ENSMUSG00000029552


Mus musculus

Features
Gene ID: ENSMUSG00000029552
  
Biological name :Tes
  
Synonyms : Tes / testis derived transcript
  
Possible biological names infered from orthology : Q9UGI8 / testin LIM domain protein
  
Species: Mus musculus
  
Chr. number: 6
Strand: 1
Band: A2
Gene start: 17065149
Gene end: 17105828
  
Corresponding Affymetrix probe sets: 10536483 (MoGene1.0st)   1424246_a_at (Mouse Genome 430 2.0 Array)   1460378_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000118791
Ensembl peptide - ENSMUSP00000075950
Ensembl peptide - ENSMUSP00000111127
NCBI entrez gene - 21753     See in Manteia.
MGI - MGI:105081
RefSeq - NM_207176
RefSeq Peptide - NP_997059
swissprot - D6RH72
swissprot - Q3ULB1
swissprot - Q921W7
Ensembl - ENSMUSG00000029552
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tesENSDARG00000051857Danio rerio
 TESENSGALG00000031934Gallus gallus
 TESENSG00000135269Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Gm4907 / TES* / Q9UGI8* / testin LIM domain protein*ENSMUSG0000006811382
Gm4985 / TES* / Q9UGI8* / testin LIM domain protein*ENSMUSG0000009010277
Lmcd1 / Q8VEE1 / LIM and cysteine-rich domains 1 / Q9NZU5*ENSMUSG0000005760442
Q80VL3 / Prickle3 / Prickle planar cell polarity protein 3 / O43900*ENSMUSG0000003114536
Q80Y24 / Prickle2 / prickle planar cell polarity protein 2 / Q7Z3G6*ENSMUSG0000003002035
Q3U5C7 / Prickle1 / Prickle-like protein 1 / Q96MT3* / prickle planar cell polarity protein 1*ENSMUSG0000003615830
Gm21981 / Q2TBC4* / PRICKLE4* / AL365205.1* / prickle planar cell polarity protein 4*ENSMUSG0000007944420
Prickle4 / prickle planar cell polarity protein 4 / Q2TBC4* / AL365205.1*ENSMUSG0000009654920


Protein motifs (from Interpro)
Interpro ID Name
 IPR001781  Zinc finger, LIM-type
 IPR010442  PET domain
 IPR027683  Testin
 IPR033724  PET testin
 IPR034958  Testin, LIM domain 1
 IPR034959  Testin, LIM domain 2
 IPR034960  Testin, LIM domain 3


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0042127 regulation of cell proliferation IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002038 carcinoma "malignant neoplasm arising from epithelial cells, usually glandular or squamous" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:58877]
Show

Allelic Composition: Gdf11tm1Sjl/Gdf11tm1Sjl
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

Allelic Composition: Testm1Cro/Tes+
Genetic Background: involves: 129X1/SvJ * C57BL/6J

 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Cd74tm1Liz/Cd74tm1Liz,H2-DMatm1Luc/H2-DMatm1Luc,Tg(CD74)AR194Ayr/?
Genetic Background: involves: 129S/SvEv * 129S4/SvJae * C57BL/6J * DBA/2J

 MP:0010301 increased stomach tumor incidence "greater than the expected number of neoplasms in the gastric tissue usually in the form of a distinct mass, in a specific population in a given time period" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Gdf11tm1Sjl/Gdf11tm1Sjl
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

Allelic Composition: Testm1Cro/Tes+
Genetic Background: involves: 129X1/SvJ * C57BL/6J

 MP:0013575 abnormal forestomach-glandular stomach junction morphology "any structural anomaly of the distinct low fold of tissue that separates the non-glandular area of the stomach (forestomach) from the glandular stomach; the limiting ridge extends circumferentially from the large curvature of the stomach to the small curvature, just below the esophagus; at the esophagus, the course of the limiting ridge bends into a U-shape and almost surrounds the esophageal opening" [http://www.google.com/url?sa=t&rct=j&q=&esrc=s&source=web&cd=2&ved=0CCUQFjAB&url=http%3A%2F%2Fjournals.usamvcluj.ro%2Findex.php%2Fveterinary%2Farticle%2Fdownload%2F5889%2F5384&ei=nQ61VJvFEMuQyASZpYGgCw&usg=AFQjCNHtPvbkRJR7v3Jh2Ht2z-s9qVBLGA&bvm=bv.83339334,d.aWw&cad=rja, MGI:anna]
Show

Allelic Composition: Gdf11tm1Sjl/Gdf11tm1Sjl
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

Allelic Composition: Testm1Cro/Tes+
Genetic Background: involves: 129X1/SvJ * C57BL/6J

 MP:0013576 small forestomach "reduced size of the distinct rodent non-glandular region of the stomach which is demarcated from the glandular stomach by the limiting ridge (margo plicatus)" [MGI:Anna]
Show

Allelic Composition: Gdf11tm1Sjl/Gdf11tm1Sjl
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J

Allelic Composition: Testm1Cro/Tes+
Genetic Background: involves: 129X1/SvJ * C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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