ENSMUSG00000030243


Mus musculus

Features
Gene ID: ENSMUSG00000030243
  
Biological name :Recql
  
Synonyms : Q9Z129 / Recql / RecQ protein-like
  
Possible biological names infered from orthology : P46063 / RecQ like helicase
  
Species: Mus musculus
  
Chr. number: 6
Strand: -1
Band: G2
Gene start: 142350342
Gene end: 142387087
  
Corresponding Affymetrix probe sets: 10549057 (MoGene1.0st)   1418339_at (Mouse Genome 430 2.0 Array)   1425798_a_at (Mouse Genome 430 2.0 Array)   1436371_at (Mouse Genome 430 2.0 Array)   1439047_s_at (Mouse Genome 430 2.0 Array)   1447198_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000120951
Ensembl peptide - ENSMUSP00000122328
Ensembl peptide - ENSMUSP00000145179
Ensembl peptide - ENSMUSP00000122409
Ensembl peptide - ENSMUSP00000032370
Ensembl peptide - ENSMUSP00000098394
Ensembl peptide - ENSMUSP00000107434
Ensembl peptide - ENSMUSP00000119452
NCBI entrez gene - 19691     See in Manteia.
MGI - MGI:103021
RefSeq - NM_001355511
RefSeq - XM_017321469
RefSeq - XM_017321468
RefSeq - XM_011241573
RefSeq - NM_023042
RefSeq - NM_001204906
RefSeq - NM_001204907
RefSeq Peptide - NP_001191835
RefSeq Peptide - NP_001191836
RefSeq Peptide - NP_001342440
RefSeq Peptide - NP_075529
swissprot - F6S4D9
swissprot - D3Z6T0
swissprot - Q3UUK0
swissprot - Q9Z129
swissprot - D3YZW9
swissprot - E9Q3N0
swissprot - F7DB73
Ensembl - ENSMUSG00000030243
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 recqlENSDARG00000007175Danio rerio
 RECQLENSGALG00000013174Gallus gallus
 RECQLENSG00000004700Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Blm / O88700 / Bloom syndrome protein homolog / P54132* / Bloom syndrome RecQ like helicase*ENSMUSG0000003052834
Wrn / O09053 / Werner syndrome RecQ like helicase / Q14191*ENSMUSG0000003158326
Q8VID5 / Recql5 / ATP-dependent DNA helicase Q5 / O94762* / RecQ like helicase 5*ENSMUSG0000002075226
Recql4 / RecQ like helicase 4ENSMUSG0000003376221


Protein motifs (from Interpro)
Interpro ID Name
 IPR001650  Helicase, C-terminal
 IPR004589  DNA helicase, ATP-dependent, RecQ type
 IPR011545  DEAD/DEAH box helicase domain
 IPR014001  Helicase superfamily 1/2, ATP-binding domain
 IPR018982  RQC domain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR032284  ATP-dependent DNA helicase RecQ, zinc-binding domain
 IPR036388  Winged helix-like DNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000724 double-strand break repair via homologous recombination IBA
 biological_processGO:0000733 DNA strand renaturation IEA
 biological_processGO:0006260 DNA replication IEA
 biological_processGO:0006281 DNA repair IEA
 biological_processGO:0006310 DNA recombination IEA
 biological_processGO:0032508 DNA duplex unwinding IEA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005694 chromosome IBA
 cellular_componentGO:0005737 cytoplasm IBA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003677 DNA binding IBA
 molecular_functionGO:0003678 DNA helicase activity IEA
 molecular_functionGO:0004386 helicase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008026 ATP-dependent helicase activity IEA
 molecular_functionGO:0009378 four-way junction helicase activity IBA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0036310 annealing helicase activity IEA
 molecular_functionGO:0043140 ATP-dependent 3"-5" DNA helicase activity IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0003701 elevated level of sister chromatid exchange "increased number of crossovers between sister chromatids during meiosis resulting in increased numbers of reciprocal exchanges of DNA between the two chromosomes" [hdene:Howard Dene , Mouse Genome Informatics Curator, J:97667]
Show

Allelic Composition: Ptges3Gt(W069F07)Wrst/Ptges3Gt(W069F07)Wrst
Genetic Background: involves: 129X1/SvJ * C57BL/6

 MP:0003702 abnormal chromosome morphology "anomalies in the structure of the compact, intertwined molecules of DNA found in the nucleus which carry genetic information " [hdene:Howard Dene , Mouse Genome Informatics Curator]
Show

Allelic Composition: Ptges3Gt(W069F07)Wrst/Ptges3Gt(W069F07)Wrst
Genetic Background: involves: 129X1/SvJ * C57BL/6

 MP:0004024 aneuploidy "chromosome count is not an exact multiple of the haploid number " [llw2:Linda Washburn , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Ptges3Gt(W069F07)Wrst/Ptges3Gt(W069F07)Wrst
Genetic Background: involves: 129X1/SvJ * C57BL/6

 MP:0004029 spontaneous chromosome breakage "chromosome breakage due to inherent instability of chromosomes" [llw2:Linda Washburn , Mouse Genome Informatics Curator]
Show

Allelic Composition: Ptges3Gt(W069F07)Wrst/Ptges3Gt(W069F07)Wrst
Genetic Background: involves: 129X1/SvJ * C57BL/6

 MP:0011704 decreased fibroblast proliferation "reduction in the expansion rate of a fibroblast cell population by cell division" [MGI:csmith]
Show

Allelic Composition: Ptges3Gt(W069F07)Wrst/Ptges3Gt(W069F07)Wrst
Genetic Background: involves: 129X1/SvJ * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr