| MP:0000048 | abnormal stria vascularis | "anomalous structure of the layer of highly vascularized pigmented granular cells on the outer wall of the cochlear duct" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Mybpc3tm1.1Jse/Mybpc3tm1.1Jse
Genetic Background: Not Specified
|
| MP:0000519 | hydronephrosis | "dilation of the pelvis and calices of one or both kidneys" [J:56641] |
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Allelic Composition: Mybpc3tm1.1Jse/Mybpc3tm1.1Jse
Genetic Background: Not Specified
|
| MP:0000534 | abnormal ureter morphology | "anomalous structure of the tube that conducts the urine from the renal pelvis to the bladder" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Mybpc3tm1.1Jse/Mybpc3tm1.1Jse
Genetic Background: Not Specified
|
| MP:0000745 | tremors | "repetitive, cyclical movements of the body or a body part; usually involuntary, but can also manifest in response to an attempt at movement" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Scarb2tm1Psa/Scarb2tm1Psa
Genetic Background: involves: 129P2/OlaHsd * C57BL/6N
|
| MP:0000753 | paralysis | "loss of power of voluntary movement in a muscle through injury or disease of its nerve supply" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Scarb2tm1Psa/Scarb2tm1Psa
Genetic Background: involves: 129P2/OlaHsd * C57BL/6N
|
| MP:0000921 | demyelination | "loss of the myelin sheath without loss of axons or fiber tracts" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Mybpc3tm1.1Jse/Mybpc3tm1.1Jse
Genetic Background: Not Specified
|
| MP:0001078 | abnormal phrenic nerve | "malformed or misprojection of motor and sensory neuron axons to the diaphragm and other tissues" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:60159] |
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Allelic Composition: Mybpc3tm1.1Jse/Mybpc3tm1.1Jse
Genetic Background: Not Specified
|
| MP:0001106 | abnormal Schwann cell | "malformed or absent cells which form the insulating myelin sheaths of peripheral axons" [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Mybpc3tm1.1Jse/Mybpc3tm1.1Jse
Genetic Background: Not Specified
|
| MP:0001262 | decreased body weight | "lower than normal average weight " [J:61295] |
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Allelic Composition: Scarb2tm1Psa/Scarb2tm1Psa
Genetic Background: involves: 129P2/OlaHsd * C57BL/6N
|
| MP:0001270 | distended abdomen | "abdomen appears curved outward or swollen; can be due to skeletal axial defects, enlarged visceral organs or megacolon" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Mybpc3tm1.1Jse/Mybpc3tm1.1Jse
Genetic Background: Not Specified
|
| MP:0001426 | polydipsia | "excessive thirst that is relatively prolonged" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Mybpc3tm1.1Jse/Mybpc3tm1.1Jse
Genetic Background: Not Specified
|
| MP:0001513 | limb grasping | "mice clasp front and/or hind feet almost immediately upon being lifted by tail" [cml:Cathleen M. Lutz , Mouse Genome Informatics Curator] |
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Allelic Composition: Scarb2tm1Psa/Scarb2tm1Psa
Genetic Background: involves: 129P2/OlaHsd * C57BL/6N
|
| MP:0001762 | polyuria | "increased volume of urine produced and excreted" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, smb:Susan M Bello, Mouse Genome Informatics Curator] |
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Allelic Composition: Mybpc3tm1.1Jse/Mybpc3tm1.1Jse
Genetic Background: Not Specified
|
| MP:0001967 | deafness | "inability to hear" [J:57651] |
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Allelic Composition: Mybpc3tm1.1Jse/Mybpc3tm1.1Jse
Genetic Background: Not Specified
|
| MP:0002083 | premature death | "death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Mybpc3tm1.1Jse/Mybpc3tm1.1Jse
Genetic Background: Not Specified
Allelic Composition: Scarb2tm1Psa/Scarb2tm1Psa
Genetic Background: involves: 129P2/OlaHsd * C57BL/6N
|
| MP:0002229 | CNS neurodegeneration | "a retrogressive impairment of function or destruction of neural tissue" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Scarb2tm1Psa/Scarb2tm1Psa
Genetic Background: involves: 129P2/OlaHsd * C57BL/6N
|
| MP:0002857 | cochlear ganglion degeneration | "loss of neural cell bodies in the group of nerve cell bodies that conveys auditory sensation from the organ of Corti to the hindbrain" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Mybpc3tm1.1Jse/Mybpc3tm1.1Jse
Genetic Background: Not Specified
|
| MP:0002871 | albuminuria | "presence of excess albumin in the urine" [RGD:Rat Genome Database submission, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Mybpc3tm1.1Jse/Mybpc3tm1.1Jse
Genetic Background: Not Specified
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| MP:0002882 | abnormal neuron | "anomaly in the functional cells of the nervous system that receive, conduct, and transmit impulses " [MeSH:National Library of Medicine - Medical Subject Headings, 2003] |
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Allelic Composition: Scarb2tm1Psa/Scarb2tm1Psa
Genetic Background: involves: 129P2/OlaHsd * C57BL/6N
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| MP:0002895 | abnormal otolithic membrane | "malformations of the gelatinous membrane surmounting the acoustic maculae of the saccule and utricle and containing minute calciferous particles (otoliths)" [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Mybpc3tm1.1Jse/Mybpc3tm1.1Jse
Genetic Background: Not Specified
|
| MP:0002978 | absent otoliths | "absence of the crystalline calciferous particles adhering to the otolithic membrane" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Mybpc3tm1.1Jse/Mybpc3tm1.1Jse
Genetic Background: Not Specified
|
| MP:0002988 | decreased urine osmolarity | "reduction in the concentration of ions in the urine compared to normal" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, J:83000] |
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Allelic Composition: Mybpc3tm1.1Jse/Mybpc3tm1.1Jse
Genetic Background: Not Specified
|
| MP:0003354 | astrocytosis | "a proliferation or spread of astrocytes in the area of a degenerative lesion or damaged tissue" [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Scarb2tm1Psa/Scarb2tm1Psa
Genetic Background: involves: 129P2/OlaHsd * C57BL/6N
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| MP:0003630 | abnormal urothelium | "malformation of the mucus lining in organs of the urinary tract, consisting in the bladder of three to seven cell layers" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:95622] |
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Allelic Composition: Mybpc3tm1.1Jse/Mybpc3tm1.1Jse
Genetic Background: Not Specified
|
| MP:0003632 | abnormal nervous system morphology | |
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Allelic Composition: Mybpc3tm1.1Jse/Mybpc3tm1.1Jse
Genetic Background: Not Specified
Allelic Composition: Scarb2tm1Psa/Scarb2tm1Psa
Genetic Background: involves: 129P2/OlaHsd * C57BL/6N
|
| MP:0003870 | decreased urine glucose level | "a greater level of excretion of glucose in the urine compared to the normal state" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, RGD:Rat Genome Database submission] |
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Allelic Composition: Mybpc3tm1.1Jse/Mybpc3tm1.1Jse
Genetic Background: Not Specified
|
| MP:0004363 | stria vascularis degeneration | "degeneration or loss of the stratified, secretory epithelium which lines the upper part of the cochlear spiral ligament and maintains potassium ion homeostasis in the endolymph" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Mybpc3tm1.1Jse/Mybpc3tm1.1Jse
Genetic Background: Not Specified
|
| MP:0004366 | abnormal strial marginal cells | "any structural abnormality in the polarized columnar cells of epithelial origin which cover the lateral surface of the cochlear duct, secrete potassium ions and form a continuous sheet in contact with the endolymph; marginal cells form extensive interdigitations with the basal and intermediate cells in the normal adult stria" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Mybpc3tm1.1Jse/Mybpc3tm1.1Jse
Genetic Background: Not Specified
|
| MP:0004368 | abnormal stria vascularis vasculature | "any structural anomaly of the blood vessels supplying the stria vascularis in the cochlea of the inner ear" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Mybpc3tm1.1Jse/Mybpc3tm1.1Jse
Genetic Background: Not Specified
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| MP:0004398 | cochlear inner hair cell degeneration | "degeneration or loss of the single row of flask-shaped inner hair sensory cells of the organ of Corti" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Mybpc3tm1.1Jse/Mybpc3tm1.1Jse
Genetic Background: Not Specified
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| MP:0004404 | cochlear outer hair cell degeneration | "degeneration or loss of the columnar outer hair sensory cells of the organ of Corti" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Mybpc3tm1.1Jse/Mybpc3tm1.1Jse
Genetic Background: Not Specified
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| MP:0004410 | absent endocochlear potential | "absence of the electrical potential difference between the endolymphatic and perilymphatic compartments of the cochlea, indicating a primary defect in fluid homeostasis of the inner ear" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Mybpc3tm1.1Jse/Mybpc3tm1.1Jse
Genetic Background: Not Specified
