from Interpro)
Interpro ID Name
 IPR002524  Cation efflux protein
 IPR027469  Cation efflux transmembrane domain superfamily
 IPR036837  Cation efflux protein, cytoplasmic domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001701 in utero embryonic development IMP
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006812 cation transport IEA
 biological_processGO:0006829 zinc ion transport IDA
 biological_processGO:0006874 cellular calcium ion homeostasis IDA
 biological_processGO:0006882 cellular zinc ion homeostasis IDA
 biological_processGO:0010043 response to zinc ion IBA
 biological_processGO:0046929 negative regulation of neurotransmitter secretion IEA
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:0061088 regulation of sequestering of zinc ion IBA
 biological_processGO:0065009 regulation of molecular function IEA
 biological_processGO:0070509 calcium ion import IEA
 biological_processGO:0070574 cadmium ion transmembrane transport IEA
 biological_processGO:0071577 zinc ion transmembrane transport IEA
 biological_processGO:0071584 negative regulation of zinc ion transmembrane import IDA
 biological_processGO:0071585 detoxification of cadmium ion IEA
 biological_processGO:0090281 negative regulation of calcium ion import IDA
 biological_processGO:0098655 cation transmembrane transport IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005886 plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030315 T-tubule IEA
 cellular_componentGO:0031965 nuclear membrane IEA
 molecular_functionGO:0005385 zinc ion transmembrane transporter activity IEA
 molecular_functionGO:0008324 cation transmembrane transporter activity IEA
 molecular_functionGO:0019855 calcium channel inhibitor activity IDA


Pathways (from Reactome)
Pathway description
Zinc efflux and compartmentalization by the SLC30 family


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001730 embryonic growth arrest "the cessation of development beyond a particular stage" [J:17509]
Show

Allelic Composition: Tnfaip3tm1Ama/Tnfaip3tm1Ama
Genetic Background: Not Specified

 MP:0001923 reduced female fertility "reduced ability of female to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409]
Show

Allelic Composition: Tnfaip3tm1Ama/Tnfaip3tm1Ama
Genetic Background: Not Specified

 MP:0011098 complete embryonic lethality during organogenesis "death of all organisms of a given genotype in a population between embryo turning and the completion of organogenesis (Mus: E9 to less than E14)" [MGI:csmith]
Show

Allelic Composition: Tnfaip3tm1Ama/Tnfaip3tm1Ama
Genetic Background: Not Specified

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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