ENSMUSG00000029474


Mus musculus

Features
Gene ID: ENSMUSG00000029474
  
Biological name :Rnf34
  
Synonyms : E3 ubiquitin-protein ligase RNF34 / Q99KR6 / Rnf34
  
Possible biological names infered from orthology : Q969K3 / ring finger protein 34
  
Species: Mus musculus
  
Chr. number: 5
Strand: 1
Band: F
Gene start: 122850048
Gene end: 122871291
  
Corresponding Affymetrix probe sets: 10525452 (MoGene1.0st)   1415791_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000143603
Ensembl peptide - ENSMUSP00000031434
NCBI entrez gene - 80751     See in Manteia.
MGI - MGI:2153340
RefSeq - NM_030564
RefSeq - XM_006530512
RefSeq Peptide - NP_085041
swissprot - A0A0G2JGK8
swissprot - Q99KR6
Ensembl - ENSMUSG00000029474
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rnf34aENSDARG00000038300Danio rerio
 rnf34bENSDARG00000054036Danio rerio
 RNF34ENSGALG00000004190Gallus gallus
 RNF34ENSG00000170633Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Rffl / Q6ZQM0 / E3 ubiquitin-protein ligase rififylin / Q8WZ73* / AC004223.3* / ring finger and FYVE like domain containing E3 ubiquitin protein ligase*ENSMUSG0000002069642


Protein motifs (from Interpro)
Interpro ID Name
 IPR001841  Zinc finger, RING-type
 IPR011011  Zinc finger, FYVE/PHD-type
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR036361  SAP domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006511 ubiquitin-dependent protein catabolic process IEA
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0016567 protein ubiquitination ISO
 biological_processGO:0035872 nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway IEA
 biological_processGO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process IEA
 biological_processGO:0070417 cellular response to cold IMP
 biological_processGO:0070936 protein K48-linked ubiquitination IEA
 biological_processGO:1901797 negative regulation of signal transduction by p53 class mediator IEA
 biological_processGO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors IEA
 biological_processGO:2000374 regulation of oxygen metabolic process IMP
 biological_processGO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis IEA
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005737 cytoplasm ISS
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0012505 endomembrane system IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016604 nuclear body IEA
 cellular_componentGO:0016607 nuclear speck IEA
 molecular_functionGO:0002039 p53 binding IEA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0031625 ubiquitin protein ligase binding IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0061630 ubiquitin protein ligase activity IEA
 molecular_functionGO:1901981 phosphatidylinositol phosphate binding IEA


Pathways (from Reactome)
Pathway description
Regulation of TP53 Degradation
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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