|
| MP:0004411 | decreased endocochlear potential | "reduction of the electrical potential difference between the endolymphatic and perilymphatic compartments of the cochlea" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Mybpc3tm1.1Jse/Mybpc3tm1.1Jse
Genetic Background: Not Specified
|
| MP:0004438 | abnormal vestibular hair cell physiology | "anomalies in processes pertinent to the integrated function of the sensory epithelium of the maculae and cristae in the membranous labyrinth of the inner ear" [J:100987, MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Mybpc3tm1.1Jse/Mybpc3tm1.1Jse
Genetic Background: Not Specified
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| MP:0004736 | abnormal distortion product otoacoustic emission | "any abnormality in the sound produced by the cochlea in response to stimulation with 2 simultaneous tones of different frequencies; this measurement is particularly useful in assessing the functional state of OHCs" [eMedicine:http://www.emedicine.com/ent/topic372.htm, MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Mybpc3tm1.1Jse/Mybpc3tm1.1Jse
Genetic Background: Not Specified
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| MP:0004738 | abnormal brainstem auditory evoked potential | "anomaly in the electrical activity generated in response to short tone bursts; may be used to evaluate sensorineural hearing function" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator", MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Mybpc3tm1.1Jse/Mybpc3tm1.1Jse
Genetic Background: Not Specified
|
| MP:0004740 | sensorineural hearing loss | "a form of progressive hearing loss due to a lesion of the auditory division of cranial nerve VIII or the inner ear" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Mybpc3tm1.1Jse/Mybpc3tm1.1Jse
Genetic Background: Not Specified
|
| MP:0004924 | abnormal behavior | "anomalies in the actions, reactions, or performance of an organism in response to external or internal stimuli compared to controls" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Scarb2tm1Psa/Scarb2tm1Psa
Genetic Background: involves: 129P2/OlaHsd * C57BL/6N
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| MP:0005584 | abnormal enzyme/coenzyme activity | "altered ability of any of these proteins, or their cofactors, to act as catalysts to induce chemical changes in other substances" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Scarb2tm1Psa/Scarb2tm1Psa
Genetic Background: involves: 129P2/OlaHsd * C57BL/6N
|
| MP:0006359 | absent startle reflex | "failure to respond to variable stimuli, often auditory; usually measured by amplitude of whole body flinch" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator", MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Mybpc3tm1.1Jse/Mybpc3tm1.1Jse
Genetic Background: Not Specified
|
| MP:0008918 | microgliosis | "a proliferation or spread of microglia in the area of a degenerative lesion or damaged tissue" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Scarb2tm1Psa/Scarb2tm1Psa
Genetic Background: involves: 129P2/OlaHsd * C57BL/6N
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| MP:0011305 | dilated kidney calyx | "an expansion in the lumen volume or area of any of the branches of the renal pelvis that surround each renal papilla and collect urine" [MGI:anna] |
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Allelic Composition: Mybpc3tm1.1Jse/Mybpc3tm1.1Jse
Genetic Background: Not Specified
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| MP:0011418 | leukocyturia | "presence of white blood cells in the urine" [MGI:anna] |
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Allelic Composition: Mybpc3tm1.1Jse/Mybpc3tm1.1Jse
Genetic Background: Not Specified
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| MP:0011426 | abnormal ureter smooth muscle morphology | "any structural anomaly of the smooth muscle tissue surrounding the epithelium of the ureter" [MGI:anna] |
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Allelic Composition: Mybpc3tm1.1Jse/Mybpc3tm1.1Jse
Genetic Background: Not Specified
|
| MP:0011487 | abnormal ureteropelvic junction morphology | "any structural anomaly of the junction between the ureter and the renal pelvis of the kidney" [MGI:anna, MGI:csmith] |
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Allelic Composition: Mybpc3tm1.1Jse/Mybpc3tm1.1Jse
Genetic Background: Not Specified
|
| MP:0011491 | ureteropelvic junction obstruction | "a partial or total blockage of the flow of urine through the junction of the renal pelvis and the proximal ureter" [MGI:anna] |
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Allelic Composition: Mybpc3tm1.1Jse/Mybpc3tm1.1Jse
Genetic Background: Not Specified
|
