ENSMUSG00000030401


Mus musculus

Features
Gene ID: ENSMUSG00000030401
  
Biological name :Rtn2
  
Synonyms : O70622 / reticulon 2 (Z-band associated protein) / Rtn2
  
Possible biological names infered from orthology : O75298 / reticulon 2
  
Species: Mus musculus
  
Chr. number: 7
Strand: 1
Band: A3
Gene start: 19282624
Gene end: 19296160
  
Corresponding Affymetrix probe sets: 10550638 (MoGene1.0st)   1419056_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000032559
Ensembl peptide - ENSMUSP00000104108
NCBI entrez gene - 20167     See in Manteia.
MGI - MGI:107612
RefSeq - NM_013648
RefSeq - NM_001025364
RefSeq Peptide - NP_001020535
RefSeq Peptide - NP_038676
swissprot - O70622
swissprot - Q6IM74
swissprot - Q6IM75
Ensembl - ENSMUSG00000030401
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rtn2aENSDARG00000016088Danio rerio
 rtn2bENSDARG00000057027Danio rerio
 RTN2ENSG00000125744Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Rtn1 / Q8K0T0 / reticulon 1 / Q16799*ENSMUSG0000002108730
Rtn4 / Q99P72 / reticulon 4 / Q9NQC3*ENSMUSG0000002045830
Rtn3 / Q9ES97 / Reticulon-3 / O95197*ENSMUSG0000002475825


Protein motifs (from Interpro)
Interpro ID Name
 IPR003388  Reticulon


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0046324 regulation of glucose import IMP
 biological_processGO:0065002 intracellular protein transmembrane transport IMP
 cellular_componentGO:0005783 endoplasmic reticulum ISO
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0014802 terminal cisterna IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030315 T-tubule IDA
 molecular_functionGO:0003674 molecular_function ND


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000188 abnormal circulating glucose level "anomalous concentration in the blood of this major monosaccharide of the body; it is an important energy source" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Kdm3atm1.1Jsak/Kdm3atm1.1Jsak
Genetic Background: involves: C57BL/6 * CBA

 MP:0030022 decreased muscle cell glucose uptake "reduced ability of muscle cells to take in glucose" [MGI:anna]
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Allelic Composition: Kdm3atm1.1Jsak/Kdm3atm1.1Jsak
Genetic Background: involves: C57BL/6 * CBA

Allelic Composition: Rtn2tm1Lex/Rtn2tm1Lex
Genetic Background: involves: 129S/SvEvBrd

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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